| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the metronidazole-1503 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| APP | amyloid beta (A4) precursor protein |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMC4 | armadillo repeat containing 4 |
| BAX | BCL2-associated X protein |
| BIN1 | bridging integrator 1 |
| C2CD2L | C2CD2-like |
| CALCR | calcitonin receptor |
| CARD14 | caspase recruitment domain family, member 14 |
| CCNO | cyclin O |
| CD34 | CD34 molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CES3 | carboxylesterase 3 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| COL14A1 | collagen, type XIV, alpha 1 |
| CORO7 | coronin 7 |
| CRLF1 | cytokine receptor-like factor 1 |
| DESI2 | desumoylating isopeptidase 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOCK5 | dedicator of cytokinesis 5 |
| ECE1 | endothelin converting enzyme 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM134B | family with sequence similarity 134, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO2 | F-box protein 2 |
| FSCN1 | fascin actin-bundling protein 1 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 |
| HOXC10 | homeobox C10 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| IL1B | interleukin 1, beta |
| ING4 | inhibitor of growth family, member 4 |
| IQCG | IQ motif containing G |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LOXL3 | lysyl oxidase-like 3 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LRRC23 | leucine rich repeat containing 23 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MBD1 | methyl-CpG binding domain protein 1 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| METTL16 | methyltransferase like 16 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MST1 | macrophage stimulating 1 |
| NFS1 | NFS1 cysteine desulfurase |
| NGLY1 | N-glycanase 1 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| PCM1 | pericentriolar material 1 |
| PDCD6 | programmed cell death 6 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PORCN | porcupine homolog (Drosophila) |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTCH1 | patched 1 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAMP2 | receptor (G protein-coupled) activity modifying protein 2 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RBM42 | RNA binding motif protein 42 |
| RPS14 | ribosomal protein S14 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| STK38L | serine/threonine kinase 38 like |
| STS | steroid sulfatase (microsomal), isozyme S |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TFEB | transcription factor EB |
| TMOD1 | tropomodulin 1 |
| TOP3A | topoisomerase (DNA) III alpha |
| TRBC1 | T cell receptor beta constant 1 |
| TRD | T cell receptor delta locus |
| TRIM14 | tripartite motif containing 14 |
| TTC38 | tetratricopeptide repeat domain 38 |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZNF134 | zinc finger protein 134 |
| ZNF44 | zinc finger protein 44 |
| ZNF484 | zinc finger protein 484 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ANKRD36 | ankyrin repeat domain 36 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARRB1 | arrestin, beta 1 |
| ARRB2 | arrestin, beta 2 |
| ARSB | arylsulfatase B |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CBX4 | chromobox homolog 4 |
| CCDC69 | coiled-coil domain containing 69 |
| CCDC9 | coiled-coil domain containing 9 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CENPJ | centromere protein J |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CSF1R | colony stimulating factor 1 receptor |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP2 | dual specificity phosphatase 2 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| FGL1 | fibrinogen-like 1 |
| FKBP5 | FK506 binding protein 5 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIRA | histone cell cycle regulator |
| HMHA1 | histocompatibility (minor) HA-1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KLHL25 | kelch-like family member 25 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MCC | mutated in colorectal cancers |
| MEFV | Mediterranean fever |
| METTL2B | methyltransferase like 2B |
| MFAP2 | microfibrillar-associated protein 2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MVP | major vault protein |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PCDHA9 | protocadherin alpha 9 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PRKCE | protein kinase C, epsilon |
| PRMT7 | protein arginine methyltransferase 7 |
| PRPH | peripherin |
| PRR4 | proline rich 4 (lacrimal) |
| PTGES | prostaglandin E synthase |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB3D | RAB3D, member RAS oncogene family |
| RHBDD3 | rhomboid domain containing 3 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF2 | ring finger protein 2 |
| RNF31 | ring finger protein 31 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPAG4 | sperm associated antigen 4 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STBD1 | starch binding domain 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| TGFB3 | transforming growth factor, beta 3 |
| TMEM53 | transmembrane protein 53 |
| TMEM57 | transmembrane protein 57 |
| TUBA3C | tubulin, alpha 3c |
| UBQLN4 | ubiquilin 4 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VPS9D1 | VPS9 domain containing 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZNF250 | zinc finger protein 250 |
| ZNF423 | zinc finger protein 423 |
| ZNF442 | zinc finger protein 442 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
