| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the metolazone-1514 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| AIF1 | allograft inflammatory factor 1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ANKRD12 | ankyrin repeat domain 12 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BIN1 | bridging integrator 1 |
| BMP5 | bone morphogenetic protein 5 |
| BTBD7 | BTB (POZ) domain containing 7 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CDC25A | cell division cycle 25A |
| CEP152 | centrosomal protein 152kDa |
| CEP85 | centrosomal protein 85kDa |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| COL6A1 | collagen, type VI, alpha 1 |
| CRMP1 | collapsin response mediator protein 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| EFNB3 | ephrin-B3 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EPHB2 | EPH receptor B2 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| EXO5 | exonuclease 5 |
| EZR | ezrin |
| FAM212B | family with sequence similarity 212, member B |
| FAM214B | family with sequence similarity 214, member B |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FGF3 | fibroblast growth factor 3 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FOXG1 | forkhead box G1 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXB3 | homeobox B3 |
| HOXC5 | homeobox C5 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL6ST | interleukin 6 signal transducer |
| KCNIP1 | Kv channel interacting protein 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA0319L | KIAA0319-like |
| LAMC2 | laminin, gamma 2 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MALL | mal, T-cell differentiation protein-like |
| MED25 | mediator complex subunit 25 |
| MTA1 | metastasis associated 1 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MYO15B | myosin XVB |
| NPY2R | neuropeptide Y receptor Y2 |
| NRSN2 | neurensin 2 |
| OGFR | opioid growth factor receptor |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PCNX | pecanex homolog (Drosophila) |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLK3 | polo-like kinase 3 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF17 | ring finger protein 17 |
| RUNDC3A | RUN domain containing 3A |
| S100A8 | S100 calcium binding protein A8 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STXBP5L | syntaxin binding protein 5-like |
| SUMO1 | small ubiquitin-like modifier 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYNJ2 | synaptojanin 2 |
| TAOK2 | TAO kinase 2 |
| TH | tyrosine hydroxylase |
| TIMELESS | timeless circadian clock |
| TRD | T cell receptor delta locus |
| TUBA3C | tubulin, alpha 3c |
| TXNL4A | thioredoxin-like 4A |
| USB1 | U6 snRNA biogenesis 1 |
| UTRN | utrophin |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| ZBTB14 | zinc finger and BTB domain containing 14 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZIC3 | Zic family member 3 |
| ZNF500 | zinc finger protein 500 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AEN | apoptosis enhancing nuclease |
| ALDOC | aldolase C, fructose-bisphosphate |
| ALPK1 | alpha-kinase 1 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARMC4 | armadillo repeat containing 4 |
| ARRB1 | arrestin, beta 1 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAPRIN2 | caprin family member 2 |
| CBX7 | chromobox homolog 7 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC85C | coiled-coil domain containing 85C |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CFD | complement factor D (adipsin) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLSPN | claspin |
| CLSTN2 | calsyntenin 2 |
| CORO7 | coronin 7 |
| CORT | cortistatin |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CST6 | cystatin E/M |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| GAMT | guanidinoacetate N-methyltransferase |
| GRB7 | growth factor receptor-bound protein 7 |
| GRPR | gastrin-releasing peptide receptor |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BJ | histone cluster 1, H2bj |
| IPO8 | importin 8 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA10 | integrin, alpha 10 |
| KIFC1 | kinesin family member C1 |
| KLHL26 | kelch-like family member 26 |
| KRT13 | keratin 13, type I |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC257152 | uncharacterized LOC257152 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MCOLN3 | mucolipin 3 |
| MKS1 | Meckel syndrome, type 1 |
| MMP2 | matrix metallopeptidase 2 |
| MSI1 | musashi RNA-binding protein 1 |
| MTRF1 | mitochondrial translational release factor 1 |
| MUC3A | mucin 3A, cell surface associated |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB30 | RAB30, member RAS oncogene family |
| RANBP17 | RAN binding protein 17 |
| RGS19 | regulator of G-protein signaling 19 |
| RIN2 | Ras and Rab interactor 2 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUFY2 | RUN and FYVE domain containing 2 |
| S100A4 | S100 calcium binding protein A4 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SDC3 | syndecan 3 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC16A6 | solute carrier family 16, member 6 |
| SMA4 | glucuronidase, beta pseudogene |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TADA2A | transcriptional adaptor 2A |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TCTN2 | tectonic family member 2 |
| THBS3 | thrombospondin 3 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TLR5 | toll-like receptor 5 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM104 | transmembrane protein 104 |
| TMEM184C | transmembrane protein 184C |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIM25 | tripartite motif containing 25 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSPAN5 | tetraspanin 5 |
| UBQLN4 | ubiquilin 4 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VASH1 | vasohibin 1 |
| WDR25 | WD repeat domain 25 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZNF276 | zinc finger protein 276 |
| ZNF492 | zinc finger protein 492 |
