meticrane-1834 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the meticrane-1834 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN4 actinin, alpha 4
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOL6 apolipoprotein L, 6
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BTF3 basic transcription factor 3
C16ORF59 chromosome 16 open reading frame 59
CCL23 chemokine (C-C motif) ligand 23
CEP41 centrosomal protein 41kDa
CLIC4 chloride intracellular channel 4
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CNTLN centlein, centrosomal protein
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSTA cystatin A (stefin A)
CXCR3 chemokine (C-X-C motif) receptor 3
CYBA cytochrome b-245, alpha polypeptide
DAPK1 death-associated protein kinase 1
DEK DEK proto-oncogene
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
ENO1 enolase 1, (alpha)
ERH enhancer of rudimentary homolog (Drosophila)
FDPS farnesyl diphosphate synthase
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GEMIN4 gem (nuclear organelle) associated protein 4
GK3P glycerol kinase 3 pseudogene
H2AFX H2A histone family, member X
HABP4 hyaluronan binding protein 4
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HMGN1 high mobility group nucleosome binding domain 1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
ICA1 islet cell autoantigen 1, 69kDa
ICAM2 intercellular adhesion molecule 2
IL11 interleukin 11
INA internexin neuronal intermediate filament protein, alpha
KDM5C lysine (K)-specific demethylase 5C
KRIT1 KRIT1, ankyrin repeat containing
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LBR lamin B receptor
LRRC41 leucine rich repeat containing 41
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP4 microtubule-associated protein 4
MARK4 MAP/microtubule affinity-regulating kinase 4
MKL1 megakaryoblastic leukemia (translocation) 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLPH melanophilin
MT1E metallothionein 1E
MZT2B mitotic spindle organizing protein 2B
NCOA2 nuclear receptor coactivator 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR0B2 nuclear receptor subfamily 0, group B, member 2
NUCLEOLIN nucleolin multifunctional protein
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PLD2 phospholipase D2
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PSPH phosphoserine phosphatase
RAB1A RAB1A, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RARS arginyl-tRNA synthetase
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REC8 REC8 meiotic recombination protein
RPL38 ribosomal protein L38
RPS16 ribosomal protein S16
RPS2 ribosomal protein S2
RYR2 ryanodine receptor 2 (cardiac)
SCCPDH saccharopine dehydrogenase (putative)
SEC24D SEC24 family member D
SERBP1 SERPINE1 mRNA binding protein 1
SH2D2A SH2 domain containing 2A
SH2D4A SH2 domain containing 4A
SIL1 SIL1 nucleotide exchange factor
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNW1 SNW domain containing 1
SPDEF SAM pointed domain containing ETS transcription factor
SPN sialophorin
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SUB1 SUB1 homolog (S. cerevisiae)
SUGP1 SURP and G patch domain containing 1
TBC1D2 TBC1 domain family, member 2
TCP11L1 t-complex 11, testis-specific-like 1
TEX261 testis expressed 261
TM7SF2 transmembrane 7 superfamily member 2
TMA7 translation machinery associated 7 homolog (S. cerevisiae)
TRAIP TRAF interacting protein
TRIP11 thyroid hormone receptor interactor 11
TSPYL2 TSPY-like 2
UBC ubiquitin C
UBOX5 U-box domain containing 5
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
ZBTB3 zinc finger and BTB domain containing 3
ZNF668 zinc finger protein 668
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARMC7 armadillo repeat containing 7
ARRB2 arrestin, beta 2
BAX BCL2-associated X protein
C11ORF95 chromosome 11 open reading frame 95
C2CD2 C2 calcium-dependent domain containing 2
CAPN15 calpain 15
CCDC15 coiled-coil domain containing 15
CCL20 chemokine (C-C motif) ligand 20
CENPB centromere protein B, 80kDa
CENPT centromere protein T
CHST10 carbohydrate sulfotransferase 10
CIDEB cell death-inducing DFFA-like effector b
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DEXI Dexi homolog (mouse)
DHDDS dehydrodolichyl diphosphate synthase
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
DTWD1 DTW domain containing 1
ETFB electron-transfer-flavoprotein, beta polypeptide
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GPALPP1 GPALPP motifs containing 1
GPATCH3 G patch domain containing 3
HDAC3 histone deacetylase 3
HSPA4L heat shock 70kDa protein 4-like
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IMPAD1 inositol monophosphatase domain containing 1
ISG15 ISG15 ubiquitin-like modifier
KIAA0556 KIAA0556
KIF13B kinesin family member 13B
KIFC1 kinesin family member C1
KLHL26 kelch-like family member 26
KRBOX4 KRAB box domain containing 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LZTR1 leucine-zipper-like transcription regulator 1
MCOLN1 mucolipin 1
MPDU1 mannose-P-dolichol utilization defect 1
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MXD3 MAX dimerization protein 3
NECAP2 NECAP endocytosis associated 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NPM3 nucleophosmin/nucleoplasmin 3
OCEL1 occludin/ELL domain containing 1
ODF2 outer dense fiber of sperm tails 2
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PFDN1 prefoldin subunit 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLAG1 pleiomorphic adenoma gene 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PNMA1 paraneoplastic Ma antigen 1
POR P450 (cytochrome) oxidoreductase
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAB33B RAB33B, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF141 ring finger protein 141
RPGR retinitis pigmentosa GTPase regulator
RPL39L ribosomal protein L39-like
SAMD9 sterile alpha motif domain containing 9
SETD6 SET domain containing 6
SETMAR SET domain and mariner transposase fusion gene
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMA4 glucuronidase, beta pseudogene
SMAD7 SMAD family member 7
SNX15 sorting nexin 15
SPI1 Spi-1 proto-oncogene
STX5 syntaxin 5
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
THOC6 THO complex 6
TMEM260 transmembrane protein 260
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOR4A torsin family 4, member A
TRIM22 tripartite motif containing 22
TRIM25 tripartite motif containing 25
TRIM26 tripartite motif containing 26
TRIM68 tripartite motif containing 68
TSPAN32 tetraspanin 32
TST thiosulfate sulfurtransferase (rhodanese)
TXNL4B thioredoxin-like 4B
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN4 ubiquilin 4
UPB1 ureidopropionase, beta
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP20 ubiquitin specific peptidase 20
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XAF1 XIAP associated factor 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF134 zinc finger protein 134
ZNF282 zinc finger protein 282
ZNF536 zinc finger protein 536
ZNF629 zinc finger protein 629
ZNF675 zinc finger protein 675
ZNF862 zinc finger protein 862