metrizamide-1318 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the metrizamide-1318 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX3 acyl-CoA oxidase 3, pristanoyl
ALAD aminolevulinate dehydratase
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
AQP1 aquaporin 1 (Colton blood group)
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BAG4 BCL2-associated athanogene 4
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BTG2 BTG family, member 2
C22ORF46 chromosome 22 open reading frame 46
C6ORF62 chromosome 6 open reading frame 62
CAPN2 calpain 2, (m/II) large subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBR1 carbonyl reductase 1
CCNG2 cyclin G2
CDV3 CDV3 homolog (mouse)
CELF1 CUGBP, Elav-like family member 1
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CEP290 centrosomal protein 290kDa
CHML choroideremia-like (Rab escort protein 2)
CLIC4 chloride intracellular channel 4
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DBT dihydrolipoamide branched chain transacylase E2
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP3 dual specificity phosphatase 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FCF1 FCF1 rRNA-processing protein
GALC galactosylceramidase
GTF2I general transcription factor IIi
HCRP1 hepatocellular carcinoma-related HCRP1
HIPK3 homeodomain interacting protein kinase 3
HIST1H3H histone cluster 1, H3h
HSF1 heat shock transcription factor 1
HSF2 heat shock transcription factor 2
HYAL2 hyaluronoglucosaminidase 2
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INCENP inner centromere protein antigens 135/155kDa
INO80B INO80 complex subunit B
IPO8 importin 8
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
IZUMO4 IZUMO family member 4
LPAR1 lysophosphatidic acid receptor 1
LYST lysosomal trafficking regulator
MAP4 microtubule-associated protein 4
MAPK14 mitogen-activated protein kinase 14
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED28 mediator complex subunit 28
MEFV Mediterranean fever
MFAP3 microfibrillar-associated protein 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTFR1 mitochondrial fission regulator 1
NADK NAD kinase
NCOA3 nuclear receptor coactivator 3
NCS1 neuronal calcium sensor 1
NFYA nuclear transcription factor Y, alpha
NMT1 N-myristoyltransferase 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PENK proenkephalin
PEX10 peroxisomal biogenesis factor 10
PICALM phosphatidylinositol binding clathrin assembly protein
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLK4 polo-like kinase 4
PNRC1 proline-rich nuclear receptor coactivator 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB6A RAB6A, member RAS oncogene family
RASA3 RAS p21 protein activator 3
RCAN1 regulator of calcineurin 1
RNF141 ring finger protein 141
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPAP2 RNA polymerase II associated protein 2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SCAMP1 secretory carrier membrane protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC2 syndecan 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SOD2 superoxide dismutase 2, mitochondrial
SOS2 son of sevenless homolog 2 (Drosophila)
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STAT1 signal transducer and activator of transcription 1, 91kDa
STX16 syntaxin 16
SVIL supervillin
SYNJ1 synaptojanin 1
TLR8 toll-like receptor 8
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TPR translocated promoter region, nuclear basket protein
TRIM36 tripartite motif containing 36
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
XYLT2 xylosyltransferase II
YTHDC1 YTH domain containing 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
AES amino-terminal enhancer of split
ANKRD40 ankyrin repeat domain 40
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOLD1 apolipoprotein L domain containing 1
ARHGAP4 Rho GTPase activating protein 4
ARID5A AT rich interactive domain 5A (MRF1-like)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG4A autophagy related 4A, cysteine peptidase
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BAHD1 bromo adjacent homology domain containing 1
C7ORF43 chromosome 7 open reading frame 43
C8ORF44 chromosome 8 open reading frame 44
C9ORF114 chromosome 9 open reading frame 114
CAMTA2 calmodulin binding transcription activator 2
CCDC25 coiled-coil domain containing 25
CD1D CD1d molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CHST10 carbohydrate sulfotransferase 10
CIDEB cell death-inducing DFFA-like effector b
CISH cytokine inducible SH2-containing protein
COL9A2 collagen, type IX, alpha 2
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CTDNEP1 CTD nuclear envelope phosphatase 1
CUL9 cullin 9
CXORF56 chromosome X open reading frame 56
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHRS9 dehydrogenase/reductase (SDR family) member 9
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DNAL4 dynein, axonemal, light chain 4
DUSP2 dual specificity phosphatase 2
DVL1 dishevelled segment polarity protein 1
DYSF dysferlin
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EPHB6 EPH receptor B6
EXD2 exonuclease 3'-5' domain containing 2
FADS2 fatty acid desaturase 2
FAM222B family with sequence similarity 222, member B
FAM50B family with sequence similarity 50, member B
FBRS fibrosin
FOSL1 FOS-like antigen 1
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
HDAC5 histone deacetylase 5
HINFP histone H4 transcription factor
HP haptoglobin
HPS6 Hermansky-Pudlak syndrome 6
HYAL3 hyaluronoglucosaminidase 3
IGSF6 immunoglobulin superfamily, member 6
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INF2 inverted formin, FH2 and WH2 domain containing
KIAA0753 KIAA0753
LAMP5 lysosomal-associated membrane protein family, member 5
LOC157562 uncharacterized LOC157562
MAST3 microtubule associated serine/threonine kinase 3
MED15 mediator complex subunit 15
MFSD12 major facilitator superfamily domain containing 12
MID1IP1 MID1 interacting protein 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MMP2 matrix metallopeptidase 2
NKRF NFKB repressing factor
NSD1 nuclear receptor binding SET domain protein 1
NTSR1 neurotensin receptor 1 (high affinity)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
POLH polymerase (DNA directed), eta
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
RNF122 ring finger protein 122
RNF167 ring finger protein 167
RPAP1 RNA polymerase II associated protein 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SAMD9 sterile alpha motif domain containing 9
SAP30L SAP30-like
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIDT1 SID1 transmembrane family, member 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLITRK5 SLIT and NTRK-like family, member 5
SNHG20 small nucleolar RNA host gene 20
SPAG4 sperm associated antigen 4
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TBCCD1 TBCC domain containing 1
THEM6 thioesterase superfamily member 6
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM110 transmembrane protein 110
TMEM184B transmembrane protein 184B
TMEM187 transmembrane protein 187
TNNT1 troponin T type 1 (skeletal, slow)
TRIM26 tripartite motif containing 26
TSPAN32 tetraspanin 32
UBQLN4 ubiquilin 4
ULK1 unc-51 like autophagy activating kinase 1
WWC3 WWC family member 3
YEATS4 YEATS domain containing 4
ZMAT5 zinc finger, matrin-type 5
ZNF34 zinc finger protein 34
ZNF571 zinc finger protein 571
ZNF767P zinc finger family member 767, pseudogene