metitepine-6312 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the metitepine-6312 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ALAD aminolevulinate dehydratase
AOC2 amine oxidase, copper containing 2 (retina-specific)
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP9A ATPase, class II, type 9A
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C9ORF156 chromosome 9 open reading frame 156
CCDC88A coiled-coil domain containing 88A
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CNTD2 cyclin N-terminal domain containing 2
DMTN dematin actin binding protein
DNAH7 dynein, axonemal, heavy chain 7
DZIP3 DAZ interacting zinc finger protein 3
EML2 echinoderm microtubule associated protein like 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FCMR Fc fragment of IgM receptor
FLT1 fms-related tyrosine kinase 1
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FXYD3 FXYD domain containing ion transport regulator 3
GOLGA2 golgin A2
GPR17 G protein-coupled receptor 17
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTCD glutathione S-transferase, C-terminal domain containing
HAMP hepcidin antimicrobial peptide
HCFC1 host cell factor C1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HRG histidine-rich glycoprotein
IDS iduronate 2-sulfatase
IFI6 interferon, alpha-inducible protein 6
JRK Jrk homolog (mouse)
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT15 keratin 15, type I
KRT8P12 keratin 8 pseudogene 12
LIG4 ligase IV, DNA, ATP-dependent
LMTK1 lemur tail kinase 1
LRRK1 leucine-rich repeat kinase 1
MAT2A methionine adenosyltransferase II, alpha
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDFI MyoD family inhibitor
MEF2D myocyte enhancer factor 2D
METTL7A methyltransferase like 7A
MIER2 mesoderm induction early response 1, family member 2
MRC2 mannose receptor, C type 2
MXD3 MAX dimerization protein 3
MYBPC3 myosin binding protein C, cardiac
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NKX3-2 NK3 homeobox 2
NME5 NME/NM23 family member 5
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRSN2 neurensin 2
NRXN3 neurexin 3
NT5M 5',3'-nucleotidase, mitochondrial
OVGP1 oviductal glycoprotein 1, 120kDa
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PALM paralemmin
PAOX polyamine oxidase (exo-N4-amino)
PDE4DIP phosphodiesterase 4D interacting protein
PLAGL2 pleiomorphic adenoma gene-like 2
PPARD peroxisome proliferator-activated receptor delta
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRICKLE3 prickle homolog 3 (Drosophila)
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTK6 protein tyrosine kinase 6
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PVT1 Pvt1 oncogene (non-protein coding)
RAB31 RAB31, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANGAP1 Ran GTPase activating protein 1
RBM19 RNA binding motif protein 19
RPH3AL rabphilin 3A-like (without C2 domains)
RWDD2A RWD domain containing 2A
SARM1 sterile alpha and TIR motif containing 1
SCARB1 scavenger receptor class B, member 1
SETD8 SET domain containing (lysine methyltransferase) 8
SKIL SKI-like proto-oncogene
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SPRR1A small proline-rich protein 1A
STEAP4 STEAP family member 4
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D17 TBC1 domain family, member 17
TBXA2R thromboxane A2 receptor
TECPR2 tectonin beta-propeller repeat containing 2
TGFB1 transforming growth factor, beta 1
TMEM53 transmembrane protein 53
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM45 tripartite motif containing 45
TUBGCP2 tubulin, gamma complex associated protein 2
VWA5A von Willebrand factor A domain containing 5A
WSB1 WD repeat and SOCS box containing 1
WWOX WW domain containing oxidoreductase
ZC3H7B zinc finger CCCH-type containing 7B
ZER1 zyg-11 related, cell cycle regulator
ZNF467 zinc finger protein 467
ZNF589 zinc finger protein 589
ZNF606 zinc finger protein 606

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ACAD10 acyl-CoA dehydrogenase family, member 10
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANOS1 anosmin 1
ATF7IP2 activating transcription factor 7 interacting protein 2
AUH AU RNA binding protein/enoyl-CoA hydratase
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BPGM 2,3-bisphosphoglycerate mutase
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF115 chromosome 1 open reading frame 115
C1QTNF1 C1q and tumor necrosis factor related protein 1
C4ORF29 chromosome 4 open reading frame 29
CCDC25 coiled-coil domain containing 25
CDH3 cadherin 3, type 1, P-cadherin (placental)
CHKB choline kinase beta
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DET1 de-etiolated homolog 1 (Arabidopsis)
EDC3 enhancer of mRNA decapping 3
EHD3 EH-domain containing 3
ELOVL4 ELOVL fatty acid elongase 4
EN2 engrailed homeobox 2
EPHA4 EPH receptor A4
EVL Enah/Vasp-like
FA2H fatty acid 2-hydroxylase
FER fer (fps/fes related) tyrosine kinase
FLCN folliculin
FOXK2 forkhead box K2
FUZ fuzzy planar cell polarity protein
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HIST1H1D histone cluster 1, H1d
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HOXA2 homeobox A2
HOXC4 homeobox C4
IRF6 interferon regulatory factor 6
ITPKC inositol-trisphosphate 3-kinase C
LNPEP leucyl/cystinyl aminopeptidase
LPPR4 lipid phosphate phosphatase-related protein type 4
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LYPLA2P1 lysophospholipase II pseudogene 1
MAGEF1 melanoma antigen family F1
MAST3 microtubule associated serine/threonine kinase 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPL41 mitochondrial ribosomal protein L41
MRPS18C mitochondrial ribosomal protein S18C
MYO19 myosin XIX
NFS1 NFS1 cysteine desulfurase
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NRTN neurturin
NT5DC3 5'-nucleotidase domain containing 3
ONECUT2 one cut homeobox 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAQR4 progestin and adipoQ receptor family member IV
PDE12 phosphodiesterase 12
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PMM1 phosphomannomutase 1
POM121 POM121 transmembrane nucleoporin
PPL periplakin
PRPH peripherin
PRR15L proline rich 15-like
PTCD2 pentatricopeptide repeat domain 2
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RASA2 RAS p21 protein activator 2
RNF31 ring finger protein 31
S100A9 S100 calcium binding protein A9
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SETD6 SET domain containing 6
SH2D2A SH2 domain containing 2A
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SNTA1 syntrophin, alpha 1
SOX12 SRY (sex determining region Y)-box 12
SPATA2L spermatogenesis associated 2-like
STIM1 stromal interaction molecule 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TIGD6 tigger transposable element derived 6
TMEM2 transmembrane protein 2
TNRC6B trinucleotide repeat containing 6B
TPK1 thiamin pyrophosphokinase 1
TUBA3C tubulin, alpha 3c
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
URM1 ubiquitin related modifier 1
WDR19 WD repeat domain 19
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF215 zinc finger protein 215
ZNF230 zinc finger protein 230
ZNF253 zinc finger protein 253
ZNF282 zinc finger protein 282
ZNF34 zinc finger protein 34
ZNF358 zinc finger protein 358
ZNF442 zinc finger protein 442
ZNF675 zinc finger protein 675
ZNF84 zinc finger protein 84