| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the metixene-2451 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK4 | aarF domain containing kinase 4 |
| ADCY9 | adenylate cyclase 9 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 |
| AURKA | aurora kinase A |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD22 | CD22 molecule |
| CDH8 | cadherin 8, type 2 |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CYB5A | cytochrome b5 type A (microsomal) |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DIAPH2 | diaphanous-related formin 2 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| EED | embryonic ectoderm development |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| EPS8L1 | EPS8-like 1 |
| EWSR1 | EWS RNA-binding protein 1 |
| FADS3 | fatty acid desaturase 3 |
| FCAR | Fc fragment of IgA receptor |
| FER | fer (fps/fes related) tyrosine kinase |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLOT1 | flotillin 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| HIST1H2BC | histone cluster 1, H2bc |
| HSF2 | heat shock transcription factor 2 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IFT27 | intraflagellar transport 27 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA1109 | KIAA1109 |
| KLF6 | Kruppel-like factor 6 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMAN1 | lectin, mannose-binding, 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAOA | monoamine oxidase A |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MED16 | mediator complex subunit 16 |
| MFAP3 | microfibrillar-associated protein 3 |
| MPDZ | multiple PDZ domain protein |
| MTCP1 | mature T-cell proliferation 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NEBL | nebulette |
| NEK9 | NIMA-related kinase 9 |
| NLRP1 | NLR family, pyrin domain containing 1 |
| NOTCH2 | notch 2 |
| NOX1 | NADPH oxidase 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
| NUP214 | nucleoporin 214kDa |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RBPMS | RNA binding protein with multiple splicing |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RPGRIP1L | RPGRIP1-like |
| S100A13 | S100 calcium binding protein A13 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TAT | tyrosine aminotransferase |
| TBCD | tubulin folding cofactor D |
| TEX15 | testis expressed 15 |
| TEX40 | testis expressed 40 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TRIM23 | tripartite motif containing 23 |
| TRIM25 | tripartite motif containing 25 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TWF1 | twinfilin actin binding protein 1 |
| ULBP2 | UL16 binding protein 2 |
| ZNF24 | zinc finger protein 24 |
| ZNF280A | zinc finger protein 280A |
| ZNF675 | zinc finger protein 675 |
| Symbol | Name |
|---|---|
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AEN | apoptosis enhancing nuclease |
| AMH | anti-Mullerian hormone |
| ANKRD55 | ankyrin repeat domain 55 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APOL6 | apolipoprotein L, 6 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC176 | coiled-coil domain containing 176 |
| CCDC71 | coiled-coil domain containing 71 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDCP1 | CUB domain containing protein 1 |
| CES3 | carboxylesterase 3 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DOCK4 | dedicator of cytokinesis 4 |
| DPEP2 | dipeptidase 2 |
| EGR2 | early growth response 2 |
| ENO3 | enolase 3 (beta, muscle) |
| FAM102A | family with sequence similarity 102, member A |
| FAM63A | family with sequence similarity 63, member A |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GAMT | guanidinoacetate N-methyltransferase |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPX2 | glutathione peroxidase 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HOXA5 | homeobox A5 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| IPO4 | importin 4 |
| IQCG | IQ motif containing G |
| IRS1 | insulin receptor substrate 1 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KIAA0754 | KIAA0754 |
| KLHL21 | kelch-like family member 21 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC257152 | uncharacterized LOC257152 |
| LRRC20 | leucine rich repeat containing 20 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MARCKSL1 | MARCKS-like 1 |
| MKS1 | Meckel syndrome, type 1 |
| MRAS | muscle RAS oncogene homolog |
| MREG | melanoregulin |
| NIPAL2 | NIPA-like domain containing 2 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PNOC | prepronociceptin |
| POMZP3 | POM121 and ZP3 fusion |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIN1 | Ras and Rab interactor 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SH2D4A | SH2 domain containing 4A |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SV2A | synaptic vesicle glycoprotein 2A |
| TERT | telomerase reverse transcriptase |
| TMEM206 | transmembrane protein 206 |
| TNRC6B | trinucleotide repeat containing 6B |
| TPCN1 | two pore segment channel 1 |
| TRAIP | TRAF interacting protein |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TSPAN2 | tetraspanin 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| VEGFB | vascular endothelial growth factor B |
| WDR62 | WD repeat domain 62 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZNF493 | zinc finger protein 493 |
