meticrane-1792 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the meticrane-1792 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ADGRG2 adhesion G protein-coupled receptor G2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APH1A APH1A gamma secretase subunit
ARHGAP10 Rho GTPase activating protein 10
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATP10D ATPase, class V, type 10D
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BBS9 Bardet-Biedl syndrome 9
BCL2L11 BCL2-like 11 (apoptosis facilitator)
CCDC186 coiled-coil domain containing 186
CCDC85C coiled-coil domain containing 85C
CCPG1 cell cycle progression 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CDV3 CDV3 homolog (mouse)
COBL cordon-bleu WH2 repeat protein
COL1A1 collagen, type I, alpha 1
CTSZ cathepsin Z
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
CYTH3 cytohesin 3
DEAF1 DEAF1 transcription factor
DHODH dihydroorotate dehydrogenase (quinone)
DPH5 diphthamide biosynthesis 5
EEF2 eukaryotic translation elongation factor 2
EPS8L1 EPS8-like 1
ERH enhancer of rudimentary homolog (Drosophila)
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR1 estrogen receptor 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM49B family with sequence similarity 49, member B
GALK2 galactokinase 2
GFRA1 GDNF family receptor alpha 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMGB1 high mobility group box 1
HMOX2 heme oxygenase 2
HNRNPK heterogeneous nuclear ribonucleoprotein K
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
KLK10 kallikrein-related peptidase 10
LOC81691 exonuclease NEF-sp
LRP2 low density lipoprotein receptor-related protein 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAPK7 mitogen-activated protein kinase 7
MATR3 matrin 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECR mitochondrial trans-2-enoyl-CoA reductase
MID2 midline 2
MSL3 male-specific lethal 3 homolog (Drosophila)
MUC1 mucin 1, cell surface associated
NAAA N-acylethanolamine acid amidase
NCKAP1 NCK-associated protein 1
NDE1 nudE neurodevelopment protein 1
NF1 neurofibromin 1
NGF nerve growth factor (beta polypeptide)
NKTR natural killer cell triggering receptor
NPFFR1 neuropeptide FF receptor 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PAX9 paired box 9
PEX1 peroxisomal biogenesis factor 1
PEX26 peroxisomal biogenesis factor 26
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POLQ polymerase (DNA directed), theta
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRB1 proline-rich protein BstNI subfamily 1
PRF1 perforin 1 (pore forming protein)
RAB27B RAB27B, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RBKS ribokinase
RECQL5 RecQ protein-like 5
RFX7 regulatory factor X, 7
RNF121 ring finger protein 121
RNF126P1 ring finger protein 126 pseudogene 1
RPS9 ribosomal protein S9
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SFTPB surfactant protein B
SHROOM2 shroom family member 2
SMC1A structural maintenance of chromosomes 1A
SMG5 SMG5 nonsense mediated mRNA decay factor
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRRM2 serine/arginine repetitive matrix 2
STK11 serine/threonine kinase 11
STK17B serine/threonine kinase 17b
STXBP6 syntaxin binding protein 6 (amisyn)
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCAF1 TRPM8 channel-associated factor 1
TEX261 testis expressed 261
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFF2 trefoil factor 2
TMEM63A transmembrane protein 63A
TXNRD3 thioredoxin reductase 3
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UTRN utrophin
WDR76 WD repeat domain 76
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF117 zinc finger protein 117
ZNF254 zinc finger protein 254
ZNF614 zinc finger protein 614

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ASB8 ankyrin repeat and SOCS box containing 8
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCAS3 breast carcinoma amplified sequence 3
BIN3 bridging integrator 3
BOLA1 bolA family member 1
C11ORF80 chromosome 11 open reading frame 80
CHPF chondroitin polymerizing factor
CHST10 carbohydrate sulfotransferase 10
CNPY3 canopy FGF signaling regulator 3
COG7 component of oligomeric golgi complex 7
CRIP2 cysteine-rich protein 2
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEPDC1 DEP domain containing 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIXDC1 DIX domain containing 1
DMBT1 deleted in malignant brain tumors 1
DMXL1 Dmx-like 1
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EFNA4 ephrin-A4
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EXOC5 exocyst complex component 5
FAIM Fas apoptotic inhibitory molecule
FBXW12 F-box and WD repeat domain containing 12
FDXR ferredoxin reductase
FKBP2 FK506 binding protein 2, 13kDa
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GLTP glycolipid transfer protein
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPHN gephyrin
HLA-J major histocompatibility complex, class I, J (pseudogene)
IL7R interleukin 7 receptor
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KLC2 kinesin light chain 2
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL26 kelch-like family member 26
LGMN legumain
LHX6 LIM homeobox 6
LTBP3 latent transforming growth factor beta binding protein 3
LYRM2 LYR motif containing 2
MAL mal, T-cell differentiation protein
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
METTL2B methyltransferase like 2B
METTL8 methyltransferase like 8
MTERF1 mitochondrial transcription termination factor 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NABP2 nucleic acid binding protein 2
NARFL nuclear prelamin A recognition factor-like
NIP7 NIP7, nucleolar pre-rRNA processing protein
NT5E 5'-nucleotidase, ecto (CD73)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIBF1 progesterone immunomodulatory binding factor 1
PILRB paired immunoglobin-like type 2 receptor beta
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POR P450 (cytochrome) oxidoreductase
PPL periplakin
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PRSS2 protease, serine, 2 (trypsin 2)
PTK6 protein tyrosine kinase 6
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RAP1GAP2 RAP1 GTPase activating protein 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNF25 ring finger protein 25
RPS21 ribosomal protein S21
S100A4 S100 calcium binding protein A4
SIPA1 signal-induced proliferation-associated 1
SNX10 sorting nexin 10
SNX16 sorting nexin 16
SOAT1 sterol O-acyltransferase 1
SPAG4 sperm associated antigen 4
SPAG7 sperm associated antigen 7
SPATA2L spermatogenesis associated 2-like
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
THOP1 thimet oligopeptidase 1
TICAM1 toll-like receptor adaptor molecule 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM156 transmembrane protein 156
TMEM184C transmembrane protein 184C
TMEM2 transmembrane protein 2
TMUB2 transmembrane and ubiquitin-like domain containing 2
TOM1L1 target of myb1 (chicken)-like 1
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSNAX translin-associated factor X
TTPAL tocopherol (alpha) transfer protein-like
TUBA3D tubulin, alpha 3d
UFSP2 UFM1-specific peptidase 2
USP32 ubiquitin specific peptidase 32
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZDHHC18 zinc finger, DHHC-type containing 18
ZMAT5 zinc finger, matrin-type 5
ZNF134 zinc finger protein 134
ZNF282 zinc finger protein 282
ZNF787 zinc finger protein 787