| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the metrifonate-1675 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACVR1B | activin A receptor, type IB |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATN1 | atrophin 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BBS9 | Bardet-Biedl syndrome 9 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BCL2L2 | BCL2-like 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| CAPN10 | calpain 10 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD6 | CD6 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEP162 | centrosomal protein 162kDa |
| CERS4 | ceramide synthase 4 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CRMP1 | collapsin response mediator protein 1 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DOCK4 | dedicator of cytokinesis 4 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EGFL7 | EGF-like-domain, multiple 7 |
| EGFR | epidermal growth factor receptor |
| ELL | elongation factor RNA polymerase II |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM134B | family with sequence similarity 134, member B |
| FAM46C | family with sequence similarity 46, member C |
| FMO5 | flavin containing monooxygenase 5 |
| FRK | fyn-related Src family tyrosine kinase |
| GM2A | GM2 ganglioside activator |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HDAC11 | histone deacetylase 11 |
| HFE | hemochromatosis |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HOXD9 | homeobox D9 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL11 | interleukin 11 |
| JADE2 | jade family PHD finger 2 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0319L | KIAA0319-like |
| KLF2 | Kruppel-like factor 2 |
| LAMC2 | laminin, gamma 2 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAP1A | microtubule-associated protein 1A |
| MAP1B | microtubule-associated protein 1B |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MR1 | major histocompatibility complex, class I-related |
| MST1 | macrophage stimulating 1 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NMT2 | N-myristoyltransferase 2 |
| NXPH4 | neurexophilin 4 |
| PARD6B | par-6 family cell polarity regulator beta |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDLIM5 | PDZ and LIM domain 5 |
| PLA2G10 | phospholipase A2, group X |
| PLAU | plasminogen activator, urokinase |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRR4 | proline rich 4 (lacrimal) |
| RAD51 | RAD51 recombinase |
| RFK | riboflavin kinase |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SIK3 | SIK family kinase 3 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STAT5B | signal transducer and activator of transcription 5B |
| STS | steroid sulfatase (microsomal), isozyme S |
| TIMELESS | timeless circadian clock |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TXNL4A | thioredoxin-like 4A |
| USP33 | ubiquitin specific peptidase 33 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF134 | zinc finger protein 134 |
| ZNF227 | zinc finger protein 227 |
| ZNF45 | zinc finger protein 45 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADCY6 | adenylate cyclase 6 |
| ADORA2B | adenosine A2b receptor |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANO10 | anoctamin 10 |
| ARRB1 | arrestin, beta 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| AUP1 | ancient ubiquitous protein 1 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA11 | carbonic anhydrase XI |
| CAPRIN2 | caprin family member 2 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
| CBR1 | carbonyl reductase 1 |
| CCDC15 | coiled-coil domain containing 15 |
| CCDC94 | coiled-coil domain containing 94 |
| CDK20 | cyclin-dependent kinase 20 |
| CLDN15 | claudin 15 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLSPN | claspin |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COL9A2 | collagen, type IX, alpha 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DBR1 | debranching RNA lariats 1 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EDC4 | enhancer of mRNA decapping 4 |
| ENO2 | enolase 2 (gamma, neuronal) |
| FHOD1 | formin homology 2 domain containing 1 |
| FLCN | folliculin |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPR87 | G protein-coupled receptor 87 |
| GRB7 | growth factor receptor-bound protein 7 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| JADE1 | jade family PHD finger 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0894 | KIAA0894 protein |
| KIZ | kizuna centrosomal protein |
| KLF11 | Kruppel-like factor 11 |
| LAMB3 | laminin, beta 3 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LOC257152 | uncharacterized LOC257152 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP1S | microtubule-associated protein 1S |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MYO1E | myosin IE |
| NBEAL2 | neurobeachin-like 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NOL12 | nucleolar protein 12 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PADI1 | peptidyl arginine deiminase, type I |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLA2G3 | phospholipase A2, group III |
| PROCR | protein C receptor, endothelial |
| PSKH1 | protein serine kinase H1 |
| QSER1 | glutamine and serine rich 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB5B | RAB5B, member RAS oncogene family |
| RANGRF | RAN guanine nucleotide release factor |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM42 | RNA binding motif protein 42 |
| SHARPIN | SHANK-associated RH domain interactor |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| TAOK1 | TAO kinase 1 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TLN1 | talin 1 |
| TMEM104 | transmembrane protein 104 |
| TRIM25 | tripartite motif containing 25 |
| TTC26 | tetratricopeptide repeat domain 26 |
| UBQLN4 | ubiquilin 4 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR76 | WD repeat domain 76 |
| ZNF180 | zinc finger protein 180 |
| ZNF211 | zinc finger protein 211 |
| ZNF552 | zinc finger protein 552 |
| ZNF668 | zinc finger protein 668 |
