| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the metoprolol-6846 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGFG2 | ArfGAP with FG repeats 2 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| APOE | apolipoprotein E |
| APOM | apolipoprotein M |
| CCDC68 | coiled-coil domain containing 68 |
| CCDC7 | coiled-coil domain containing 7 |
| CD6 | CD6 molecule |
| CDIP1 | cell death-inducing p53 target 1 |
| CLIC2 | chloride intracellular channel 2 |
| CLTA | clathrin, light chain A |
| COL16A1 | collagen, type XVI, alpha 1 |
| COL19A1 | collagen, type XIX, alpha 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DOCK5 | dedicator of cytokinesis 5 |
| DOK4 | docking protein 4 |
| EDN1 | endothelin 1 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GM2A | GM2 ganglioside activator |
| GPATCH4 | G patch domain containing 4 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIST1H1T | histone cluster 1, H1t |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HNMT | histamine N-methyltransferase |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI35 | interferon-induced protein 35 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFNA14 | interferon, alpha 14 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL1B | interleukin 1, beta |
| IL5RA | interleukin 5 receptor, alpha |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| JAM3 | junctional adhesion molecule 3 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KHSRP | KH-type splicing regulatory protein |
| LAMB4 | laminin, beta 4 |
| LAMC2 | laminin, gamma 2 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MED16 | mediator complex subunit 16 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MYL10 | myosin, light chain 10, regulatory |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NRP1 | neuropilin 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PDE12 | phosphodiesterase 12 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDZD2 | PDZ domain containing 2 |
| PIGR | polymeric immunoglobulin receptor |
| PLAA | phospholipase A2-activating protein |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RABGAP1L | RAB GTPase activating protein 1-like |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SDS | serine dehydratase |
| SIPA1 | signal-induced proliferation-associated 1 |
| SIRPA | signal-regulatory protein alpha |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SP110 | SP110 nuclear body protein |
| SPAG8 | sperm associated antigen 8 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TAPBP | TAP binding protein (tapasin) |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFF2 | trefoil factor 2 |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TPMT | thiopurine S-methyltransferase |
| TUBA3C | tubulin, alpha 3c |
| USP2 | ubiquitin specific peptidase 2 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| VPS9D1 | VPS9 domain containing 1 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF484 | zinc finger protein 484 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC9 | coiled-coil domain containing 9 |
| CD302 | CD302 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CFD | complement factor D (adipsin) |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CXADR | coxsackie virus and adenovirus receptor |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOC2A | double C2-like domains, alpha |
| EDC4 | enhancer of mRNA decapping 4 |
| EVPL | envoplakin |
| EXOC6B | exocyst complex component 6B |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FGF23 | fibroblast growth factor 23 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HDAC7 | histone deacetylase 7 |
| HIST1H4D | histone cluster 1, H4d |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IL4R | interleukin 4 receptor |
| INO80D | INO80 complex subunit D |
| IQCG | IQ motif containing G |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KDM7A | lysine (K)-specific demethylase 7A |
| KRT83 | keratin 83, type II |
| LIF | leukemia inhibitory factor |
| LOC390998 | ribosomal protein L10 pseudogene |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MCC | mutated in colorectal cancers |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| NRSN2 | neurensin 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| ONECUT1 | one cut homeobox 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PADI1 | peptidyl arginine deiminase, type I |
| PADI3 | peptidyl arginine deiminase, type III |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLL | polymerase (DNA directed), lambda |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRODH | proline dehydrogenase (oxidase) 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RELN | reelin |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| S100A2 | S100 calcium binding protein A2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SDC3 | syndecan 3 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPRYD7 | SPRY domain containing 7 |
| SSPN | sarcospan |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TAOK1 | TAO kinase 1 |
| TESC | tescalcin |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMC5 | transmembrane channel-like 5 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TSPYL2 | TSPY-like 2 |
| UBQLN4 | ubiquilin 4 |
| USB1 | U6 snRNA biogenesis 1 |
| VN1R1 | vomeronasal 1 receptor 1 |
| XYLT2 | xylosyltransferase II |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZIC3 | Zic family member 3 |
| ZNF701 | zinc finger protein 701 |
