mevastatin Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group and in which the lactone moiety has been hydrolysed to the corresponding delta-hydroxy-carboxylic acid. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. (Chemical Entities of Biological Interest Ontology, CHEBI_34848)
Similar Terms
Downloads & Tools

Genes

2 genes co-occuring with the biological term mevastatin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
PPARG peroxisome proliferator-activated receptor gamma