| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the metolazone-5392 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| AFF1 | AF4/FMR2 family, member 1 |
| AIRE | autoimmune regulator |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCHCR1 | coiled-coil alpha-helical rod protein 1 |
| CD47 | CD47 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CDK18 | cyclin-dependent kinase 18 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| COMMD4 | COMM domain containing 4 |
| COMT | catechol-O-methyltransferase |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CUL4B | cullin 4B |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DESI2 | desumoylating isopeptidase 2 |
| DMTN | dematin actin binding protein |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EFCAB11 | EF-hand calcium binding domain 11 |
| EN2 | engrailed homeobox 2 |
| FBXO11 | F-box protein 11 |
| FBXO41 | F-box protein 41 |
| FFAR2 | free fatty acid receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| GH1 | growth hormone 1 |
| GHRHR | growth hormone releasing hormone receptor |
| GLS | glutaminase |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR137 | G protein-coupled receptor 137 |
| GRAMD4 | GRAM domain containing 4 |
| HIST1H4F | histone cluster 1, H4f |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IL1R2 | interleukin 1 receptor, type II |
| IL22 | interleukin 22 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KIAA0930 | KIAA0930 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LTC4S | leukotriene C4 synthase |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP4 | microtubule-associated protein 4 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MED16 | mediator complex subunit 16 |
| MR1 | major histocompatibility complex, class I-related |
| MTSS1L | metastasis suppressor 1-like |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| NMT1 | N-myristoyltransferase 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRF1 | nuclear respiratory factor 1 |
| NUP188 | nucleoporin 188kDa |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLK3 | polo-like kinase 3 |
| PLK4 | polo-like kinase 4 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRRC2B | proline-rich coiled-coil 2B |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RHBDD3 | rhomboid domain containing 3 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SECTM1 | secreted and transmembrane 1 |
| SGSM2 | small G protein signaling modulator 2 |
| SIK3 | SIK family kinase 3 |
| SIRT5 | sirtuin 5 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SUMO1 | small ubiquitin-like modifier 1 |
| TBC1D2B | TBC1 domain family, member 2B |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| THRB | thyroid hormone receptor, beta |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TP53I11 | tumor protein p53 inducible protein 11 |
| WAPAL | wings apart-like homolog (Drosophila) |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZIC3 | Zic family member 3 |
| ZNF362 | zinc finger protein 362 |
| ZNF682 | zinc finger protein 682 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| AEBP1 | AE binding protein 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BST2 | bone marrow stromal cell antigen 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CA11 | carbonic anhydrase XI |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC88C | coiled-coil domain containing 88C |
| CES3 | carboxylesterase 3 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLDND1 | claudin domain containing 1 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CTAGE9 | CTAGE family, member 9 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| ELMO3 | engulfment and cell motility 3 |
| EVPL | envoplakin |
| FAM46C | family with sequence similarity 46, member C |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FOXN2 | forkhead box N2 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HOXC5 | homeobox C5 |
| HOXD11 | homeobox D11 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA0125 | KIAA0125 |
| KLF2 | Kruppel-like factor 2 |
| KLK5 | kallikrein-related peptidase 5 |
| MDM4 | MDM4, p53 regulator |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OLFML2A | olfactomedin-like 2A |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PGBD5 | piggyBac transposable element derived 5 |
| PGP | phosphoglycolate phosphatase |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PRODH | proline dehydrogenase (oxidase) 1 |
| RAB3D | RAB3D, member RAS oncogene family |
| RANBP17 | RAN binding protein 17 |
| RANGRF | RAN guanine nucleotide release factor |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SYCP2 | synaptonemal complex protein 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBX19 | T-box 19 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMEM209 | transmembrane protein 209 |
| TMEM242 | transmembrane protein 242 |
| TRAIP | TRAF interacting protein |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP20 | ubiquitin specific peptidase 20 |
| WDR76 | WD repeat domain 76 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF16 | zinc finger protein 16 |
| ZNF205 | zinc finger protein 205 |
| ZNF574 | zinc finger protein 574 |
| ZNF639 | zinc finger protein 639 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
