| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the metronidazole-4023 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ADCK2 | aarF domain containing kinase 2 |
| ADD2 | adducin 2 (beta) |
| ADPRH | ADP-ribosylarginine hydrolase |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| C11ORF1 | chromosome 11 open reading frame 1 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C22ORF31 | chromosome 22 open reading frame 31 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK13 | cyclin-dependent kinase 13 |
| CDY1 | chromodomain protein, Y-linked, 1 |
| CES3 | carboxylesterase 3 |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CLCA2 | chloride channel accessory 2 |
| COL1A2 | collagen, type I, alpha 2 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CST1 | cystatin SN |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DTNA | dystrobrevin, alpha |
| EDNRA | endothelin receptor type A |
| EPS8L1 | EPS8-like 1 |
| FAM134B | family with sequence similarity 134, member B |
| FAS | Fas cell surface death receptor |
| FGFR4 | fibroblast growth factor receptor 4 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FRMD4B | FERM domain containing 4B |
| GGT1 | gamma-glutamyltransferase 1 |
| GPATCH4 | G patch domain containing 4 |
| HBS1L | HBS1-like translational GTPase |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIST1H2BL | histone cluster 1, H2bl |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IHH | indian hedgehog |
| KIAA0226L | KIAA0226-like |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KRT7 | keratin 7, type II |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LOXL3 | lysyl oxidase-like 3 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MEP1B | meprin A, beta |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NOTCH3 | notch 3 |
| NOX1 | NADPH oxidase 1 |
| NRN1 | neuritin 1 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OCM2 | oncomodulin 2 |
| OMD | osteomodulin |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PAPPA2 | pappalysin 2 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PASK | PAS domain containing serine/threonine kinase |
| PDE11A | phosphodiesterase 11A |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PRG3 | proteoglycan 3 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| RAB33A | RAB33A, member RAS oncogene family |
| RFC1 | replication factor C (activator 1) 1, 145kDa |
| RHO | rhodopsin |
| RNF39 | ring finger protein 39 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SGSM3 | small G protein signaling modulator 3 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| SULF1 | sulfatase 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TADA2A | transcriptional adaptor 2A |
| TAS2R16 | taste receptor, type 2, member 16 |
| TBRG4 | transforming growth factor beta regulator 4 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| THBD | thrombomodulin |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TPH1 | tryptophan hydroxylase 1 |
| TSPAN9 | tetraspanin 9 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| XYLB | xylulokinase homolog (H. influenzae) |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALS2CL | ALS2 C-terminal like |
| ARC | activity-regulated cytoskeleton-associated protein |
| AXIN1 | axin 1 |
| B9D2 | B9 protein domain 2 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA9 | carbonic anhydrase IX |
| CCDC71 | coiled-coil domain containing 71 |
| CCNJL | cyclin J-like |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHI3L2 | chitinase 3-like 2 |
| CHPF | chondroitin polymerizing factor |
| CISH | cytokine inducible SH2-containing protein |
| CLDN15 | claudin 15 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CRMP1 | collapsin response mediator protein 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDN | dendrin |
| DEAF1 | DEAF1 transcription factor |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPN1 | epsin 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXO5 | exonuclease 5 |
| EXOC6B | exocyst complex component 6B |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM50B | family with sequence similarity 50, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FKBP5 | FK506 binding protein 5 |
| FLCN | folliculin |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRM4 | glutamate receptor, metabotropic 4 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC7 | histone deacetylase 7 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1D | histone cluster 1, H1d |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| ITGB7 | integrin, beta 7 |
| ITPKA | inositol-trisphosphate 3-kinase A |
| LMTK1 | lemur tail kinase 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP3K7CL | MAP3K7 C-terminal like |
| MNMIP1 | manchette microtubule inner protein 1 |
| MYLK | myosin light chain kinase |
| MYO1E | myosin IE |
| NCS1 | neuronal calcium sensor 1 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PDE8B | phosphodiesterase 8B |
| PLD3 | phospholipase D family, member 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLH | polymerase (DNA directed), eta |
| POLL | polymerase (DNA directed), lambda |
| POM121 | POM121 transmembrane nucleoporin |
| PRR7 | proline rich 7 (synaptic) |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUSC2 | RUN and SH3 domain containing 2 |
| S100A3 | S100 calcium binding protein A3 |
| SCAI | suppressor of cancer cell invasion |
| SCD5 | stearoyl-CoA desaturase 5 |
| SH2D2A | SH2 domain containing 2A |
| SIRAL2 | SIR2 antiphage like 2 |
| SLAMF7 | SLAM family member 7 |
| SLC22A14 | solute carrier family 22, member 14 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPATA1 | spermatogenesis associated 1 |
| SSTR4 | somatostatin receptor 4 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR4 | WD repeat domain 4 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF528 | zinc finger protein 528 |
