| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the metronidazole-2003 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ACTN2 | actinin, alpha 2 |
| ADCY9 | adenylate cyclase 9 |
| ADORA2B | adenosine A2b receptor |
| AFF2 | AF4/FMR2 family, member 2 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ANKRD12 | ankyrin repeat domain 12 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APOM | apolipoprotein M |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C2CD2L | C2CD2-like |
| CA7 | carbonic anhydrase VII |
| CCHCR1 | coiled-coil alpha-helical rod protein 1 |
| CDC14B | cell division cycle 14B |
| CFAP74 | cilia and flagella associated protein 74 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLIC4 | chloride intracellular channel 4 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CYB561 | cytochrome b561 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| ERCC6 | excision repair cross-complementation group 6 |
| FAM89B | family with sequence similarity 89, member B |
| FBXO41 | F-box protein 41 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GALR3 | galanin receptor 3 |
| GLS | glutaminase |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GRB7 | growth factor receptor-bound protein 7 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa |
| GTPBP1 | GTP binding protein 1 |
| HBB | hemoglobin, beta |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| INE1 | inactivation escape 1 (non-protein coding) |
| INTS7 | integrator complex subunit 7 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KIF5A | kinesin family member 5A |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT86 | keratin 86, type II |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LMNA | lamin A/C |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGED2 | melanoma antigen family D2 |
| MAGEF1 | melanoma antigen family F1 |
| MAP1A | microtubule-associated protein 1A |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MID2 | midline 2 |
| MOB3B | MOB kinase activator 3B |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXD4 | MAX dimerization protein 4 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NKX3-1 | NK3 homeobox 1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NXPH3 | neurexophilin 3 |
| OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
| PCDH7 | protocadherin 7 |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PGC | progastricsin (pepsinogen C) |
| PIGR | polymeric immunoglobulin receptor |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PPP1R17 | protein phosphatase 1, regulatory subunit 17 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRR14L | proline rich 14-like |
| PVR | poliovirus receptor |
| RNF39 | ring finger protein 39 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RWDD3 | RWD domain containing 3 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SNX11 | sorting nexin 11 |
| SOD3 | superoxide dismutase 3, extracellular |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| STAT4 | signal transducer and activator of transcription 4 |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SUOX | sulfite oxidase |
| SYN2 | synapsin II |
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) |
| TMEM74B | transmembrane protein 74B |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| UNC5B | unc-5 homolog B (C. elegans) |
| USF2 | upstream transcription factor 2, c-fos interacting |
| YIPF4 | Yip1 domain family, member 4 |
| ZNF783 | zinc finger family member 783 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| AGO3 | argonaute RISC catalytic component 3 |
| AHR | aryl hydrocarbon receptor |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APH1A | APH1A gamma secretase subunit |
| APOBR | apolipoprotein B receptor |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BBC3 | BCL2 binding component 3 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| BCL10 | B-cell CLL/lymphoma 10 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CDC73 | cell division cycle 73 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 |
| CLK3 | CDC-like kinase 3 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CNPY3 | canopy FGF signaling regulator 3 |
| CTSK | cathepsin K |
| DBF4 | DBF4 zinc finger |
| DENND4A | DENN/MADD domain containing 4A |
| DERA | deoxyribose-phosphate aldolase (putative) |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DMXL1 | Dmx-like 1 |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| FAM206A | family with sequence similarity 206, member A |
| FBXW4 | F-box and WD repeat domain containing 4 |
| FOXM1 | forkhead box M1 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HARS | histidyl-tRNA synthetase |
| HIRA | histone cell cycle regulator |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial |
| IFITM3 | interferon induced transmembrane protein 3 |
| IMPACT | impact RWD domain protein |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KCTD9 | potassium channel tetramerization domain containing 9 |
| KIFC1 | kinesin family member C1 |
| KIZ | kizuna centrosomal protein |
| KRBOX4 | KRAB box domain containing 4 |
| LBR | lamin B receptor |
| LMAN2L | lectin, mannose-binding 2-like |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAPK10 | mitogen-activated protein kinase 10 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| MXRA7 | matrix-remodelling associated 7 |
| NADSYN1 | NAD synthetase 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NMI | N-myc (and STAT) interactor |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PRKCD | protein kinase C, delta |
| PRRC1 | proline-rich coiled-coil 1 |
| RAB21 | RAB21, member RAS oncogene family |
| RAB4B | RAB4B, member RAS oncogene family |
| RNF144A | ring finger protein 144A |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SMYD5 | SMYD family member 5 |
| SRP54 | signal recognition particle 54kDa |
| STAC | SH3 and cysteine rich domain |
| TCTN2 | tectonic family member 2 |
| TEFM | transcription elongation factor, mitochondrial |
| TEX30 | testis expressed 30 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGIF1 | TGFB-induced factor homeobox 1 |
| THOP1 | thimet oligopeptidase 1 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TNRC6B | trinucleotide repeat containing 6B |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRAIP | TRAF interacting protein |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP32 | ubiquitin specific peptidase 32 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VILL | villin-like |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| WDR47 | WD repeat domain 47 |
| WDR91 | WD repeat domain 91 |
| ZBTB5 | zinc finger and BTB domain containing 5 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZDHHC6 | zinc finger, DHHC-type containing 6 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF408 | zinc finger protein 408 |
