| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the metixene-5018 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAM17 | ADAM metallopeptidase domain 17 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| ATXN1 | ataxin 1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CD44 | CD44 molecule (Indian blood group) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNTN1 | contactin 1 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR3 | early growth response 3 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ETV5 | ets variant 5 |
| FAM46C | family with sequence similarity 46, member C |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLRX | glutaredoxin (thioltransferase) |
| HBP1 | HMG-box transcription factor 1 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IL6R | interleukin 6 receptor |
| ING1 | inhibitor of growth family, member 1 |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITCH | itchy E3 ubiquitin protein ligase |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KLF2 | Kruppel-like factor 2 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MDM4 | MDM4, p53 regulator |
| MMP13 | matrix metallopeptidase 13 |
| MT1F | metallothionein 1F |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDRG1 | N-myc downstream regulated 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLAUR | plasminogen activator, urokinase receptor |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PSPH | phosphoserine phosphatase |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMAD3 | SMAD family member 3 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRCAP | Snf2-related CREBBP activator protein |
| STX3 | syntaxin 3 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TLR2 | toll-like receptor 2 |
| TMEM2 | transmembrane protein 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIM2 | tripartite motif containing 2 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSC22D3 | TSC22 domain family, member 3 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| ULBP2 | UL16 binding protein 2 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF516 | zinc finger protein 516 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CEP97 | centrosomal protein 97kDa |
| CHMP6 | charged multivesicular body protein 6 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CTPS1 | CTP synthase 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DUSP2 | dual specificity phosphatase 2 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFNA3 | ephrin-A3 |
| EN2 | engrailed homeobox 2 |
| EXO5 | exonuclease 5 |
| FAM120C | family with sequence similarity 120C |
| FAM155A | family with sequence similarity 155, member A |
| FAM184A | family with sequence similarity 184, member A |
| FBXO4 | F-box protein 4 |
| FBXO46 | F-box protein 46 |
| FOXI1 | forkhead box I1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPR21 | G protein-coupled receptor 21 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFT140 | intraflagellar transport 140 |
| IFT54 | intraflagellar transport 54 |
| IQCG | IQ motif containing G |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KIAA0319L | KIAA0319-like |
| KIF13A | kinesin family member 13A |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC20 | leucine rich repeat containing 20 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| METTL8 | methyltransferase like 8 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MSX1 | msh homeobox 1 |
| MYOZ3 | myozenin 3 |
| NISCH | nischarin |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| OLFML2A | olfactomedin-like 2A |
| OPN3 | opsin 3 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PODXL2 | podocalyxin-like 2 |
| POLL | polymerase (DNA directed), lambda |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PTDSS2 | phosphatidylserine synthase 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A9 | S100 calcium binding protein A9 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SKI | SKI proto-oncogene |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SNTA1 | syntrophin, alpha 1 |
| SPAG4 | sperm associated antigen 4 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| THBS3 | thrombospondin 3 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM164 | transmembrane protein 164 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM45 | tripartite motif containing 45 |
| TTC4 | tetratricopeptide repeat domain 4 |
| USB1 | U6 snRNA biogenesis 1 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) |
| WBSCR16 | Williams-Beuren syndrome chromosome region 16 |
| XYLT2 | xylosyltransferase II |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
