| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the metrifonate-5989 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AFF4 | AF4/FMR2 family, member 4 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CD300C | CD300c molecule |
| CD52 | CD52 molecule |
| CD86 | CD86 molecule |
| CDHR2 | cadherin-related family member 2 |
| CFHR4 | complement factor H-related 4 |
| CGA | glycoprotein hormones, alpha polypeptide |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CUL3 | cullin 3 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| EMC3 | ER membrane protein complex subunit 3 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| FGB | fibrinogen beta chain |
| FGF18 | fibroblast growth factor 18 |
| FLJ11292 | |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GFER | growth factor, augmenter of liver regeneration |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GK | glycerol kinase |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRB10 | growth factor receptor-bound protein 10 |
| HCFC1 | host cell factor C1 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IAPP | islet amyloid polypeptide |
| IFI35 | interferon-induced protein 35 |
| IL16 | interleukin 16 |
| IL1R2 | interleukin 1 receptor, type II |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LAMA2 | laminin, alpha 2 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MCPH1 | microcephalin 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMP3 | matrix metallopeptidase 3 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MUC4 | mucin 4, cell surface associated |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYO9B | myosin IXB |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NKX2-8 | NK2 homeobox 8 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NRF1 | nuclear respiratory factor 1 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PAX9 | paired box 9 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAB11B | RAB11B, member RAS oncogene family |
| RASAL2 | RAS protein activator like 2 |
| RNF19B | ring finger protein 19B |
| RNF39 | ring finger protein 39 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SH3BP2 | SH3-domain binding protein 2 |
| SIRT5 | sirtuin 5 |
| SLC35E2 | solute carrier family 35, member E2 |
| SP100 | SP100 nuclear antigen |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TLR8 | toll-like receptor 8 |
| TMEM259 | transmembrane protein 259 |
| TPMT | thiopurine S-methyltransferase |
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) |
| UBQLN4 | ubiquilin 4 |
| ZNF259P1 | zinc finger protein 259 pseudogene 1 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ANO10 | anoctamin 10 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL9 | B-cell CLL/lymphoma 9 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCDC85C | coiled-coil domain containing 85C |
| CHKB | choline kinase beta |
| CHPF | chondroitin polymerizing factor |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| DEAF1 | DEAF1 transcription factor |
| DENND4A | DENN/MADD domain containing 4A |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFHD2 | EF-hand domain family, member D2 |
| EFNA3 | ephrin-A3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERCC4 | excision repair cross-complementation group 4 |
| FADS2 | fatty acid desaturase 2 |
| FZD2 | frizzled class receptor 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLI3 | GLI family zinc finger 3 |
| GMPR | guanosine monophosphate reductase |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HPN | hepsin |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HYI | hydroxypyruvate isomerase (putative) |
| IPP | intracisternal A particle-promoted polypeptide |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINS | lines homolog (Drosophila) |
| LOC730101 | uncharacterized LOC730101 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MVP | major vault protein |
| NBEAL2 | neurobeachin-like 2 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| OLFML3 | olfactomedin-like 3 |
| PDE12 | phosphodiesterase 12 |
| PDE8B | phosphodiesterase 8B |
| PGBD5 | piggyBac transposable element derived 5 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PROL1 | proline rich, lacrimal 1 |
| PRR14L | proline rich 14-like |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB3D | RAB3D, member RAS oncogene family |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| S100A4 | S100 calcium binding protein A4 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCAI | suppressor of cancer cell invasion |
| SH2D4A | SH2 domain containing 4A |
| SIK1 | salt-inducible kinase 1 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SPRYD7 | SPRY domain containing 7 |
| TDRD1 | tudor domain containing 1 |
| THBS3 | thrombospondin 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM121 | transmembrane protein 121 |
| TMEM212 | transmembrane protein 212 |
| TMEM254 | transmembrane protein 254 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| WFDC2 | WAP four-disulfide core domain 2 |
| XK | X-linked Kx blood group |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF428 | zinc finger protein 428 |
| ZNF430 | zinc finger protein 430 |
| ZNF574 | zinc finger protein 574 |
| ZNF652 | zinc finger protein 652 |
