| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the metrifonate-1797 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACACB | acetyl-CoA carboxylase beta |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AGFG2 | ArfGAP with FG repeats 2 |
| ANKRD12 | ankyrin repeat domain 12 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ARTN | artemin |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATP13A3 | ATPase type 13A3 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C3ORF52 | chromosome 3 open reading frame 52 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CCNT2 | cyclin T2 |
| CDC5L | cell division cycle 5-like |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| DOK5 | docking protein 5 |
| DTNA | dystrobrevin, alpha |
| DUSP9 | dual specificity phosphatase 9 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EML3 | echinoderm microtubule associated protein like 3 |
| ESR1 | estrogen receptor 1 |
| FAM174B | family with sequence similarity 174, member B |
| FANCF | Fanconi anemia, complementation group F |
| FAT4 | FAT atypical cadherin 4 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FNDC3A | fibronectin type III domain containing 3A |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HMOX1 | heme oxygenase 1 |
| HNMT | histamine N-methyltransferase |
| HTATSF1 | HIV-1 Tat specific factor 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL1RAP | interleukin 1 receptor accessory protein |
| INTS6 | integrator complex subunit 6 |
| ITGA6 | integrin, alpha 6 |
| KIAA1549L | KIAA1549-like |
| LIG3 | ligase III, DNA, ATP-dependent |
| LMO7 | LIM domain 7 |
| LOC644450 | uncharacterized LOC644450 |
| LONP2 | lon peptidase 2, peroxisomal |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAGEF1 | melanoma antigen family F1 |
| MATR3 | matrin 3 |
| MBTD1 | mbt domain containing 1 |
| MDFI | MyoD family inhibitor |
| METTL3 | methyltransferase like 3 |
| MT1F | metallothionein 1F |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLK4 | polo-like kinase 4 |
| PTGES | prostaglandin E synthase |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| RAB2A | RAB2A, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RARS | arginyl-tRNA synthetase |
| RFK | riboflavin kinase |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SCARB2 | scavenger receptor class B, member 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SGSM3 | small G protein signaling modulator 3 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| SPHK2 | sphingosine kinase 2 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| TAZ | tafazzin |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM121 | transmembrane protein 121 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNS2 | tensin 2 |
| TREX1 | three prime repair exonuclease 1 |
| TRIM29 | tripartite motif containing 29 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| UBXN7 | UBX domain protein 7 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WWOX | WW domain containing oxidoreductase |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZNF329 | zinc finger protein 329 |
| ZNF408 | zinc finger protein 408 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALPK1 | alpha-kinase 1 |
| ANGEL1 | angel homolog 1 (Drosophila) |
| APH1B | APH1B gamma secretase subunit |
| ARSJ | arylsulfatase family, member J |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNPY3 | canopy FGF signaling regulator 3 |
| CORO1A | coronin, actin binding protein, 1A |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DEAF1 | DEAF1 transcription factor |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNMBP | dynamin binding protein |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EFNA3 | ephrin-A3 |
| ETV4 | ets variant 4 |
| EXOC5 | exocyst complex component 5 |
| FAM155A | family with sequence similarity 155, member A |
| FANCE | Fanconi anemia, complementation group E |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPR1 | G protein-coupled receptor 1 |
| HIST1H4J | histone cluster 1, H4j |
| HLX | H2.0-like homeobox |
| ICK | intestinal cell (MAK-like) kinase |
| IL32 | interleukin 32 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IRF9 | interferon regulatory factor 9 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KPTN | kaptin (actin binding protein) |
| MED9 | mediator complex subunit 9 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYO1D | myosin ID |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| OLFML2A | olfactomedin-like 2A |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| P3H1 | prolyl 3-hydroxylase 1 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLH | polymerase (DNA directed), eta |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTK6 | protein tyrosine kinase 6 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAB4B | RAB4B, member RAS oncogene family |
| RBM42 | RNA binding motif protein 42 |
| RIN1 | Ras and Rab interactor 1 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SPATA2L | spermatogenesis associated 2-like |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAGLN | transgelin |
| TEX40 | testis expressed 40 |
| TH | tyrosine hydroxylase |
| TLN1 | talin 1 |
| TMEM120B | transmembrane protein 120B |
| TMEM132A | transmembrane protein 132A |
| TMEM177 | transmembrane protein 177 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBB2B | tubulin, beta 2B class IIb |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| XAB2 | XPA binding protein 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF276 | zinc finger protein 276 |
| ZNF574 | zinc finger protein 574 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
