| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the metolazone-6292 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ATG10 | autophagy related 10 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BMP5 | bone morphogenetic protein 5 |
| CALD1 | caldesmon 1 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COL7A1 | collagen, type VII, alpha 1 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DNAL4 | dynein, axonemal, light chain 4 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| ETNK2 | ethanolamine kinase 2 |
| FBXO21 | F-box protein 21 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GHRH | growth hormone releasing hormone |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GRM1 | glutamate receptor, metabotropic 1 |
| HCFC1 | host cell factor C1 |
| HIC2 | hypermethylated in cancer 2 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HOXB5 | homeobox B5 |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IL1RN | interleukin 1 receptor antagonist |
| ITGB4 | integrin, beta 4 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LMNA | lamin A/C |
| LOC257152 | uncharacterized LOC257152 |
| LRRC75B | leucine rich repeat containing 75B |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MYBPC3 | myosin binding protein C, cardiac |
| MZF1 | myeloid zinc finger 1 |
| NCLN | nicalin |
| NDRG4 | NDRG family member 4 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OTOR | otoraplin |
| PDE11A | phosphodiesterase 11A |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PLAC8 | placenta-specific 8 |
| PLCH1 | phospholipase C, eta 1 |
| PLXNA2 | plexin A2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRSS22 | protease, serine, 22 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RARG | retinoic acid receptor, gamma |
| RGS12 | regulator of G-protein signaling 12 |
| RPL10 | ribosomal protein L10 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAFB2 | scaffold attachment factor B2 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCIN | scinderin |
| SIRAL2 | SIR2 antiphage like 2 |
| SMYD5 | SMYD family member 5 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STAG3 | stromal antigen 3 |
| STX2 | syntaxin 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYMPK | symplekin |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TG | thyroglobulin |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TMSB15A | thymosin beta 15a |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TSSK2 | testis-specific serine kinase 2 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| VARS | valyl-tRNA synthetase |
| WDR76 | WD repeat domain 76 |
| ZNF222 | zinc finger protein 222 |
| ZNF446 | zinc finger protein 446 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BAK1 | BCL2-antagonist/killer 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CCS | copper chaperone for superoxide dismutase |
| CDC37L1 | cell division cycle 37-like 1 |
| CDC73 | cell division cycle 73 |
| CDIP1 | cell death-inducing p53 target 1 |
| CHMP6 | charged multivesicular body protein 6 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CRYBA2 | crystallin, beta A2 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DEPDC1 | DEP domain containing 1 |
| DLL3 | delta-like 3 (Drosophila) |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERCC2 | excision repair cross-complementation group 2 |
| FAM69A | family with sequence similarity 69, member A |
| FER | fer (fps/fes related) tyrosine kinase |
| FXN | frataxin |
| FZD3 | frizzled class receptor 3 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GHR | growth hormone receptor |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| HOXA2 | homeobox A2 |
| HOXB9 | homeobox B9 |
| IFT54 | intraflagellar transport 54 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRF1 | interferon regulatory factor 1 |
| IRF6 | interferon regulatory factor 6 |
| KIAA0513 | KIAA0513 |
| KIAA0753 | KIAA0753 |
| KLF2 | Kruppel-like factor 2 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MOXD1 | monooxygenase, DBH-like 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NECAP2 | NECAP endocytosis associated 2 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| PALMD | palmdelphin |
| PC | pyruvate carboxylase |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PEX13 | peroxisomal biogenesis factor 13 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLA2G15 | phospholipase A2, group XV |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POM121 | POM121 transmembrane nucleoporin |
| PRR3 | proline rich 3 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RNF121 | ring finger protein 121 |
| RNF31 | ring finger protein 31 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCAI | suppressor of cancer cell invasion |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SH2D2A | SH2 domain containing 2A |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC4A1AP | solute carrier family 4 (anion exchanger), member 1, adaptor protein |
| SNIP1 | Smad nuclear interacting protein 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPEG | SPEG complex locus |
| STBD1 | starch binding domain 1 |
| STX4 | syntaxin 4 |
| SYTL2 | synaptotagmin-like 2 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TAOK1 | TAO kinase 1 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TEX40 | testis expressed 40 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM45 | tripartite motif containing 45 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TSPAN15 | tetraspanin 15 |
| TSPAN8 | tetraspanin 8 |
| TTC33 | tetratricopeptide repeat domain 33 |
| ZNF107 | zinc finger protein 107 |
| ZNF197 | zinc finger protein 197 |
| ZNF253 | zinc finger protein 253 |
| ZNF408 | zinc finger protein 408 |
| ZNF816 | zinc finger protein 816 |
