| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the metixene-6672 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACHE | acetylcholinesterase (Yt blood group) |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGRD2 | adhesion G protein-coupled receptor D2 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AMOT | angiomotin |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CRLF2 | cytokine receptor-like factor 2 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DCN | decorin |
| DENND3 | DENN/MADD domain containing 3 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP5 | dual specificity phosphatase 5 |
| EDN1 | endothelin 1 |
| EPHB1 | EPH receptor B1 |
| FCAR | Fc fragment of IgA receptor |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GLRA3 | glycine receptor, alpha 3 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GSN | gelsolin |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| IGHD | immunoglobulin heavy constant delta |
| IL6 | interleukin 6 |
| INSIG1 | insulin induced gene 1 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITGB8 | integrin, beta 8 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIR2DL4 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 |
| KLF13 | Kruppel-like factor 13 |
| KLHL24 | kelch-like family member 24 |
| KRT24 | keratin 24, type I |
| LAMA4 | laminin, alpha 4 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LOX | lysyl oxidase |
| LRRN3 | leucine rich repeat neuronal 3 |
| MEP1B | meprin A, beta |
| MSR1 | macrophage scavenger receptor 1 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDNF | neuron-derived neurotrophic factor |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NRXN3 | neurexin 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDH9 | protocadherin 9 |
| PCNX | pecanex homolog (Drosophila) |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PENK | proenkephalin |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| RFPL1 | ret finger protein-like 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RND1 | Rho family GTPase 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SASH3 | SAM and SH3 domain containing 3 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLC6A16 | solute carrier family 6, member 16 |
| SMAD7 | SMAD family member 7 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STC2 | stanniocalcin 2 |
| TAPBP | TAP binding protein (tapasin) |
| TFF3 | trefoil factor 3 (intestinal) |
| TGFB2 | transforming growth factor, beta 2 |
| THOC5 | THO complex 5 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMEM40 | transmembrane protein 40 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM29 | tripartite motif containing 29 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| VGLL3 | vestigial-like family member 3 |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) |
| ZNF165 | zinc finger protein 165 |
| ZNF500 | zinc finger protein 500 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| AEN | apoptosis enhancing nuclease |
| ANOS1 | anosmin 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BMP15 | bone morphogenetic protein 15 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CBX8 | chromobox homolog 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNN2 | calponin 2 |
| CRYGC | crystallin, gamma C |
| CST1 | cystatin SN |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DSPP | dentin sialophosphoprotein |
| ECM1 | extracellular matrix protein 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EN2 | engrailed homeobox 2 |
| EPN3 | epsin 3 |
| ERF | Ets2 repressor factor |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FANCC | Fanconi anemia, complementation group C |
| FBRS | fibrosin |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FHOD3 | formin homology 2 domain containing 3 |
| FKBP5 | FK506 binding protein 5 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GAS8 | growth arrest-specific 8 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3F | histone cluster 1, H3f |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXA1 | homeobox A1 |
| IL36RN | interleukin 36 receptor antagonist |
| IL7 | interleukin 7 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IREB2 | iron-responsive element binding protein 2 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KLK7 | kallikrein-related peptidase 7 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MED15 | mediator complex subunit 15 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MMP3 | matrix metallopeptidase 3 |
| MRAS | muscle RAS oncogene homolog |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NRTN | neurturin |
| ORC1 | origin recognition complex, subunit 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PC | pyruvate carboxylase |
| PICK1 | protein interacting with PRKCA 1 |
| PLD2 | phospholipase D2 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PROL1 | proline rich, lacrimal 1 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RNF2 | ring finger protein 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMA4 | glucuronidase, beta pseudogene |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAOK1 | TAO kinase 1 |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TENM4 | teneurin transmembrane protein 4 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMC7 | transmembrane channel-like 7 |
| TMEM180 | transmembrane protein 180 |
| TMSB15A | thymosin beta 15a |
| TRAF2 | TNF receptor-associated factor 2 |
| TXK | TXK tyrosine kinase |
| UGT8 | UDP glycosyltransferase 8 |
| VASH1 | vasohibin 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF239 | zinc finger protein 239 |
