methylprednisolone-7137 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the methylprednisolone-7137 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
AKAP12 A kinase (PRKA) anchor protein 12
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
APLP2 amyloid beta (A4) precursor-like protein 2
APOM apolipoprotein M
ATP11A ATPase, class VI, type 11A
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AXIN1 axin 1
BBS9 Bardet-Biedl syndrome 9
C14ORF1 chromosome 14 open reading frame 1
C16ORF59 chromosome 16 open reading frame 59
C16ORF62 chromosome 16 open reading frame 62
C1ORF115 chromosome 1 open reading frame 115
C1RL complement component 1, r subcomponent-like
C9ORF156 chromosome 9 open reading frame 156
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD40 CD40 molecule, TNF receptor superfamily member 5
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPJ centromere protein J
CIDEB cell death-inducing DFFA-like effector b
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CREB3L1 cAMP responsive element binding protein 3-like 1
CRY2 cryptochrome circadian clock 2
CXCL3 chemokine (C-X-C motif) ligand 3
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DUSP1 dual specificity phosphatase 1
EFNA3 ephrin-A3
EFNB2 ephrin-B2
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV1 ets variant 1
FAM105A family with sequence similarity 105, member A
FBXL15 F-box and leucine-rich repeat protein 15
FCF1 FCF1 rRNA-processing protein
FGFR2 fibroblast growth factor receptor 2
FKBP5 FK506 binding protein 5
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLUL glutamate-ammonia ligase
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
HLX H2.0-like homeobox
HNF1B HNF1 homeobox B
IFI6 interferon, alpha-inducible protein 6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL11 interleukin 11
IRS2 insulin receptor substrate 2
KIF5C kinesin family member 5C
KRT34 keratin 34, type I
LAMC2 laminin, gamma 2
MAST4 microtubule associated serine/threonine kinase family member 4
MED6 mediator complex subunit 6
MFSD6 major facilitator superfamily domain containing 6
MN1 meningioma (disrupted in balanced translocation) 1
MT1X metallothionein 1X
MUC1 mucin 1, cell surface associated
MUC3B mucin 3B, cell surface associated
NAIP NLR family, apoptosis inhibitory protein
NAV2 neuron navigator 2
NDE1 nudE neurodevelopment protein 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NNMT nicotinamide N-methyltransferase
NOP16 NOP16 nucleolar protein
NPFFR1 neuropeptide FF receptor 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
PARVA parvin, alpha
PDE12 phosphodiesterase 12
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PER1 period circadian clock 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLAT plasminogen activator, tissue
PLEKHO1 pleckstrin homology domain containing, family O member 1
PTBP3 polypyrimidine tract binding protein 3
RAB31 RAB31, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RANBP3 RAN binding protein 3
RAP1GAP2 RAP1 GTPase activating protein 2
RUNX3 runt-related transcription factor 3
SAMD4A sterile alpha motif domain containing 4A
SEC24D SEC24 family member D
SETDB1 SET domain, bifurcated 1
SF3B3 splicing factor 3b, subunit 3, 130kDa
SGSM2 small G protein signaling modulator 2
SIRT3 sirtuin 3
SMG7 SMG7 nonsense mediated mRNA decay factor
SNRPN small nuclear ribonucleoprotein polypeptide N
SRD5A3 steroid 5 alpha-reductase 3
SREBF1 sterol regulatory element binding transcription factor 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TNIK TRAF2 and NCK interacting kinase
TRIM25 tripartite motif containing 25
TSPAN1 tetraspanin 1
UBQLN4 ubiquilin 4
WT1 Wilms tumor 1
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABHD4 abhydrolase domain containing 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ANAPC2 anaphase promoting complex subunit 2
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATG2B autophagy related 2B
BAK1 BCL2-antagonist/killer 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
C17ORF85 chromosome 17 open reading frame 85
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNE1 cyclin E1
CCRL2 chemokine (C-C motif) receptor-like 2
CENPC centromere protein C
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLCF1 cardiotrophin-like cytokine factor 1
CLEC16A C-type lectin domain family 16, member A
CLEC2B C-type lectin domain family 2, member B
CLSPN claspin
CNTNAP1 contactin associated protein 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DMXL1 Dmx-like 1
DNA2 DNA replication helicase/nuclease 2
DSC2 desmocollin 2
EAF2 ELL associated factor 2
EFNA4 ephrin-A4
EGLN2 egl-9 family hypoxia-inducible factor 2
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
FPGS folylpolyglutamate synthase
GBX2 gastrulation brain homeobox 2
GDAP2 ganglioside induced differentiation associated protein 2
GLCE glucuronic acid epimerase
GPBP1L1 GC-rich promoter binding protein 1-like 1
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HMOX1 heme oxygenase 1
IFI35 interferon-induced protein 35
IL1B interleukin 1, beta
IL7R interleukin 7 receptor
IRF2 interferon regulatory factor 2
IRS1 insulin receptor substrate 1
KCTD15 potassium channel tetramerization domain containing 15
LPAR6 lysophosphatidic acid receptor 6
LRRC20 leucine rich repeat containing 20
MANSC1 MANSC domain containing 1
MAPK3 mitogen-activated protein kinase 3
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAST3 microtubule associated serine/threonine kinase 3
MBIP MAP3K12 binding inhibitory protein 1
MCMBP minichromosome maintenance complex binding protein
MSL1 male-specific lethal 1 homolog (Drosophila)
MTCL1 microtubule crosslinking factor 1
NINJ1 ninjurin 1
NLK nemo-like kinase
NPY1R neuropeptide Y receptor Y1
NXPE3 neurexophilin and PC-esterase domain family, member 3
PALMD palmdelphin
PILRB paired immunoglobin-like type 2 receptor beta
PLAU plasminogen activator, urokinase
PLD2 phospholipase D2
PLK2 polo-like kinase 2
POLH polymerase (DNA directed), eta
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PPL periplakin
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SDC3 syndecan 3
SETD1B SET domain containing 1B
SH2D4A SH2 domain containing 4A
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNX15 sorting nexin 15
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STK16 serine/threonine kinase 16
SUN2 Sad1 and UNC84 domain containing 2
THAP10 THAP domain containing 10
TM7SF2 transmembrane 7 superfamily member 2
TM7SF3 transmembrane 7 superfamily member 3
TMEM104 transmembrane protein 104
TMEM242 transmembrane protein 242
TMEM254 transmembrane protein 254
TRAPPC6A trafficking protein particle complex 6A
TTC26 tetratricopeptide repeat domain 26
TUBGCP5 tubulin, gamma complex associated protein 5
UNKL unkempt family zinc finger-like
VASP vasodilator-stimulated phosphoprotein
ZDHHC14 zinc finger, DHHC-type containing 14
ZDHHC18 zinc finger, DHHC-type containing 18
ZFP69B ZFP69 zinc finger protein B
ZMYM3 zinc finger, MYM-type 3
ZNF165 zinc finger protein 165
ZNF552 zinc finger protein 552