| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the metrifonate-1839 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTN2 | actinin, alpha 2 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| APOE | apolipoprotein E |
| APOL2 | apolipoprotein L, 2 |
| ARG1 | arginase 1 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATF6B | activating transcription factor 6 beta |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BGN | biglycan |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CD300C | CD300c molecule |
| CDK10 | cyclin-dependent kinase 10 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CNTLN | centlein, centrosomal protein |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DOK5 | docking protein 5 |
| DUSP1 | dual specificity phosphatase 1 |
| E2F5 | E2F transcription factor 5, p130-binding |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GPSM3 | G-protein signaling modulator 3 |
| HINFP | histone H4 transcription factor |
| HK2 | hexokinase 2 |
| ICAM2 | intercellular adhesion molecule 2 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 |
| IQCK | IQ motif containing K |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| JAG2 | jagged 2 |
| KIAA0753 | KIAA0753 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MIIP | migration and invasion inhibitory protein |
| MINK1 | misshapen-like kinase 1 |
| MPZL1 | myelin protein zero-like 1 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NEB | nebulin |
| NIPAL2 | NIPA-like domain containing 2 |
| NUFIP1 | nuclear fragile X mental retardation protein interacting protein 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHF20L1 | PHD finger protein 20-like 1 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PRMT2 | protein arginine methyltransferase 2 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| RBKS | ribokinase |
| REC8 | REC8 meiotic recombination protein |
| REEP1 | receptor accessory protein 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RUNX1 | runt-related transcription factor 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCLY | selenocysteine lyase |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SERINC5 | serine incorporator 5 |
| SH3BP1 | SH3-domain binding protein 1 |
| SHOX2 | short stature homeobox 2 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMYD2 | SET and MYND domain containing 2 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TGFB1 | transforming growth factor, beta 1 |
| TMEM134 | transmembrane protein 134 |
| TMEM70 | transmembrane protein 70 |
| TMEM80 | transmembrane protein 80 |
| TPD52 | tumor protein D52 |
| TUBA4B | tubulin, alpha 4b |
| TUBB2A | tubulin, beta 2A class IIa |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VEGFA | vascular endothelial growth factor A |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZNF426 | zinc finger protein 426 |
| ZNF467 | zinc finger protein 467 |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| ACYP2 | acylphosphatase 2, muscle type |
| AHCTF1 | AT hook containing transcription factor 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BRD9 | bromodomain containing 9 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C3 | complement component 3 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CBX4 | chromobox homolog 4 |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC88C | coiled-coil domain containing 88C |
| CCDC94 | coiled-coil domain containing 94 |
| CD82 | CD82 molecule |
| CENPB | centromere protein B, 80kDa |
| CEP72 | centrosomal protein 72kDa |
| CEP97 | centrosomal protein 97kDa |
| CHMP1A | charged multivesicular body protein 1A |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DSE | dermatan sulfate epimerase |
| ERCC6L | excision repair cross-complementation group 6-like |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FBRS | fibrosin |
| GPR63 | G protein-coupled receptor 63 |
| GTF2I | general transcription factor IIi |
| HIST1H2BI | histone cluster 1, H2bi |
| HP | haptoglobin |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KIF13B | kinesin family member 13B |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 |
| MCRS1 | microspherule protein 1 |
| MGC12488 | |
| MICA | MHC class I polypeptide-related sequence A |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MON1B | MON1 secretory trafficking family member B |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MTMR6 | myotubularin related protein 6 |
| NARFL | nuclear prelamin A recognition factor-like |
| NKRF | NFKB repressing factor |
| NLRX1 | NLR family member X1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PAK1IP1 | PAK1 interacting protein 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PHC2 | polyhomeotic homolog 2 (Drosophila) |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PROSER1 | proline and serine rich 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB17 | RAB17, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RNF121 | ring finger protein 121 |
| RNF122 | ring finger protein 122 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RSF1 | remodeling and spacing factor 1 |
| SECISBP2 | SECIS binding protein 2 |
| SEPW1 | selenoprotein W, 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SHPK | sedoheptulokinase |
| SIRT6 | sirtuin 6 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TEC | tec protein tyrosine kinase |
| THOP1 | thimet oligopeptidase 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM183A | transmembrane protein 183A |
| TMEM242 | transmembrane protein 242 |
| TRAF1 | TNF receptor-associated factor 1 |
| TRIM16 | tripartite motif containing 16 |
| TXLNG | taxilin gamma |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| USP19 | ubiquitin specific peptidase 19 |
| XAB2 | XPA binding protein 2 |
| XPO4 | exportin 4 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF10 | zinc finger protein 10 |
| ZNF197 | zinc finger protein 197 |
| ZNF592 | zinc finger protein 592 |
| ZNF665 | zinc finger protein 665 |
| ZNF701 | zinc finger protein 701 |
