| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the mevalolactone-5738 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ACRV1 | acrosomal vesicle protein 1 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMH | anti-Mullerian hormone |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| APC2 | adenomatosis polyposis coli 2 |
| APOE | apolipoprotein E |
| APOM | apolipoprotein M |
| ARRB1 | arrestin, beta 1 |
| ARTN | artemin |
| ATP9A | ATPase, class II, type 9A |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCDC71 | coiled-coil domain containing 71 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLDN3 | claudin 3 |
| CNPY4 | canopy FGF signaling regulator 4 |
| COL1A1 | collagen, type I, alpha 1 |
| COL7A1 | collagen, type VII, alpha 1 |
| COMT | catechol-O-methyltransferase |
| COPE | coatomer protein complex, subunit epsilon |
| CREM | cAMP responsive element modulator |
| CTIF | CBP80/20-dependent translation initiation factor |
| CYBRD1 | cytochrome b reductase 1 |
| DMWD | dystrophia myotonica, WD repeat containing |
| DMXL2 | Dmx-like 2 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DTNA | dystrobrevin, alpha |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EGFR | epidermal growth factor receptor |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FHIT | fragile histidine triad |
| FKBP15 | FK506 binding protein 15, 133kDa |
| GAS8 | growth arrest-specific 8 |
| GPC3 | glypican 3 |
| GPM6A | glycoprotein M6A |
| GPX3 | glutathione peroxidase 3 |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HOOK1 | hook microtubule-tethering protein 1 |
| HSF1 | heat shock transcription factor 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| ID2B | inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene) |
| IZUMO4 | IZUMO family member 4 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIAA0319L | KIAA0319-like |
| KIAA1109 | KIAA1109 |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| KLHL25 | kelch-like family member 25 |
| LAMB4 | laminin, beta 4 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MST1L | macrophage stimulating 1-like |
| ODF2 | outer dense fiber of sperm tails 2 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PCDHGA1 | protocadherin gamma subfamily A, 1 |
| POSTN | periostin, osteoblast specific factor |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| RAB6B | RAB6B, member RAS oncogene family |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RHEB | Ras homolog enriched in brain |
| RSU1 | Ras suppressor protein 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINA4 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SP110 | SP110 nuclear body protein |
| ST7L | suppression of tumorigenicity 7 like |
| TBR1 | T-box, brain, 1 |
| TGFA | transforming growth factor, alpha |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRD | T cell receptor delta locus |
| TULP2 | tubby like protein 2 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| YBX3 | Y box binding protein 3 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF500 | zinc finger protein 500 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| CA8 | carbonic anhydrase VIII |
| CCDC9 | coiled-coil domain containing 9 |
| CDK3 | cyclin-dependent kinase 3 |
| CDK6 | cyclin-dependent kinase 6 |
| CDON | cell adhesion associated, oncogene regulated |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CLDN11 | claudin 11 |
| CLSPN | claspin |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DUSP8 | dual specificity phosphatase 8 |
| EFNB1 | ephrin-B1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FER | fer (fps/fes related) tyrosine kinase |
| FOXA1 | forkhead box A1 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GAB2 | GRB2-associated binding protein 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLB1L | galactosidase, beta 1-like |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HDAC4 | histone deacetylase 4 |
| HIRA | histone cell cycle regulator |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H3B | histone cluster 1, H3b |
| HOXC4 | homeobox C4 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFNA14 | interferon, alpha 14 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL12A | interleukin 12A |
| IL6 | interleukin 6 |
| IPO8 | importin 8 |
| IREB2 | iron-responsive element binding protein 2 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LMNB1 | lamin B1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAGEB2 | melanoma antigen family B2 |
| MAGEF1 | melanoma antigen family F1 |
| MDFI | MyoD family inhibitor |
| MED22 | mediator complex subunit 22 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MTA2 | metastasis associated 1 family, member 2 |
| MX1 | MX dynamin-like GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| NABP1 | nucleic acid binding protein 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDRG4 | NDRG family member 4 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUBP2 | nucleotide binding protein 2 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIDD1 | p53-induced death domain protein 1 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNF122 | ring finger protein 122 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SDC3 | syndecan 3 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SHPK | sedoheptulokinase |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TEAD3 | TEA domain family member 3 |
| TENM1 | teneurin transmembrane protein 1 |
| TH | tyrosine hydroxylase |
| TIGD6 | tigger transposable element derived 6 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| VEGFB | vascular endothelial growth factor B |
| VGF | VGF nerve growth factor inducible |
| VN1R1 | vomeronasal 1 receptor 1 |
| WDR78 | WD repeat domain 78 |
| YY2 | YY2 transcription factor |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF276 | zinc finger protein 276 |
| ZNF480 | zinc finger protein 480 |
| ZNF668 | zinc finger protein 668 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
