meticrane-5984 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the meticrane-5984 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
AK1 adenylate kinase 1
APP amyloid beta (A4) precursor protein
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BAHCC1 BAH domain and coiled-coil containing 1
C2ORF27A chromosome 2 open reading frame 27A
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEP72 centrosomal protein 72kDa
CGA glycoprotein hormones, alpha polypeptide
CNN1 calponin 1, basic, smooth muscle
COL4A1 collagen, type IV, alpha 1
CPNE7 copine VII
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSHL1 chorionic somatomammotropin hormone-like 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYTH1 cytohesin 1
DAGLA diacylglycerol lipase, alpha
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOC2B double C2-like domains, beta
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EMID1 EMI domain containing 1
FAM186A family with sequence similarity 186, member A
FAXDC2 fatty acid hydroxylase domain containing 2
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GAP43 growth associated protein 43
GIPR gastric inhibitory polypeptide receptor
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPATCH4 G patch domain containing 4
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRAMD1C GRAM domain containing 1C
GRIA3 glutamate receptor, ionotropic, AMPA 3
GYG2 glycogenin 2
GYPB glycophorin B (MNS blood group)
HIST1H3E histone cluster 1, H3e
IL36RN interleukin 36 receptor antagonist
IL4R interleukin 4 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM4C lysine (K)-specific demethylase 4C
LAMA4 laminin, alpha 4
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMO7 LIM domain 7
LOC644450 uncharacterized LOC644450
LZTS1 leucine zipper, putative tumor suppressor 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MNMIP1 manchette microtubule inner protein 1
MRPS18C mitochondrial ribosomal protein S18C
MSX2 msh homeobox 2
MTA1 metastasis associated 1
MUC6 mucin 6, oligomeric mucus/gel-forming
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NEU3 sialidase 3 (membrane sialidase)
NKX2-1 NK2 homeobox 1
NOL10 nucleolar protein 10
NOL4 nucleolar protein 4
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
OTOR otoraplin
PCDHB8 protocadherin beta 8
PDGFB platelet-derived growth factor beta polypeptide
PHF1 PHD finger protein 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLVAP plasmalemma vesicle associated protein
PLXNB1 plexin B1
PLXNB3 plexin B3
PRDM14 PR domain containing 14
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGS12 regulator of G-protein signaling 12
RUNX1 runt-related transcription factor 1
SH3BP2 SH3-domain binding protein 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35E2 solute carrier family 35, member E2
SLC39A9 solute carrier family 39, member 9
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SSX1 synovial sarcoma, X breakpoint 1
STAB2 stabilin 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STXBP5L syntaxin binding protein 5-like
SUGP1 SURP and G patch domain containing 1
SVIL supervillin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THRB thyroid hormone receptor, beta
TMOD1 tropomodulin 1
TRIM49 tripartite motif containing 49
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TSC22D2 TSC22 domain family, member 2
TTLL7 tubulin tyrosine ligase-like family member 7
UBOX5 U-box domain containing 5
USB1 U6 snRNA biogenesis 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WIPF2 WAS/WASL interacting protein family, member 2
WNT1 wingless-type MMTV integration site family, member 1
ZIC4 Zic family member 4
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACSF2 acyl-CoA synthetase family member 2
AHR aryl hydrocarbon receptor
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP7B ATPase, Cu++ transporting, beta polypeptide
BAG4 BCL2-associated athanogene 4
BBC3 BCL2 binding component 3
BIK BCL2-interacting killer (apoptosis-inducing)
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF30 chromosome 11 open reading frame 30
C22ORF29 chromosome 22 open reading frame 29
CA11 carbonic anhydrase XI
CCDC186 coiled-coil domain containing 186
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDADC1 cytidine and dCMP deaminase domain containing 1
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEB cell death-inducing DFFA-like effector b
CNGB3 cyclic nucleotide gated channel beta 3
CRYZL1 crystallin, zeta (quinone reductase)-like 1
DCAF16 DDB1 and CUL4 associated factor 16
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM63A family with sequence similarity 63, member A
FBRS fibrosin
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GCC2 GRIP and coiled-coil domain containing 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
IFI6 interferon, alpha-inducible protein 6
IFT140 intraflagellar transport 140
IFT22 intraflagellar transport 22
ITPKB inositol-trisphosphate 3-kinase B
KIAA0894 KIAA0894 protein
KRBOX4 KRAB box domain containing 4
LIN7B lin-7 homolog B (C. elegans)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC257152 uncharacterized LOC257152
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MOCS3 molybdenum cofactor synthesis 3
MPI mannose phosphate isomerase
MVP major vault protein
NDE1 nudE neurodevelopment protein 1
NUPL2 nucleoporin like 2
ONECUT2 one cut homeobox 2
ORC1 origin recognition complex, subunit 1
PDAP1 PDGFA associated protein 1
PROS1 protein S (alpha)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RAB3D RAB3D, member RAS oncogene family
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SCD5 stearoyl-CoA desaturase 5
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRYD7 SPRY domain containing 7
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3 stromal antigen 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TDRD1 tudor domain containing 1
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TMC5 transmembrane channel-like 5
TMEM180 transmembrane protein 180
TMOD3 tropomodulin 3 (ubiquitous)
TRIM16 tripartite motif containing 16
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TTBK2 tau tubulin kinase 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF136 zinc finger protein 136
ZNF160 zinc finger protein 160
ZNF329 zinc finger protein 329
ZNF430 zinc finger protein 430
ZNF480 zinc finger protein 480
ZNF492 zinc finger protein 492
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF778 zinc finger protein 778