| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the metronidazole-4141 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOT7 | acyl-CoA thioesterase 7 |
| ACTN2 | actinin, alpha 2 |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADCK2 | aarF domain containing kinase 2 |
| ADCY10 | adenylate cyclase 10 (soluble) |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALOXE3 | arachidonate lipoxygenase 3 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP10B | ATPase, class V, type 10B |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| ATXN2L | ataxin 2-like |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C4BPA | complement component 4 binding protein, alpha |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CARD14 | caspase recruitment domain family, member 14 |
| CD300C | CD300c molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD5 | CD5 molecule |
| CD58 | CD58 molecule |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLEC2B | C-type lectin domain family 2, member B |
| COL1A1 | collagen, type I, alpha 1 |
| CRYGD | crystallin, gamma D |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| DOK4 | docking protein 4 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ECE1 | endothelin converting enzyme 1 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EFNB3 | ephrin-B3 |
| FAM171A1 | family with sequence similarity 171, member A1 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| GYPB | glycophorin B (MNS blood group) |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HOXA7 | homeobox A7 |
| HPX | hemopexin |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL7R | interleukin 7 receptor |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KERA | keratocan |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KRT75 | keratin 75, type II |
| LAMA4 | laminin, alpha 4 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LRRC20 | leucine rich repeat containing 20 |
| LRRC6 | leucine rich repeat containing 6 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| METTL16 | methyltransferase like 16 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MMP25 | matrix metallopeptidase 25 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NKX3-2 | NK3 homeobox 2 |
| NOL10 | nucleolar protein 10 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| PAQR5 | progestin and adipoQ receptor family member V |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PON3 | paraoxonase 3 |
| PRMT2IP | PRMT2 interacting protein |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNF32 | ring finger protein 32 |
| RORC | RAR-related orphan receptor C |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SECTM1 | secreted and transmembrane 1 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SH3BP2 | SH3-domain binding protein 2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SKAP1 | src kinase associated phosphoprotein 1 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SP100 | SP100 nuclear antigen |
| SPEF1 | sperm flagellar 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TBCD | tubulin folding cofactor D |
| TBX5 | T-box 5 |
| TP63 | tumor protein p63 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| WSCD1 | WSC domain containing 1 |
| ZNF639 | zinc finger protein 639 |
| ZNF646 | zinc finger protein 646 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ALPK1 | alpha-kinase 1 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CA11 | carbonic anhydrase XI |
| CCDC186 | coiled-coil domain containing 186 |
| CCNT1 | cyclin T1 |
| CD34 | CD34 molecule |
| CD80 | CD80 molecule |
| CD82 | CD82 molecule |
| CFAP69 | cilia and flagella associated protein 69 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CPA4 | carboxypeptidase A4 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DRD1 | dopamine receptor D1 |
| ECM1 | extracellular matrix protein 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERCC4 | excision repair cross-complementation group 4 |
| FADS2 | fatty acid desaturase 2 |
| FAM46C | family with sequence similarity 46, member C |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GAMT | guanidinoacetate N-methyltransferase |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLB1L | galactosidase, beta 1-like |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2AK | histone cluster 1, H2ak |
| HMOX1 | heme oxygenase 1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IBSP | integrin-binding sialoprotein |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0894 | KIAA0894 protein |
| KRT31 | keratin 31, type I |
| KRT83 | keratin 83, type II |
| LARS | leucyl-tRNA synthetase |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LRRC15 | leucine rich repeat containing 15 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NDE1 | nudE neurodevelopment protein 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NLRX1 | NLR family member X1 |
| NPY4R | neuropeptide Y receptor Y4 |
| PCDHGB6 | protocadherin gamma subfamily B, 6 |
| PDE12 | phosphodiesterase 12 |
| PICK1 | protein interacting with PRKCA 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PRAMEF11 | PRAME family member 11 |
| PRPF19 | pre-mRNA processing factor 19 |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RAB30 | RAB30, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RFXAP | regulatory factor X-associated protein |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF122 | ring finger protein 122 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCG2 | secretogranin II |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| ST5 | suppression of tumorigenicity 5 |
| STAG3 | stromal antigen 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TEP1 | telomerase-associated protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TIPRL | TOR signaling pathway regulator |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMEM19 | transmembrane protein 19 |
| TRIM16 | tripartite motif containing 16 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| USP36 | ubiquitin specific peptidase 36 |
| WDR76 | WD repeat domain 76 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF205 | zinc finger protein 205 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF41 | zinc finger protein 41 |
| ZNF652 | zinc finger protein 652 |
| ZNF696 | zinc finger protein 696 |
