| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the metitepine-5413 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| APOC1 | apolipoprotein C-I |
| ARTN | artemin |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATF3 | activating transcription factor 3 |
| ATF6B | activating transcription factor 6 beta |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BMP5 | bone morphogenetic protein 5 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CCDC28B | coiled-coil domain containing 28B |
| CCNG2 | cyclin G2 |
| CD47 | CD47 molecule |
| CDC14B | cell division cycle 14B |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DRD5 | dopamine receptor D5 |
| DTNA | dystrobrevin, alpha |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| ETV1 | ets variant 1 |
| FAM188A | family with sequence similarity 188, member A |
| FFAR2 | free fatty acid receptor 2 |
| FHIT | fragile histidine triad |
| FHL5 | four and a half LIM domains 5 |
| FLOT1 | flotillin 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GHRHR | growth hormone releasing hormone receptor |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GM2A | GM2 ganglioside activator |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H4D | histone cluster 1, H4d |
| HOXA2 | homeobox A2 |
| HOXB6 | homeobox B6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 |
| JUN | jun proto-oncogene |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KIF3C | kinesin family member 3C |
| KLHL24 | kelch-like family member 24 |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MST1L | macrophage stimulating 1-like |
| MTCP1 | mature T-cell proliferation 1 |
| MUC3B | mucin 3B, cell surface associated |
| MVD | mevalonate (diphospho) decarboxylase |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| N4BP3 | NEDD4 binding protein 3 |
| NAV2 | neuron navigator 2 |
| NEK9 | NIMA-related kinase 9 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLAU | plasminogen activator, urokinase |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLM | polymerase (DNA directed), mu |
| PRDX2 | peroxiredoxin 2 |
| RAB5B | RAB5B, member RAS oncogene family |
| RARB | retinoic acid receptor, beta |
| RNMT | RNA (guanine-7-) methyltransferase |
| SELL | selectin L |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SRP72 | signal recognition particle 72kDa |
| TEX14 | testis expressed 14 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TLR2 | toll-like receptor 2 |
| TREX1 | three prime repair exonuclease 1 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| ZNF419 | zinc finger protein 419 |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACTL8 | actin-like 8 |
| AEBP1 | AE binding protein 1 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| BST2 | bone marrow stromal cell antigen 2 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C5 | complement component 5 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC85C | coiled-coil domain containing 85C |
| CD8A | CD8a molecule |
| CES3 | carboxylesterase 3 |
| CFAP44 | cilia and flagella associated protein 44 |
| CFD | complement factor D (adipsin) |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CUEDC1 | CUE domain containing 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DOCK1 | dedicator of cytokinesis 1 |
| DOCK4 | dedicator of cytokinesis 4 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ESRP2 | epithelial splicing regulatory protein 2 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM204A | family with sequence similarity 204, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H3G | histone cluster 1, H3g |
| IFI27 | interferon, alpha-inducible protein 27 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KAT2A | K(lysine) acetyltransferase 2A |
| KRT13 | keratin 13, type I |
| KRT15 | keratin 15, type I |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| MAMLD1 | mastermind-like domain containing 1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MYO1F | myosin IF |
| MYOZ3 | myozenin 3 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NME5 | NME/NM23 family member 5 |
| NOL10 | nucleolar protein 10 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OLFML2A | olfactomedin-like 2A |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RECQL4 | RecQ protein-like 4 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF39 | ring finger protein 39 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST5 | suppression of tumorigenicity 5 |
| TAOK1 | TAO kinase 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TLR5 | toll-like receptor 5 |
| TMEM120B | transmembrane protein 120B |
| TMEM159 | transmembrane protein 159 |
| TMEM212 | transmembrane protein 212 |
| TMEM57 | transmembrane protein 57 |
| TNS2 | tensin 2 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM36 | tripartite motif containing 36 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TUBA3C | tubulin, alpha 3c |
| UNC119 | unc-119 homolog (C. elegans) |
| USP20 | ubiquitin specific peptidase 20 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF282 | zinc finger protein 282 |
| ZNF324 | zinc finger protein 324 |
| ZNF551 | zinc finger protein 551 |
