| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the mexiletine-2324 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADORA1 | adenosine A1 receptor |
| ALDOB | aldolase B, fructose-bisphosphate |
| APC | adenomatous polyposis coli |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAV2 | caveolin 2 |
| CD300A | CD300a molecule |
| CD58 | CD58 molecule |
| CD82 | CD82 molecule |
| CDC25C | cell division cycle 25C |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CPA4 | carboxypeptidase A4 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTRL | chymotrypsin-like |
| DCN | decorin |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DYM | dymeclin |
| FAM110D | family with sequence similarity 110, member D |
| FANCA | Fanconi anemia, complementation group A |
| FBLN1 | fibulin 1 |
| FCMR | Fc fragment of IgM receptor |
| FGF6 | fibroblast growth factor 6 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| FRAS1 | Fraser extracellular matrix complex subunit 1 |
| FRMD1 | FERM domain containing 1 |
| GAB1 | GRB2-associated binding protein 1 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GPATCH4 | G patch domain containing 4 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GYPB | glycophorin B (MNS blood group) |
| HOXC5 | homeobox C5 |
| IL9R | interleukin 9 receptor |
| JAM3 | junctional adhesion molecule 3 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIAA1456 | KIAA1456 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAT2 | linker for activation of T cells family, member 2 |
| LDLR | low density lipoprotein receptor |
| LENEP | lens epithelial protein |
| LHX2 | LIM homeobox 2 |
| LOXL3 | lysyl oxidase-like 3 |
| MAOB | monoamine oxidase B |
| MED25 | mediator complex subunit 25 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MOB3B | MOB kinase activator 3B |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTRF1L | mitochondrial translational release factor 1-like |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NOX1 | NADPH oxidase 1 |
| PCDH1 | protocadherin 1 |
| PER1 | period circadian clock 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| RASL11B | RAS-like, family 11, member B |
| RHBDD3 | rhomboid domain containing 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RUNDC3A | RUN domain containing 3A |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SC5D | sterol-C5-desaturase |
| SCRG1 | stimulator of chondrogenesis 1 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SGCE | sarcoglycan, epsilon |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SNCAIP | synuclein, alpha interacting protein |
| SORCS3 | sortilin-related VPS10 domain containing receptor 3 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPAG8 | sperm associated antigen 8 |
| STAC | SH3 and cysteine rich domain |
| STS | steroid sulfatase (microsomal), isozyme S |
| TBC1D2 | TBC1 domain family, member 2 |
| TBL2 | transducin (beta)-like 2 |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| THBS4 | thrombospondin 4 |
| THRB | thyroid hormone receptor, beta |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TRIM14 | tripartite motif containing 14 |
| TRIM29 | tripartite motif containing 29 |
| TUBBP5 | tubulin, beta pseudogene 5 |
| UPK3A | uroplakin 3A |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZNF423 | zinc finger protein 423 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCORL1 | BCL6 corepressor-like 1 |
| C11ORF57 | chromosome 11 open reading frame 57 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C5AR2 | complement component 5a receptor 2 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CASZ1 | castor zinc finger 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNK | cyclin K |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD83 | CD83 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOC2A | double C2-like domains, alpha |
| DOCK4 | dedicator of cytokinesis 4 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP5 | FK506 binding protein 5 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXI1 | forkhead box I1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPATCH2L | G patch domain containing 2-like |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HDAC11 | histone deacetylase 11 |
| HDAC5 | histone deacetylase 5 |
| HIST1H3B | histone cluster 1, H3b |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IPO8 | importin 8 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIFAP3 | kinesin-associated protein 3 |
| KLHL21 | kelch-like family member 21 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCC | mutated in colorectal cancers |
| MED15 | mediator complex subunit 15 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| NYNRIN | NYN domain and retroviral integrase containing |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PMEL | premelanosome protein |
| PRODH | proline dehydrogenase (oxidase) 1 |
| RAB3D | RAB3D, member RAS oncogene family |
| ROM1 | retinal outer segment membrane protein 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SDC3 | syndecan 3 |
| SETD1A | SET domain containing 1A |
| SH2B3 | SH2B adaptor protein 3 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SLN | sarcolipin |
| SMIM14 | small integral membrane protein 14 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| TBC1D17 | TBC1 domain family, member 17 |
| TLR2 | toll-like receptor 2 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMC7 | transmembrane channel-like 7 |
| TMEM19 | transmembrane protein 19 |
| TMEM39B | transmembrane protein 39B |
| TOM1 | target of myb1 (chicken) |
| TRIM21 | tripartite motif containing 21 |
| TSPYL2 | TSPY-like 2 |
| TUBG2 | tubulin, gamma 2 |
| UBQLN4 | ubiquilin 4 |
| VLDLR | very low density lipoprotein receptor |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF250 | zinc finger protein 250 |
| ZNF34 | zinc finger protein 34 |
| ZNF350 | zinc finger protein 350 |
| ZNF468 | zinc finger protein 468 |
| ZNF606 | zinc finger protein 606 |
| ZNF668 | zinc finger protein 668 |
