| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the metitepine-3231 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADCK4 | aarF domain containing kinase 4 |
| ADGRB3 | adhesion G protein-coupled receptor B3 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGRN | agrin |
| ANXA2P1 | annexin A2 pseudogene 1 |
| APOC1 | apolipoprotein C-I |
| AQP1 | aquaporin 1 (Colton blood group) |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ATF3 | activating transcription factor 3 |
| ATN1 | atrophin 1 |
| ATP10B | ATPase, class V, type 10B |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCPG1 | cell cycle progression 1 |
| CD22 | CD22 molecule |
| CD8A | CD8a molecule |
| CDHR2 | cadherin-related family member 2 |
| CDK13 | cyclin-dependent kinase 13 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CLTA | clathrin, light chain A |
| COL3A1 | collagen, type III, alpha 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DOK3 | docking protein 3 |
| DUOX1 | dual oxidase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| FAM182B | family with sequence similarity 182, member B |
| GHRHR | growth hormone releasing hormone receptor |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| IBSP | integrin-binding sialoprotein |
| ICOS | inducible T-cell co-stimulator |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INSIG1 | insulin induced gene 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPIN1 | lipin 1 |
| LTB4R | leukotriene B4 receptor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK7 | mitogen-activated protein kinase 7 |
| METTL7A | methyltransferase like 7A |
| MR1 | major histocompatibility complex, class I-related |
| MST1 | macrophage stimulating 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDRG2 | NDRG family member 2 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NEB | nebulin |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME5 | NME/NM23 family member 5 |
| NPTX1 | neuronal pentraxin I |
| NRG2 | neuregulin 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NYNRIN | NYN domain and retroviral integrase containing |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PER1 | period circadian clock 1 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLA2G3 | phospholipase A2, group III |
| PLAU | plasminogen activator, urokinase |
| POU3F1 | POU class 3 homeobox 1 |
| POU3F4 | POU class 3 homeobox 4 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RND1 | Rho family GTPase 1 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERHL2 | serine hydrolase-like 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIRT4 | sirtuin 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SLIT1 | slit homolog 1 (Drosophila) |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SRCAP | Snf2-related CREBBP activator protein |
| STATH | statherin |
| STK17A | serine/threonine kinase 17a |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TPP1 | tripeptidyl peptidase I |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSC22D4 | TSC22 domain family, member 4 |
| TTC38 | tetratricopeptide repeat domain 38 |
| YIPF2 | Yip1 domain family, member 2 |
| ZNF345 | zinc finger protein 345 |
| ZNF358 | zinc finger protein 358 |
| ZNF646 | zinc finger protein 646 |
| ZSCAN12 | zinc finger and SCAN domain containing 12 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| AQP7 | aquaporin 7 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BMP4 | bone morphogenetic protein 4 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C5AR2 | complement component 5a receptor 2 |
| CBX8 | chromobox homolog 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDK20 | cyclin-dependent kinase 20 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CENPO | centromere protein O |
| CES1 | carboxylesterase 1 |
| CFAP45 | cilia and flagella associated protein 45 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DPYS | dihydropyrimidinase |
| DUSP2 | dual specificity phosphatase 2 |
| FADS2 | fatty acid desaturase 2 |
| FAM131A | family with sequence similarity 131, member A |
| FKBP5 | FK506 binding protein 5 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GAMT | guanidinoacetate N-methyltransferase |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4F | histone cluster 1, H4f |
| HOXC5 | homeobox C5 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIAA0319L | KIAA0319-like |
| LDHB | lactate dehydrogenase B |
| LHX6 | LIM homeobox 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINS | lines homolog (Drosophila) |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LYZ | lysozyme |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCC | mutated in colorectal cancers |
| MID2 | midline 2 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTSS1L | metastasis suppressor 1-like |
| MYO1E | myosin IE |
| NLGN1 | neuroligin 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OR7A10 | olfactory receptor, family 7, subfamily A, member 10 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PGR | progesterone receptor |
| PODNL1 | podocan-like 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRSS16 | protease, serine, 16 (thymus) |
| RAB3A | RAB3A, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RCAN3 | RCAN family member 3 |
| RELN | reelin |
| RIN1 | Ras and Rab interactor 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| ROM1 | retinal outer segment membrane protein 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| STAB2 | stabilin 2 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| TMEM180 | transmembrane protein 180 |
| TRAIP | TRAF interacting protein |
| TRIM25 | tripartite motif containing 25 |
| TSPYL2 | TSPY-like 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WDR62 | WD repeat domain 62 |
| ZIC3 | Zic family member 3 |
| ZNF134 | zinc finger protein 134 |
| ZNF34 | zinc finger protein 34 |
| ZNF350 | zinc finger protein 350 |
| ZNF696 | zinc finger protein 696 |
| ZNF778 | zinc finger protein 778 |
| ZNF862 | zinc finger protein 862 |
| ZW10 | zw10 kinetochore protein |
