| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the metyrapone-5667 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADRB1 | adrenoceptor beta 1 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AMELX | amelogenin, X-linked |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| BAX | BCL2-associated X protein |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| BLNK | B-cell linker |
| BTG2 | BTG family, member 2 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCNK | cyclin K |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP250 | centrosomal protein 250kDa |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLCA2 | chloride channel accessory 2 |
| CNTN5 | contactin 5 |
| COL10A1 | collagen, type X, alpha 1 |
| COL9A3 | collagen, type IX, alpha 3 |
| CORO2B | coronin, actin binding protein, 2B |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CUL7 | cullin 7 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FAS | Fas cell surface death receptor |
| FBXO2 | F-box protein 2 |
| FCMR | Fc fragment of IgM receptor |
| FHL1 | four and a half LIM domains 1 |
| FLJ11292 | |
| FOXG1 | forkhead box G1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GH1 | growth hormone 1 |
| GK | glycerol kinase |
| GLRA2 | glycine receptor, alpha 2 |
| GPR21 | G protein-coupled receptor 21 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HDAC9 | histone deacetylase 9 |
| HGD | homogentisate 1,2-dioxygenase |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| HRASLS2 | HRAS-like suppressor 2 |
| IDS | iduronate 2-sulfatase |
| IL1B | interleukin 1, beta |
| ITGB7 | integrin, beta 7 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KLK13 | kallikrein-related peptidase 13 |
| LIMK2 | LIM domain kinase 2 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC441601 | septin 7 pseudogene |
| LOXL3 | lysyl oxidase-like 3 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| NF1 | neurofibromin 1 |
| NHLH2 | nescient helix loop helix 2 |
| OLIG2 | oligodendrocyte lineage transcription factor 2 |
| PADI3 | peptidyl arginine deiminase, type III |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2G5 | phospholipase A2, group V |
| PLCD1 | phospholipase C, delta 1 |
| PLXNB3 | plexin B3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRDM11 | PR domain containing 11 |
| PRLR | prolactin receptor |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| RAI2 | retinoic acid induced 2 |
| RASA3 | RAS p21 protein activator 3 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SESN1 | sestrin 1 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SYNGR1 | synaptogyrin 1 |
| SYNPO | synaptopodin |
| SYT12 | synaptotagmin XII |
| TECTA | tectorin alpha |
| TEX41 | testis expressed 41 (non-protein coding) |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TUBB2B | tubulin, beta 2B class IIb |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VNN2 | vanin 2 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF76 | zinc finger protein 76 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMC6 | armadillo repeat containing 6 |
| ARRB1 | arrestin, beta 1 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATP10D | ATPase, class V, type 10D |
| BAG4 | BCL2-associated athanogene 4 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BMP4 | bone morphogenetic protein 4 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCNE2 | cyclin E2 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDHR2 | cadherin-related family member 2 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CEP162 | centrosomal protein 162kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLSPN | claspin |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| E2F8 | E2F transcription factor 8 |
| EDAR | ectodysplasin A receptor |
| EFNA3 | ephrin-A3 |
| FAM198B | family with sequence similarity 198, member B |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXO5 | F-box protein 5 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2BJ | histone cluster 1, H2bj |
| HOXD11 | homeobox D11 |
| JMJD4 | jumonji domain containing 4 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LAMA3 | laminin, alpha 3 |
| LHX1 | LIM homeobox 1 |
| LOC257152 | uncharacterized LOC257152 |
| LRRC42 | leucine rich repeat containing 42 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MATK | megakaryocyte-associated tyrosine kinase |
| MDM4 | MDM4, p53 regulator |
| METTL16 | methyltransferase like 16 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| NEK11 | NIMA-related kinase 11 |
| NES | nestin |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OSMR | oncostatin M receptor |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| S100A9 | S100 calcium binding protein A9 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| STAG3 | stromal antigen 3 |
| STIM1 | stromal interaction molecule 1 |
| TBR1 | T-box, brain, 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TMEM19 | transmembrane protein 19 |
| TMEM53 | transmembrane protein 53 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TRAF2 | TNF receptor-associated factor 2 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRIM25 | tripartite motif containing 25 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TWISTNB | TWIST neighbor |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VIM | vimentin |
| WDR18 | WD repeat domain 18 |
| WDR33 | WD repeat domain 33 |
| WDR4 | WD repeat domain 4 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF165 | zinc finger protein 165 |
| ZNF219 | zinc finger protein 219 |
| ZNF510 | zinc finger protein 510 |
| ZNF804A | zinc finger protein 804A |