| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the metolazone-1932 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARL4C | ADP-ribosylation factor-like 4C |
| AVPR1B | arginine vasopressin receptor 1B |
| BCL9 | B-cell CLL/lymphoma 9 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CAPN2 | calpain 2, (m/II) large subunit |
| CD47 | CD47 molecule |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDHR2 | cadherin-related family member 2 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CENPN | centromere protein N |
| CHMP1A | charged multivesicular body protein 1A |
| CIRBP | cold inducible RNA binding protein |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLDN15 | claudin 15 |
| COPS7B | COP9 signalosome subunit 7B |
| CYB561 | cytochrome b561 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 |
| DENND2A | DENN/MADD domain containing 2A |
| DLL3 | delta-like 3 (Drosophila) |
| DXO | decapping exoribonuclease |
| EFNA3 | ephrin-A3 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| EPHA2 | EPH receptor A2 |
| ERCC2 | excision repair cross-complementation group 2 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| GFER | growth factor, augmenter of liver regeneration |
| GPC1 | glypican 1 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GRK6 | G protein-coupled receptor kinase 6 |
| H2AFY2 | H2A histone family, member Y2 |
| HIST1H1D | histone cluster 1, H1d |
| HSF1 | heat shock transcription factor 1 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KHSRP | KH-type splicing regulatory protein |
| KIAA0141 | KIAA0141 |
| KLHDC10 | kelch domain containing 10 |
| KLHL24 | kelch-like family member 24 |
| LMF2 | lipase maturation factor 2 |
| LPIN1 | lipin 1 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LRRC41 | leucine rich repeat containing 41 |
| LSR | lipolysis stimulated lipoprotein receptor |
| MED27 | mediator complex subunit 27 |
| MRPL57 | mitochondrial ribosomal protein L57 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| MYL9 | myosin, light chain 9, regulatory |
| MZF1 | myeloid zinc finger 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NRSN2 | neurensin 2 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PDLIM4 | PDZ and LIM domain 4 |
| PIGR | polymeric immunoglobulin receptor |
| PLIN2 | perilipin 2 |
| PLXNA3 | plexin A3 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PRKCSH | protein kinase C substrate 80K-H |
| PTOV1 | prostate tumor overexpressed 1 |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RBM47 | RNA binding motif protein 47 |
| RGS3 | regulator of G-protein signaling 3 |
| RPS21 | ribosomal protein S21 |
| SAMHD1 | SAM domain and HD domain 1 |
| SEPHS1 | selenophosphate synthetase 1 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SNPH | syntaphilin |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SQLE | squalene epoxidase |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| TEAD3 | TEA domain family member 3 |
| TMEM161A | transmembrane protein 161A |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRAPPC12 | trafficking protein particle complex 12 |
| USB1 | U6 snRNA biogenesis 1 |
| WIZ | widely interspaced zinc finger motifs |
| WSCD1 | WSC domain containing 1 |
| WWC2 | WW and C2 domain containing 2 |
| YIPF2 | Yip1 domain family, member 2 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNF408 | zinc finger protein 408 |
| ZNF518A | zinc finger protein 518A |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| AHR | aryl hydrocarbon receptor |
| AIDA | axin interactor, dorsalization associated |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| ARMT1 | acidic residue methyltransferase 1 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C1ORF27 | chromosome 1 open reading frame 27 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CDC73 | cell division cycle 73 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| CPOX | coproporphyrinogen oxidase |
| CRY1 | cryptochrome circadian clock 1 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| DCK | deoxycytidine kinase |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DOCK1 | dedicator of cytokinesis 1 |
| E2F8 | E2F transcription factor 8 |
| ECT2 | epithelial cell transforming 2 |
| EIF1B | eukaryotic translation initiation factor 1B |
| EMC2 | ER membrane protein complex subunit 2 |
| ERBB2IP | erbb2 interacting protein |
| ERCC5 | excision repair cross-complementation group 5 |
| EXOC5 | exocyst complex component 5 |
| FAM188A | family with sequence similarity 188, member A |
| FAM3C | family with sequence similarity 3, member C |
| FBXO5 | F-box protein 5 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| FZD6 | frizzled class receptor 6 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HAS2 | hyaluronan synthase 2 |
| IFNA17 | interferon, alpha 17 |
| IL18 | interleukin 18 |
| INTS12 | integrator complex subunit 12 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KCTD9 | potassium channel tetramerization domain containing 9 |
| KIAA0753 | KIAA0753 |
| LACTB2 | lactamase, beta 2 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LYRM2 | LYR motif containing 2 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MED4 | mediator complex subunit 4 |
| METTL18 | methyltransferase like 18 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MRFAP1L1 | Morf4 family associated protein 1-like 1 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NFS1 | NFS1 cysteine desulfurase |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NUCB2 | nucleobindin 2 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PLA2G12A | phospholipase A2, group XIIA |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma |
| PRPF38B | pre-mRNA processing factor 38B |
| PSPH | phosphoserine phosphatase |
| PTX3 | pentraxin 3, long |
| RAD21 | RAD21 homolog (S. pombe) |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RINT1 | RAD50 interactor 1 |
| RNF11 | ring finger protein 11 |
| RPAP3 | RNA polymerase II associated protein 3 |
| RPE | ribulose-5-phosphate-3-epimerase |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SP3 | Sp3 transcription factor |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TCEAL4 | transcription elongation factor A (SII)-like 4 |
| TOP2B | topoisomerase (DNA) II beta 180kDa |
| TP53BP2 | tumor protein p53 binding protein 2 |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UBA2 | ubiquitin-like modifier activating enzyme 2 |
| UBA5 | ubiquitin-like modifier activating enzyme 5 |
| UFM1 | ubiquitin-fold modifier 1 |
| UFSP2 | UFM1-specific peptidase 2 |
| USP32 | ubiquitin specific peptidase 32 |
| USP6 | ubiquitin specific peptidase 6 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF611 | zinc finger protein 611 |
