| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the metolazone-2014 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AFF2 | AF4/FMR2 family, member 2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ARRB2 | arrestin, beta 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| AVPR1B | arginine vasopressin receptor 1B |
| BCL7A | B-cell CLL/lymphoma 7A |
| C4BPA | complement component 4 binding protein, alpha |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBY1 | chibby homolog 1 (Drosophila) |
| CD82 | CD82 molecule |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FAM102A | family with sequence similarity 102, member A |
| FAM153A | family with sequence similarity 153, member A |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FZD2 | frizzled class receptor 2 |
| GCKR | glucokinase (hexokinase 4) regulator |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPR12 | G protein-coupled receptor 12 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4J | histone cluster 1, H4j |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-F | major histocompatibility complex, class I, F |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HTRA2 | HtrA serine peptidase 2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IFNA17 | interferon, alpha 17 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IL1R2 | interleukin 1 receptor, type II |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa |
| ITGA7 | integrin, alpha 7 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLF6 | Kruppel-like factor 6 |
| KLHL18 | kelch-like family member 18 |
| LAMA4 | laminin, alpha 4 |
| LPAR2 | lysophosphatidic acid receptor 2 |
| LRRC14 | leucine rich repeat containing 14 |
| LTB4R | leukotriene B4 receptor |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAML3 | mastermind-like 3 (Drosophila) |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| METTL7A | methyltransferase like 7A |
| MMP25 | matrix metallopeptidase 25 |
| MORC2 | MORC family CW-type zinc finger 2 |
| MSH3 | mutS homolog 3 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MST1 | macrophage stimulating 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MZF1 | myeloid zinc finger 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLCB4 | phospholipase C, beta 4 |
| POLG | polymerase (DNA directed), gamma |
| PRLH | prolactin releasing hormone |
| R3HDM1 | R3H domain containing 1 |
| RBFA | ribosome binding factor A (putative) |
| RPL10 | ribosomal protein L10 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SH2D3A | SH2 domain containing 3A |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SPHK1 | sphingosine kinase 1 |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 |
| SRGN | serglycin |
| ST7 | suppression of tumorigenicity 7 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| STRN4 | striatin, calmodulin binding protein 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TARDBP | TAR DNA binding protein |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TERT | telomerase reverse transcriptase |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THEM6 | thioesterase superfamily member 6 |
| THOC6 | THO complex 6 |
| TUBGCP2 | tubulin, gamma complex associated protein 2 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| XAF1 | XIAP associated factor 1 |
| ZFYVE26 | zinc finger, FYVE domain containing 26 |
| ZNF224 | zinc finger protein 224 |
| ZNF512B | zinc finger protein 512B |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD4 | abhydrolase domain containing 4 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| ADAM9 | ADAM metallopeptidase domain 9 |
| ANKRD40 | ankyrin repeat domain 40 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 |
| ASNSD1 | asparagine synthetase domain containing 1 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATF3 | activating transcription factor 3 |
| ATG7 | autophagy related 7 |
| ATXN2 | ataxin 2 |
| BCL10 | B-cell CLL/lymphoma 10 |
| BCL7C | B-cell CLL/lymphoma 7C |
| BSG | basigin (Ok blood group) |
| C1ORF216 | chromosome 1 open reading frame 216 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CCDC53 | coiled-coil domain containing 53 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A |
| CDCA8 | cell division cycle associated 8 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CLDND1 | claudin domain containing 1 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| COMMD10 | COMM domain containing 10 |
| COMMD3 | COMM domain containing 3 |
| COMMD8 | COMM domain containing 8 |
| CPOX | coproporphyrinogen oxidase |
| CRIPT | cysteine-rich PDZ-binding protein |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CYCS | cytochrome c, somatic |
| DDHD2 | DDHD domain containing 2 |
| DENND1A | DENN/MADD domain containing 1A |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| DYNLL1 | dynein, light chain, LC8-type 1 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| ERF | Ets2 repressor factor |
| EXO1 | exonuclease 1 |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FKBP3 | FK506 binding protein 3, 25kDa |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HEBP1 | heme binding protein 1 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HILPDA | hypoxia inducible lipid droplet-associated |
| IL4R | interleukin 4 receptor |
| INO80D | INO80 complex subunit D |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| ITGAV | integrin, alpha V |
| KIAA0753 | KIAA0753 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LIMA1 | LIM domain and actin binding 1 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| METTL18 | methyltransferase like 18 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MRPL19 | mitochondrial ribosomal protein L19 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDRG1 | N-myc downstream regulated 1 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCTP | phosphatidylcholine transfer protein |
| PEPD | peptidase D |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma |
| PKN1 | protein kinase N1 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RINT1 | RAD50 interactor 1 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SERINC1 | serine incorporator 1 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SMNDC1 | survival motor neuron domain containing 1 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TBCC | tubulin folding cofactor C |
| TBCCD1 | TBCC domain containing 1 |
| TK1 | thymidine kinase 1, soluble |
| TMEM135 | transmembrane protein 135 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRMT61B | tRNA methyltransferase 61B |
| TSPAN32 | tetraspanin 32 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) |
| USB1 | U6 snRNA biogenesis 1 |
| VLDLR | very low density lipoprotein receptor |
| WDR18 | WD repeat domain 18 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 |
| ZNF217 | zinc finger protein 217 |
| ZNF408 | zinc finger protein 408 |
