| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the metrifonate-7287 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD82 | CD82 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CNTNAP2 | contactin associated protein-like 2 |
| COL3A1 | collagen, type III, alpha 1 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CTAGE5 | CTAGE family, member 5 |
| CUL7 | cullin 7 |
| DUSP8 | dual specificity phosphatase 8 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM65A | family with sequence similarity 65, member A |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FGF5 | fibroblast growth factor 5 |
| FLJ11292 | |
| FN1 | fibronectin 1 |
| FOXJ3 | forkhead box J3 |
| GLE1 | GLE1 RNA export mediator |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HOXA4 | homeobox A4 |
| HOXC5 | homeobox C5 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IL4R | interleukin 4 receptor |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KHK | ketohexokinase (fructokinase) |
| KLHL22 | kelch-like family member 22 |
| LIG3 | ligase III, DNA, ATP-dependent |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MARS | methionyl-tRNA synthetase |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MECOM | MDS1 and EVI1 complex locus |
| MED18 | mediator complex subunit 18 |
| MFAP3 | microfibrillar-associated protein 3 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MIIP | migration and invasion inhibitory protein |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MRC2 | mannose receptor, C type 2 |
| MSX2 | msh homeobox 2 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCOA2 | nuclear receptor coactivator 2 |
| NINJ1 | ninjurin 1 |
| NPEPL1 | aminopeptidase-like 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PAX2 | paired box 2 |
| PCM1 | pericentriolar material 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PMCH | pro-melanin-concentrating hormone |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB26 | RAB26, member RAS oncogene family |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RUNX1 | runt-related transcription factor 1 |
| SCG5 | secretogranin V |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SPAST | spastin |
| SRCAP | Snf2-related CREBBP activator protein |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| STX3 | syntaxin 3 |
| TBC1D22A | TBC1 domain family, member 22A |
| TCF12 | transcription factor 12 |
| TIMELESS | timeless circadian clock |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM180 | transmembrane protein 180 |
| TMEM259 | transmembrane protein 259 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| UNC45A | unc-45 homolog A (C. elegans) |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| WDR4 | WD repeat domain 4 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF205 | zinc finger protein 205 |
| ZNF222 | zinc finger protein 222 |
| ZNF44 | zinc finger protein 44 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BAG4 | BCL2-associated athanogene 4 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| CCDC47 | coiled-coil domain containing 47 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CENPT | centromere protein T |
| CHMP6 | charged multivesicular body protein 6 |
| CHMP7 | charged multivesicular body protein 7 |
| CLDN14 | claudin 14 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COPG1 | coatomer protein complex, subunit gamma 1 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DLL3 | delta-like 3 (Drosophila) |
| ECI1 | enoyl-CoA delta isomerase 1 |
| EPN3 | epsin 3 |
| ETNK2 | ethanolamine kinase 2 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM102A | family with sequence similarity 102, member A |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FKBPL | FK506 binding protein like |
| FOXC1 | forkhead box C1 |
| FPGS | folylpolyglutamate synthase |
| H1F0 | H1 histone family, member 0 |
| HIRA | histone cell cycle regulator |
| HOXC10 | homeobox C10 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| IGFLR1 | IGF-like family receptor 1 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| IREB2 | iron-responsive element binding protein 2 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KDELC1 | KDEL (Lys-Asp-Glu-Leu) containing 1 |
| KIFC1 | kinesin family member C1 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LOC100127972 | uncharacterized LOC100127972 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MANBA | mannosidase, beta A, lysosomal |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MCM9 | minichromosome maintenance complex component 9 |
| MCMBP | minichromosome maintenance complex binding protein |
| MTRF1 | mitochondrial translational release factor 1 |
| NABP2 | nucleic acid binding protein 2 |
| NARFL | nuclear prelamin A recognition factor-like |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| OLFML2A | olfactomedin-like 2A |
| OSMR | oncostatin M receptor |
| OTUD3 | OTU deubiquitinase 3 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PEG3 | paternally expressed 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLA2G15 | phospholipase A2, group XV |
| PLCD1 | phospholipase C, delta 1 |
| POLM | polymerase (DNA directed), mu |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| REEP4 | receptor accessory protein 4 |
| RNF170 | ring finger protein 170 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RWDD3 | RWD domain containing 3 |
| SCAI | suppressor of cancer cell invasion |
| SCARA3 | scavenger receptor class A, member 3 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SNX16 | sorting nexin 16 |
| SPATA7 | spermatogenesis associated 7 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAR | steroidogenic acute regulatory protein |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM209 | transmembrane protein 209 |
| TPCN1 | two pore segment channel 1 |
| TRIM26 | tripartite motif containing 26 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSKU | tsukushi, small leucine rich proteoglycan |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF33B | zinc finger protein 33B |
| ZNF580 | zinc finger protein 580 |
| ZNF767P | zinc finger family member 767, pseudogene |
