| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the mexiletine-3781 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| ADAP1 | ArfGAP with dual PH domains 1 |
| AGXT | alanine-glyoxylate aminotransferase |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ALPP | alkaline phosphatase, placental |
| AMPH | amphiphysin |
| ATN1 | atrophin 1 |
| ATXN3L | ataxin 3-like |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| CALHM2 | calcium homeostasis modulator 2 |
| CASC1 | cancer susceptibility candidate 1 |
| CD247 | CD247 molecule |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHI3L2 | chitinase 3-like 2 |
| CLDN1 | claudin 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| COL1A1 | collagen, type I, alpha 1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DIO2 | deiodinase, iodothyronine, type II |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 |
| DMC1 | DNA meiotic recombinase 1 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DOCK5 | dedicator of cytokinesis 5 |
| DUSP21 | dual specificity phosphatase 21 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GJB5 | gap junction protein, beta 5, 31.1kDa |
| GPR135 | G protein-coupled receptor 135 |
| GPR27 | G protein-coupled receptor 27 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HIST1H2BL | histone cluster 1, H2bl |
| HIST1H2BN | histone cluster 1, H2bn |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| ICOS | inducible T-cell co-stimulator |
| IL36RN | interleukin 36 receptor antagonist |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KALRN | kalirin, RhoGEF kinase |
| KCNIP2 | Kv channel interacting protein 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIF17 | kinesin family member 17 |
| KLHL29 | kelch-like family member 29 |
| KLRC3 | killer cell lectin-like receptor subfamily C, member 3 |
| KRTAP2-4 | keratin associated protein 2-4 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MLN | motilin |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MON2 | MON2 homolog (S. cerevisiae) |
| MUC13 | mucin 13, cell surface associated |
| MUC3B | mucin 3B, cell surface associated |
| MVB12B | multivesicular body subunit 12B |
| MXD4 | MAX dimerization protein 4 |
| NMT2 | N-myristoyltransferase 2 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| PARVA | parvin, alpha |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PCDHA5 | protocadherin alpha 5 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PIWIL2 | piwi-like RNA-mediated gene silencing 2 |
| PLK3 | polo-like kinase 3 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| RAB3D | RAB3D, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RHCE | Rh blood group, CcEe antigens |
| RPL35A | ribosomal protein L35a |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SH3BP1 | SH3-domain binding protein 1 |
| SLAMF7 | SLAM family member 7 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SP1 | Sp1 transcription factor |
| SP140 | SP140 nuclear body protein |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SULF1 | sulfatase 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TBX1 | T-box 1 |
| TBX21 | T-box 21 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATG10 | autophagy related 10 |
| AURKC | aurora kinase C |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAX | BCL2-associated X protein |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBS | cystathionine-beta-synthase |
| CCDC134 | coiled-coil domain containing 134 |
| CCDC186 | coiled-coil domain containing 186 |
| CD34 | CD34 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CFAP69 | cilia and flagella associated protein 69 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHM | choroideremia (Rab escort protein 1) |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CPZ | carboxypeptidase Z |
| DOC2A | double C2-like domains, alpha |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DUSP9 | dual specificity phosphatase 9 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FGFR4 | fibroblast growth factor receptor 4 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GK3P | glycerol kinase 3 pseudogene |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR21 | G protein-coupled receptor 21 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HAL | histidine ammonia-lyase |
| HDAC7 | histone deacetylase 7 |
| HIST1H2AL | histone cluster 1, H2al |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXC11 | homeobox C11 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IL11RA | interleukin 11 receptor, alpha |
| IL12A | interleukin 12A |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KLHL36 | kelch-like family member 36 |
| KRT37 | keratin 37, type I |
| LINC00472 | long intergenic non-protein coding RNA 472 |
| LMTK2 | lemur tyrosine kinase 2 |
| LOC157562 | uncharacterized LOC157562 |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTA2 | metastasis associated 1 family, member 2 |
| NELL2 | NEL-like 2 (chicken) |
| NGF | nerve growth factor (beta polypeptide) |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NRSN2 | neurensin 2 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAQR5 | progestin and adipoQ receptor family member V |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PIP | prolactin-induced protein |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRR15L | proline rich 15-like |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RGCC | regulator of cell cycle |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLN | sarcolipin |
| STAB2 | stabilin 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBX19 | T-box 19 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TIMP4 | TIMP metallopeptidase inhibitor 4 |
| TPCN1 | two pore segment channel 1 |
| TRIM25 | tripartite motif containing 25 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TSPAN32 | tetraspanin 32 |
| TUBA4B | tubulin, alpha 4b |
| VGF | VGF nerve growth factor inducible |
| VLDLR | very low density lipoprotein receptor |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF334 | zinc finger protein 334 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF76 | zinc finger protein 76 |
| ZNF862 | zinc finger protein 862 |
