| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the metixene-3313 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM8 | ADAM metallopeptidase domain 8 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARTN | artemin |
| ATM | ATM serine/threonine kinase |
| BCORL1 | BCL6 corepressor-like 1 |
| CD200 | CD200 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLDN11 | claudin 11 |
| CLEC3B | C-type lectin domain family 3, member B |
| CNTNAP1 | contactin associated protein 1 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CTBP2 | C-terminal binding protein 2 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CUL9 | cullin 9 |
| CYHR1 | cysteine/histidine-rich 1 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease |
| DRD2 | dopamine receptor D2 |
| DUSP4 | dual specificity phosphatase 4 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EVI5 | ecotropic viral integration site 5 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| EZR | ezrin |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOXG1 | forkhead box G1 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRPR | gastrin-releasing peptide receptor |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HBEGF | heparin-binding EGF-like growth factor |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HFE | hemochromatosis |
| HMOX1 | heme oxygenase 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| KIAA1107 | KIAA1107 |
| KLHL24 | kelch-like family member 24 |
| LEPR | leptin receptor |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LRRC15 | leucine rich repeat containing 15 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MED18 | mediator complex subunit 18 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCOR2 | nuclear receptor corepressor 2 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NPC1 | Niemann-Pick disease, type C1 |
| NPY4R | neuropeptide Y receptor Y4 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PXN | paxillin |
| RAB6B | RAB6B, member RAS oncogene family |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHOH | ras homolog family member H |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPL26 | ribosomal protein L26 |
| RSU1 | Ras suppressor protein 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SIRT5 | sirtuin 5 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SPRR1B | small proline-rich protein 1B |
| SRP72 | signal recognition particle 72kDa |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TMEM63A | transmembrane protein 63A |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTC39A | tetratricopeptide repeat domain 39A |
| TUBA3C | tubulin, alpha 3c |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF287 | zinc finger protein 287 |
| ZNF419 | zinc finger protein 419 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CBR4 | carbonyl reductase 4 |
| CBX4 | chromobox homolog 4 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDK3 | cyclin-dependent kinase 3 |
| CIDEB | cell death-inducing DFFA-like effector b |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORT | cortistatin |
| CRYZ | crystallin, zeta (quinone reductase) |
| CTSF | cathepsin F |
| DAGLA | diacylglycerol lipase, alpha |
| DEAF1 | DEAF1 transcription factor |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DOCK1 | dedicator of cytokinesis 1 |
| DVL1 | dishevelled segment polarity protein 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM184A | family with sequence similarity 184, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO22 | F-box protein 22 |
| FBXO31 | F-box protein 31 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ22184 | |
| FOCAD | focadhesin |
| FOXC1 | forkhead box C1 |
| FPGS | folylpolyglutamate synthase |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GMPR | guanosine monophosphate reductase |
| H1F0 | H1 histone family, member 0 |
| HDAC5 | histone deacetylase 5 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H2AM | histone cluster 1, H2am |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXC5 | homeobox C5 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| HYI | hydroxypyruvate isomerase (putative) |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT54 | intraflagellar transport 54 |
| KIF16B | kinesin family member 16B |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| METTL16 | methyltransferase like 16 |
| MOSPD3 | motile sperm domain containing 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MXD3 | MAX dimerization protein 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NPTX1 | neuronal pentraxin I |
| NPY1R | neuropeptide Y receptor Y1 |
| OLFML2A | olfactomedin-like 2A |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PMM1 | phosphomannomutase 1 |
| PP14571 | uncharacterized LOC100130449 |
| PRR4 | proline rich 4 (lacrimal) |
| PVRL3 | poliovirus receptor-related 3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SECTM1 | secreted and transmembrane 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SETD1A | SET domain containing 1A |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SHPK | sedoheptulokinase |
| SIX1 | SIX homeobox 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAOK1 | TAO kinase 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM209 | transmembrane protein 209 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSPAN5 | tetraspanin 5 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR91 | WD repeat domain 91 |
| WLS | wntless Wnt ligand secretion mediator |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF365 | zinc finger protein 365 |
| ZNF557 | zinc finger protein 557 |
| ZNF747 | zinc finger protein 747 |
