| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the metyrapone-6447 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACTL8 | actin-like 8 |
| ADAM20 | ADAM metallopeptidase domain 20 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 |
| ARTN | artemin |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP10A | ATPase, class V, type 10A |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD82 | CD82 molecule |
| CDC25A | cell division cycle 25A |
| CDK3 | cyclin-dependent kinase 3 |
| CEP350 | centrosomal protein 350kDa |
| CLTA | clathrin, light chain A |
| COMT | catechol-O-methyltransferase |
| CPB2 | carboxypeptidase B2 (plasma) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DFNB31 | deafness, autosomal recessive 31 |
| DICER1 | dicer 1, ribonuclease type III |
| EDNRB | endothelin receptor type B |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| EMP3 | epithelial membrane protein 3 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| FGB | fibrinogen beta chain |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FOSL2 | FOS-like antigen 2 |
| FOXL1 | forkhead box L1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GAL | galanin/GMAP prepropeptide |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSPT1 | G1 to S phase transition 1 |
| HFE | hemochromatosis |
| HOXA10 | homeobox A10 |
| HPX | hemopexin |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| INO80B | INO80 complex subunit B |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KIAA0368 | KIAA0368 |
| KIF21B | kinesin family member 21B |
| KIF25 | kinesin family member 25 |
| KLK8 | kallikrein-related peptidase 8 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT17 | keratin 17, type I |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRRC14 | leucine rich repeat containing 14 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAB21L1 | mab-21-like 1 (C. elegans) |
| MALL | mal, T-cell differentiation protein-like |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MIP | major intrinsic protein of lens fiber |
| MRC2 | mannose receptor, C type 2 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NIPAL3 | NIPA-like domain containing 3 |
| NOX1 | NADPH oxidase 1 |
| NPR3 | natriuretic peptide receptor 3 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NXF2 | nuclear RNA export factor 2 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PIGR | polymeric immunoglobulin receptor |
| PLD3 | phospholipase D family, member 3 |
| POU2F2 | POU class 2 homeobox 2 |
| PPEF1 | protein phosphatase, EF-hand calcium binding domain 1 |
| PRAMEF11 | PRAME family member 11 |
| PRKCA | protein kinase C, alpha |
| PTAFR | platelet-activating factor receptor |
| R3HDM1 | R3H domain containing 1 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SHOX2 | short stature homeobox 2 |
| SLC45A2 | solute carrier family 45, member 2 |
| SLC6A16 | solute carrier family 6, member 16 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| TEX40 | testis expressed 40 |
| TGM3 | transglutaminase 3 |
| TMEM259 | transmembrane protein 259 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TSR3 | TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) |
| UNC5B | unc-5 homolog B (C. elegans) |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZNF304 | zinc finger protein 304 |
| ZNF384 | zinc finger protein 384 |
| Symbol | Name |
|---|---|
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ASPN | asporin |
| ATXN2 | ataxin 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLDN4 | claudin 4 |
| CORO2A | coronin, actin binding protein, 2A |
| CXXC4 | CXXC finger protein 4 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC6 | excision repair cross-complementation group 6 |
| ERF | Ets2 repressor factor |
| F2R | coagulation factor II (thrombin) receptor |
| FAM155A | family with sequence similarity 155, member A |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FLT4 | fms-related tyrosine kinase 4 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GPC3 | glypican 3 |
| GPR87 | G protein-coupled receptor 87 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIRA | histone cell cycle regulator |
| HIST1H2AM | histone cluster 1, H2am |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMOX1 | heme oxygenase 1 |
| HOXC8 | homeobox C8 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL15RA | interleukin 15 receptor, alpha |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM8 | lysine (K)-specific demethylase 8 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC729164 | hCG1732469 |
| LRRC20 | leucine rich repeat containing 20 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MCC | mutated in colorectal cancers |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MED31 | mediator complex subunit 31 |
| NBEAL2 | neurobeachin-like 2 |
| NCALD | neurocalcin delta |
| NEK11 | NIMA-related kinase 11 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| P3H1 | prolyl 3-hydroxylase 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLD2 | phospholipase D2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POLH | polymerase (DNA directed), eta |
| RCAN3 | RCAN family member 3 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SFRP5 | secreted frizzled-related protein 5 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAOK1 | TAO kinase 1 |
| TCTN1 | tectonic family member 1 |
| THBS3 | thrombospondin 3 |
| TMEM254 | transmembrane protein 254 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOM1 | target of myb1 (chicken) |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSPAN1 | tetraspanin 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VASP | vasodilator-stimulated phosphoprotein |
| VIM | vimentin |
| WDR91 | WD repeat domain 91 |
| WLS | wntless Wnt ligand secretion mediator |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF254 | zinc finger protein 254 |
| ZNF350 | zinc finger protein 350 |
| ZNF428 | zinc finger protein 428 |
| ZNF480 | zinc finger protein 480 |
| ZNF492 | zinc finger protein 492 |
| ZNF74 | zinc finger protein 74 |
| ZNF862 | zinc finger protein 862 |
