| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the metronidazole-1921 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ACTL6A | actin-like 6A |
| ADCY7 | adenylate cyclase 7 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| ADK | adenosine kinase |
| AHCTF1 | AT hook containing transcription factor 1 |
| ALAD | aminolevulinate dehydratase |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ANGPT1 | angiopoietin 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| ATN1 | atrophin 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BCLAF1 | BCL2-associated transcription factor 1 |
| BMP2K | BMP2 inducible kinase |
| BTN1A1 | butyrophilin, subfamily 1, member A1 |
| CALB2 | calbindin 2 |
| CD300A | CD300a molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEP57 | centrosomal protein 57kDa |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 |
| CYTH4 | cytohesin 4 |
| DLX2 | distal-less homeobox 2 |
| DUSP10 | dual specificity phosphatase 10 |
| EIF4E | eukaryotic translation initiation factor 4E |
| EIF5B | eukaryotic translation initiation factor 5B |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLJ42627 | uncharacterized LOC645644 |
| FOXC1 | forkhead box C1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GBX2 | gastrulation brain homeobox 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNL1 | guanine nucleotide binding protein-like 1 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HLA-B | major histocompatibility complex, class I, B |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IL2RG | interleukin 2 receptor, gamma |
| IL9R | interleukin 9 receptor |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KIAA0195 | KIAA0195 |
| KIF25 | kinesin family member 25 |
| KLHL23 | kelch-like family member 23 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) |
| LIN7C | lin-7 homolog C (C. elegans) |
| MAPK7 | mitogen-activated protein kinase 7 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MR1 | major histocompatibility complex, class I-related |
| MRC2 | mannose receptor, C type 2 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MVP | major vault protein |
| NHLRC2 | NHL repeat containing 2 |
| OR2S2 | olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PCM1 | pericentriolar material 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLLP | plasmolipin |
| PNMT | phenylethanolamine N-methyltransferase |
| POFUT2 | protein O-fucosyltransferase 2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTGES | prostaglandin E synthase |
| PTH1R | parathyroid hormone 1 receptor |
| RANBP3 | RAN binding protein 3 |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RNF39 | ring finger protein 39 |
| RPL31 | ribosomal protein L31 |
| RWDD3 | RWD domain containing 3 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) |
| SPN | sialophorin |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| THBS3 | thrombospondin 3 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TMEM206 | transmembrane protein 206 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TSHZ2 | teashirt zinc finger homeobox 2 |
| UBA3 | ubiquitin-like modifier activating enzyme 3 |
| UBQLN4 | ubiquilin 4 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACTR10 | actin-related protein 10 homolog (S. cerevisiae) |
| AKTIP | AKT interacting protein |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase |
| APIP | APAF1 interacting protein |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa |
| ATP5I | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E |
| BCL10 | B-cell CLL/lymphoma 10 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C1D | C1D nuclear receptor corepressor |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C3ORF14 | chromosome 3 open reading frame 14 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CDC23 | cell division cycle 23 |
| CDC73 | cell division cycle 73 |
| CDK8 | cyclin-dependent kinase 8 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 |
| COMMD8 | COMM domain containing 8 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component |
| CYB561D2 | cytochrome b561 family, member D2 |
| EHD4 | EH-domain containing 4 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| FAM35A | family with sequence similarity 35, member A |
| FAM46A | family with sequence similarity 46, member A |
| FAR2 | fatty acyl CoA reductase 2 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FXN | frataxin |
| GAB2 | GRB2-associated binding protein 2 |
| GABARAP | GABA(A) receptor-associated protein |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 |
| GHR | growth hormone receptor |
| GLTP | glycolipid transfer protein |
| GPN3 | GPN-loop GTPase 3 |
| GRHL2 | grainyhead-like 2 (Drosophila) |
| H1F0 | H1 histone family, member 0 |
| H1FX | H1 histone family, member X |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
| HIST1H2BC | histone cluster 1, H2bc |
| HMGB2 | high mobility group box 2 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IRF6 | interferon regulatory factor 6 |
| IRS1 | insulin receptor substrate 1 |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KLHDC2 | kelch domain containing 2 |
| LRRC16A | leucine rich repeat containing 16A |
| LTN1 | listerin E3 ubiquitin protein ligase 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MFF | mitochondrial fission factor |
| MICU2 | mitochondrial calcium uptake 2 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MREG | melanoregulin |
| MRFAP1L1 | Morf4 family associated protein 1-like 1 |
| MRPL33 | mitochondrial ribosomal protein L33 |
| MRPS33 | mitochondrial ribosomal protein S33 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NAE1 | NEDD8 activating enzyme E1 subunit 1 |
| NDC1 | NDC1 transmembrane nucleoporin |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NINJ1 | ninjurin 1 |
| NIPA2 | non imprinted in Prader-Willi/Angelman syndrome 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUPL1 | nucleoporin like 1 |
| NVL | nuclear VCP-like |
| ORC2 | origin recognition complex, subunit 2 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLS1 | plastin 1 |
| POLR2G | polymerase (RNA) II (DNA directed) polypeptide G |
| PRKRIR | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 |
| RAB5B | RAB5B, member RAS oncogene family |
| RANBP6 | RAN binding protein 6 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RPL39L | ribosomal protein L39-like |
| SALL2 | spalt-like transcription factor 2 |
| SARAF | store-operated calcium entry-associated regulatory factor |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) |
| SKI | SKI proto-oncogene |
| SLC35E3 | solute carrier family 35, member E3 |
| SLC38A6 | solute carrier family 38, member 6 |
| SRBD1 | S1 RNA binding domain 1 |
| SRP54 | signal recognition particle 54kDa |
| TBPL1 | TBP-like 1 |
| TFB2M | transcription factor B2, mitochondrial |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TM9SF2 | transmembrane 9 superfamily member 2 |
| TMEM147 | transmembrane protein 147 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| UTP11L | UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) |
| VDAC2 | voltage-dependent anion channel 2 |
| ZBTB11 | zinc finger and BTB domain containing 11 |
| ZFC3H1 | zinc finger, C3H1-type containing |
| ZNF189 | zinc finger protein 189 |
| ZNF217 | zinc finger protein 217 |
| ZNF250 | zinc finger protein 250 |
| ZNF562 | zinc finger protein 562 |
