metrizamide-4075 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the metrizamide-4075 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACOX3 acyl-CoA oxidase 3, pristanoyl
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADGRB2 adhesion G protein-coupled receptor B2
ALOX12 arachidonate 12-lipoxygenase
AMPH amphiphysin
AVIL advillin
BIRC7 baculoviral IAP repeat containing 7
C8ORF4 chromosome 8 open reading frame 4
CADM1 cell adhesion molecule 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD22 CD22 molecule
CD300A CD300a molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CEP295 centrosomal protein 295kDa
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLCA2 chloride channel accessory 2
CLEC1A C-type lectin domain family 1, member A
CLTA clathrin, light chain A
COL17A1 collagen, type XVII, alpha 1
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CYTH1 cytohesin 1
DDN dendrin
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DRD2 dopamine receptor D2
EDN3 endothelin 3
ELK1 ELK1, member of ETS oncogene family
EMC3 ER membrane protein complex subunit 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP3 fatty acid binding protein 3, muscle and heart
FAM189A2 family with sequence similarity 189, member A2
GAS7 growth arrest-specific 7
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GRIK1 glutamate receptor, ionotropic, kainate 1
HAO2 hydroxyacid oxidase 2 (long chain)
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2AL histone cluster 1, H2al
HPSE2 heparanase 2 (inactive)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IGH immunoglobulin heavy locus
IL2 interleukin 2
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
LEFTY2 left-right determination factor 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC100287387 uncharacterized LOC100287387
MAP2K7 mitogen-activated protein kinase kinase 7
MBL2 mannose-binding lectin (protein C) 2, soluble
MYCNOS MYCN opposite strand
MYH15 myosin, heavy chain 15
OLFM1 olfactomedin 1
OMD osteomodulin
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PCDH11Y protocadherin 11 Y-linked
PCDH7 protocadherin 7
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDE11A phosphodiesterase 11A
PDGFB platelet-derived growth factor beta polypeptide
PDIA2 protein disulfide isomerase family A, member 2
PHOX2A paired-like homeobox 2a
PKNOX1 PBX/knotted 1 homeobox 1
POLL polymerase (DNA directed), lambda
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRB3 proline-rich protein BstNI subfamily 3
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RIMS2 regulating synaptic membrane exocytosis 2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAFB scaffold attachment factor B
SAGE1 sarcoma antigen 1
SAMD4A sterile alpha motif domain containing 4A
SASH3 SAM and SH3 domain containing 3
SBSPON somatomedin B and thrombospondin, type 1 domain containing
SCN10A sodium channel, voltage gated, type X alpha subunit
SERHL2 serine hydrolase-like 2
SH3GL3 SH3-domain GRB2-like 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPRED2 sprouty-related, EVH1 domain containing 2
SRSF7 serine/arginine-rich splicing factor 7
ST7L suppression of tumorigenicity 7 like
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TBX10 T-box 10
TESPA1 thymocyte expressed, positive selection associated 1
TFEB transcription factor EB
TP53TG5 TP53 target 5
TPM2 tropomyosin 2 (beta)
TSHR thyroid stimulating hormone receptor
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF484 zinc finger protein 484
ZNF609 zinc finger protein 609
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARR3 arrestin 3, retinal (X-arrestin)
ASTN1 astrotactin 1
ATG10 autophagy related 10
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAGE B melanoma antigen
BFSP1 beaded filament structural protein 1, filensin
C16ORF45 chromosome 16 open reading frame 45
C19ORF40 chromosome 19 open reading frame 40
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAMKMT calmodulin-lysine N-methyltransferase
CD79B CD79b molecule, immunoglobulin-associated beta
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CLIC3 chloride intracellular channel 3
CNTFR ciliary neurotrophic factor receptor
CPEB1 cytoplasmic polyadenylation element binding protein 1
CSRNP3 cysteine-serine-rich nuclear protein 3
CXORF21 chromosome X open reading frame 21
DBF4B DBF4 zinc finger B
DNAH17 dynein, axonemal, heavy chain 17
EDN1 endothelin 1
EXO5 exonuclease 5
FAM169A family with sequence similarity 169, member A
FBXO31 F-box protein 31
FGL1 fibrinogen-like 1
GRTP1 growth hormone regulated TBC protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H4C histone cluster 1, H4c
HOOK1 hook microtubule-tethering protein 1
HOXC8 homeobox C8
INO80D INO80 complex subunit D
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT31 keratin 31, type I
LIMS2 LIM and senescent cell antigen-like domains 2
LOC157562 uncharacterized LOC157562
LSR lipolysis stimulated lipoprotein receptor
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAGEF1 melanoma antigen family F1
MAL mal, T-cell differentiation protein
MAPK12 mitogen-activated protein kinase 12
MDFI MyoD family inhibitor
MED31 mediator complex subunit 31
MIS18BP1 MIS18 binding protein 1
MMP9 matrix metallopeptidase 9
MTA2 metastasis associated 1 family, member 2
MTERF4 mitochondrial transcription termination factor 4
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOL10 nucleolar protein 10
NOTCH1 notch 1
NXPH4 neurexophilin 4
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PALMD palmdelphin
PAQR6 progestin and adipoQ receptor family member VI
PBOV1 prostate and breast cancer overexpressed 1
PRF1 perforin 1 (pore forming protein)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAPSN receptor-associated protein of the synapse
RASAL2 RAS protein activator like 2
RPL10L ribosomal protein L10-like
RPL13P5 ribosomal protein L13 pseudogene 5
SETD1A SET domain containing 1A
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SND1-IT1 SND1 intronic transcript 1
SPRYD7 SPRY domain containing 7
SPTBN2 spectrin, beta, non-erythrocytic 2
TCEAL2 transcription elongation factor A (SII)-like 2
TENM4 teneurin transmembrane protein 4
TEX40 testis expressed 40
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRAF2 TNF receptor-associated factor 2
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
WDR18 WD repeat domain 18
ZNF268 zinc finger protein 268
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446
ZNF549 zinc finger protein 549
ZNF668 zinc finger protein 668
ZNF747 zinc finger protein 747
ZNF770 zinc finger protein 770