| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the mexiletine-2364 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BLVRA | biliverdin reductase A |
| BMP7 | bone morphogenetic protein 7 |
| CA12 | carbonic anhydrase XII |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC85B | coiled-coil domain containing 85B |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD38 | CD38 molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK13 | cyclin-dependent kinase 13 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CELF1 | CUGBP, Elav-like family member 1 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| CNGB1 | cyclic nucleotide gated channel beta 1 |
| CUL3 | cullin 3 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DNASE2 | deoxyribonuclease II, lysosomal |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBXO31 | F-box protein 31 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GSPT1 | G1 to S phase transition 1 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL1RN | interleukin 1 receptor antagonist |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa |
| IRF7 | interferon regulatory factor 7 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KIAA0753 | KIAA0753 |
| KRT81 | keratin 81, type II |
| LMF1 | lipase maturation factor 1 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| MAX | MYC associated factor X |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MTMR3 | myotubularin related protein 3 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NDRG3 | NDRG family member 3 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NF2 | neurofibromin 2 (merlin) |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPR2 | natriuretic peptide receptor 2 |
| OGFR | opioid growth factor receptor |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDH12 | protocadherin 12 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PFDN6 | prefoldin subunit 6 |
| PIP | prolactin-induced protein |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PKP3 | plakophilin 3 |
| PLSCR3 | phospholipid scramblase 3 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| PRPF6 | pre-mRNA processing factor 6 |
| PRY | PTPN13-like, Y-linked |
| PSEN1 | presenilin 1 |
| REST | RE1-silencing transcription factor |
| RGS3 | regulator of G-protein signaling 3 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RNF19B | ring finger protein 19B |
| SAA4 | serum amyloid A4, constitutive |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SMAD5 | SMAD family member 5 |
| SOCS2 | suppressor of cytokine signaling 2 |
| SPATA20 | spermatogenesis associated 20 |
| SPRR1A | small proline-rich protein 1A |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBX10 | T-box 10 |
| TEF | thyrotrophic embryonic factor |
| TEX261 | testis expressed 261 |
| TJP1 | tight junction protein 1 |
| TLE3 | transducin-like enhancer of split 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TTN | titin |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| USP48 | ubiquitin specific peptidase 48 |
| WDR1 | WD repeat domain 1 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF589 | zinc finger protein 589 |
| ZNF696 | zinc finger protein 696 |
| ZNF783 | zinc finger family member 783 |
| ZNF787 | zinc finger protein 787 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ANXA3 | annexin A3 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARRB2 | arrestin, beta 2 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| AVPI1 | arginine vasopressin-induced 1 |
| BAX | BCL2-associated X protein |
| BBS10 | Bardet-Biedl syndrome 10 |
| BCL2L2 | BCL2-like 2 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD1D | CD1d molecule |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CDK6 | cyclin-dependent kinase 6 |
| CENPB | centromere protein B, 80kDa |
| CENPT | centromere protein T |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLEC7A | C-type lectin domain family 7, member A |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CSF1R | colony stimulating factor 1 receptor |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DBF4B | DBF4 zinc finger B |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DSPP | dentin sialophosphoprotein |
| DVL1 | dishevelled segment polarity protein 1 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| GMIP | GEM interacting protein |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR22 | G protein-coupled receptor 22 |
| GPR65 | G protein-coupled receptor 65 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIRA | histone cell cycle regulator |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2BF | histone cluster 1, H2bf |
| ICK | intestinal cell (MAK-like) kinase |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| JUNB | jun B proto-oncogene |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLF13 | Kruppel-like factor 13 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LOC100127972 | uncharacterized LOC100127972 |
| LOC729164 | hCG1732469 |
| MAGEB2 | melanoma antigen family B2 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MYL5 | myosin, light chain 5, regulatory |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLA2G15 | phospholipase A2, group XV |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PRMT7 | protein arginine methyltransferase 7 |
| PSKH1 | protein serine kinase H1 |
| RAB5B | RAB5B, member RAS oncogene family |
| RCAN3 | RCAN family member 3 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SMA4 | glucuronidase, beta pseudogene |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STK25 | serine/threonine kinase 25 |
| SYNJ2BP | synaptojanin 2 binding protein |
| TIGD6 | tigger transposable element derived 6 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM110 | transmembrane protein 110 |
| TMEM212 | transmembrane protein 212 |
| TRIM21 | tripartite motif containing 21 |
| TSPAN14 | tetraspanin 14 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| USP19 | ubiquitin specific peptidase 19 |
| VILL | villin-like |
| WDR60 | WD repeat domain 60 |
| WWC3 | WWC family member 3 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF250 | zinc finger protein 250 |
| ZNF426 | zinc finger protein 426 |
| ZNF468 | zinc finger protein 468 |
| ZNF629 | zinc finger protein 629 |
| ZNF668 | zinc finger protein 668 |
| ZNF701 | zinc finger protein 701 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
