methylprednisolone-3183 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the methylprednisolone-3183 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADAM22 ADAM metallopeptidase domain 22
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
APLP1 amyloid beta (A4) precursor-like protein 1
APP amyloid beta (A4) precursor protein
ARG1 arginase 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ASIP agouti signaling protein
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BDNF brain-derived neurotrophic factor
BTF3P11 basic transcription factor 3 pseudogene 11
C3ORF36 chromosome 3 open reading frame 36
CABP2 calcium binding protein 2
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCL2 chemokine (C-C motif) ligand 2
CD22 CD22 molecule
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPNE7 copine VII
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYSLTR1 cysteinyl leukotriene receptor 1
DFNB31 deafness, autosomal recessive 31
ESR1 estrogen receptor 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF22 fibroblast growth factor 22
FH fumarate hydratase
FKBP10 FK506 binding protein 10, 65 kDa
FSCN1 fascin actin-bundling protein 1
FSCN3 fascin actin-bundling protein 3, testicular
FSTL3 follistatin-like 3 (secreted glycoprotein)
GM2A GM2 ganglioside activator
GPR68 G protein-coupled receptor 68
GPSM3 G-protein signaling modulator 3
HAMP hepcidin antimicrobial peptide
HOXD9 homeobox D9
HPCAL4 hippocalcin like 4
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IHH indian hedgehog
IRF4 interferon regulatory factor 4
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLF6 Kruppel-like factor 6
KLF8 Kruppel-like factor 8
KLRD1 killer cell lectin-like receptor subfamily D, member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
MARK1 MAP/microtubule affinity-regulating kinase 1
MAU2 MAU2 sister chromatid cohesion factor
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
N4BP3 NEDD4 binding protein 3
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRP2 neuropilin 2
PBOV1 prostate and breast cancer overexpressed 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4C phosphodiesterase 4C, cAMP-specific
PEG3 paternally expressed 3
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PKNOX2 PBX/knotted 1 homeobox 2
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POFUT1 protein O-fucosyltransferase 1
PRAMEF10 PRAME family member 10
PRB1 proline-rich protein BstNI subfamily 1
PRX periaxin
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTPRM protein tyrosine phosphatase, receptor type, M
RAB6B RAB6B, member RAS oncogene family
RGS5 regulator of G-protein signaling 5
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFTPB surfactant protein B
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SPAG8 sperm associated antigen 8
SPRR1A small proline-rich protein 1A
SRSF7 serine/arginine-rich splicing factor 7
SV2B synaptic vesicle glycoprotein 2B
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAS2R10 taste receptor, type 2, member 10
TAT tyrosine aminotransferase
TIMELESS timeless circadian clock
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNS1 tensin 1
TSKS testis-specific serine kinase substrate
TTLL4 tubulin tyrosine ligase-like family member 4
ZNF235 zinc finger protein 235
ZNF81 zinc finger protein 81

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACBD4 acyl-CoA binding domain containing 4
ADCY6 adenylate cyclase 6
ADCY7 adenylate cyclase 7
ADM adrenomedullin
AFAP1 actin filament associated protein 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANP32A-IT1 ANP32A intronic transcript 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ART1 ADP-ribosyltransferase 1
ATAD5 ATPase family, AAA domain containing 5
ATP13A2 ATPase type 13A2
ATP7B ATPase, Cu++ transporting, beta polypeptide
BBC3 BCL2 binding component 3
C2ORF27A chromosome 2 open reading frame 27A
C7ORF43 chromosome 7 open reading frame 43
CCDC132 coiled-coil domain containing 132
CCDC69 coiled-coil domain containing 69
CD53 CD53 molecule
CHKB choline kinase beta
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRYBG3 beta-gamma crystallin domain containing 3
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DOC2A double C2-like domains, alpha
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EXOC6B exocyst complex component 6B
FAM169A family with sequence similarity 169, member A
FLJ11710 uncharacterized protein FLJ11710
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPRC5C G protein-coupled receptor, class C, group 5, member C
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H2AL histone cluster 1, H2al
HIST1H2BC histone cluster 1, H2bc
ITGA10 integrin, alpha 10
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM8 lysine (K)-specific demethylase 8
KIAA1456 KIAA1456
KIF13A kinesin family member 13A
KIF13B kinesin family member 13B
KRT83 keratin 83, type II
LDHB lactate dehydrogenase B
LHX1 LIM homeobox 1
LHX6 LIM homeobox 6
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC729164 hCG1732469
LYZ lysozyme
MAN2C1 mannosidase, alpha, class 2C, member 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCOLN1 mucolipin 1
MED9 mediator complex subunit 9
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPO myeloperoxidase
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NLRX1 NLR family member X1
NPIPB3 nuclear pore complex interacting protein family, member B3
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLXNA3 plexin A3
PNPLA6 patatin-like phospholipase domain containing 6
PODXL2 podocalyxin-like 2
PQLC1 PQ loop repeat containing 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF31 ring finger protein 31
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMAD5 SMAD family member 5
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRGN serglycin
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
STX1A syntaxin 1A (brain)
TNRC6B trinucleotide repeat containing 6B
TTC33 tetratricopeptide repeat domain 33
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WNT10B wingless-type MMTV integration site family, member 10B
WWC2 WW and C2 domain containing 2
ZBTB44 zinc finger and BTB domain containing 44
ZC3H12A zinc finger CCCH-type containing 12A
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZMAT5 zinc finger, matrin-type 5
ZNF227 zinc finger protein 227
ZNF324 zinc finger protein 324
ZNF510 zinc finger protein 510
ZNF573 zinc finger protein 573