| Dataset | Guide to Pharmacology Chemical Ligands of Receptors |
| Category | physical interactions |
| Type | ligand (chemical) |
| Description | A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group and in which the lactone moiety has been hydrolysed to the corresponding delta-hydroxy-carboxylic acid. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. (Chemical Entities of Biological Interest Ontology, CHEBI_34848) |
| External Link | http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=3031 |
| Similar Terms | |
| Downloads & Tools |
1 receptors of the mevastatin ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.
| Symbol | Name |
|---|---|
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
