metrizamide-3255 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the metrizamide-3255 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APOM apolipoprotein M
ARHGAP17 Rho GTPase activating protein 17
ASPH aspartate beta-hydroxylase
ATAT1 alpha tubulin acetyltransferase 1
ATN1 atrophin 1
BTD biotinidase
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF54 chromosome 1 open reading frame 54
C22ORF46 chromosome 22 open reading frame 46
C5ORF45 chromosome 5 open reading frame 45
CDC25A cell division cycle 25A
CLEC4E C-type lectin domain family 4, member E
CLGN calmegin
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CPOX coproporphyrinogen oxidase
CTNS cystinosin, lysosomal cystine transporter
CTSF cathepsin F
DAAM2 dishevelled associated activator of morphogenesis 2
DGCR8 DGCR8 microprocessor complex subunit
DTNA dystrobrevin, alpha
ELOVL2 ELOVL fatty acid elongase 2
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL2 F-box and leucine-rich repeat protein 2
FBXO11 F-box protein 11
FCF1 FCF1 rRNA-processing protein
FGFR1 fibroblast growth factor receptor 1
FN1 fibronectin 1
FRY furry homolog (Drosophila)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GOLIM4 golgi integral membrane protein 4
GPER1 G protein-coupled estrogen receptor 1
GYG2 glycogenin 2
H1F0 H1 histone family, member 0
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCTD17 potassium channel tetramerization domain containing 17
KCTD2 potassium channel tetramerization domain containing 2
KITLG KIT ligand
KLHDC8A kelch domain containing 8A
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMO4 LIM domain only 4
LOXL2 lysyl oxidase-like 2
MCOLN3 mucolipin 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
METAP2 methionyl aminopeptidase 2
MTA2 metastasis associated 1 family, member 2
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOF myoferlin
N4BP2L2 NEDD4 binding protein 2-like 2
NCAPH2 non-SMC condensin II complex, subunit H2
NDRG2 NDRG family member 2
NFIB nuclear factor I/B
NME5 NME/NM23 family member 5
NPM3 nucleophosmin/nucleoplasmin 3
NUMA1 nuclear mitotic apparatus protein 1
NUP214 nucleoporin 214kDa
OGFRL1 opioid growth factor receptor-like 1
PAIP2B poly(A) binding protein interacting protein 2B
PAPOLA poly(A) polymerase alpha
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PQLC3 PQ loop repeat containing 3
PYHIN1 pyrin and HIN domain family, member 1
RAD54B RAD54 homolog B (S. cerevisiae)
RFPL3 ret finger protein-like 3
RHEB Ras homolog enriched in brain
RIMS2 regulating synaptic membrane exocytosis 2
S100A13 S100 calcium binding protein A13
SAFB scaffold attachment factor B
SDS serine dehydratase
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIK3 SIK family kinase 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35E2 solute carrier family 35, member E2
SNTA1 syntrophin, alpha 1
SNW1 SNW domain containing 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STRN3 striatin, calmodulin binding protein 3
SUGP1 SURP and G patch domain containing 1
TAGLN2 transgelin 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TGFB2 transforming growth factor, beta 2
THAP3 THAP domain containing, apoptosis associated protein 3
TYMS thymidylate synthetase
UPK3B uroplakin 3B
USP9Y ubiquitin specific peptidase 9, Y-linked
WNT16 wingless-type MMTV integration site family, member 16
ZNF318 zinc finger protein 318
ZNF516 zinc finger protein 516
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ADAP2 ArfGAP with dual PH domains 2
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ASB9 ankyrin repeat and SOCS box containing 9
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AXIN1 axin 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C4ORF29 chromosome 4 open reading frame 29
C9ORF9 chromosome 9 open reading frame 9
CGA glycoprotein hormones, alpha polypeptide
CIC capicua transcriptional repressor
CLSPN claspin
COL9A2 collagen, type IX, alpha 2
CRY2 cryptochrome circadian clock 2
CXORF56 chromosome X open reading frame 56
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
EXO5 exonuclease 5
FAAH fatty acid amide hydrolase
FAM184A family with sequence similarity 184, member A
FAM188A family with sequence similarity 188, member A
FBRS fibrosin
FBXW12 F-box and WD repeat domain containing 12
FCHO1 FCH domain only 1
FHOD1 formin homology 2 domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPATCH3 G patch domain containing 3
GSTA4 glutathione S-transferase alpha 4
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BI histone cluster 1, H2bi
HIST1H2BO histone cluster 1, H2bo
HIST1H4F histone cluster 1, H4f
IL17RA interleukin 17 receptor A
IRAK4 interleukin-1 receptor-associated kinase 4
JMJD4 jumonji domain containing 4
KIAA0319L KIAA0319-like
KLF2 Kruppel-like factor 2
KLK5 kallikrein-related peptidase 5
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTR1 leucine-zipper-like transcription regulator 1
MBTD1 mbt domain containing 1
MITF microphthalmia-associated transcription factor
NRGN neurogranin (protein kinase C substrate, RC3)
OTUD3 OTU deubiquitinase 3
PCDHA9 protocadherin alpha 9
PGBD5 piggyBac transposable element derived 5
PGM1 phosphoglucomutase 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POM121 POM121 transmembrane nucleoporin
PRAMEF11 PRAME family member 11
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB17 RAB17, member RAS oncogene family
RFWD3 ring finger and WD repeat domain 3
RHBDD3 rhomboid domain containing 3
RNF122 ring finger protein 122
RNF2 ring finger protein 2
RPL23AP32 ribosomal protein L23a pseudogene 32
SCGB2A2 secretoglobin, family 2A, member 2
SH3BGR SH3 domain binding glutamate-rich protein
SIK1 salt-inducible kinase 1
SIX1 SIX homeobox 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMIM14 small integral membrane protein 14
SNAI2 snail family zinc finger 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM6SF1 transmembrane 6 superfamily member 1
TM7SF3 transmembrane 7 superfamily member 3
TMEM121 transmembrane protein 121
TNS2 tensin 2
TPCN1 two pore segment channel 1
TRIM16 tripartite motif containing 16
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
USP36 ubiquitin specific peptidase 36
USP6NL USP6 N-terminal like
VASH2 vasohibin 2
VWA1 von Willebrand factor A domain containing 1
WDR25 WD repeat domain 25
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZMAT5 zinc finger, matrin-type 5
ZNF160 zinc finger protein 160
ZNF324 zinc finger protein 324
ZNF652 zinc finger protein 652
ZNF778 zinc finger protein 778