| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the mexiletine-3862 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AGFG2 | ArfGAP with FG repeats 2 |
| APOC1 | apolipoprotein C-I |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARTN | artemin |
| ASPN | asporin |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CBX2 | chromobox homolog 2 |
| CEP295 | centrosomal protein 295kDa |
| CNN1 | calponin 1, basic, smooth muscle |
| CNTFR | ciliary neurotrophic factor receptor |
| COL1A1 | collagen, type I, alpha 1 |
| COPA | coatomer protein complex, subunit alpha |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DAO | D-amino-acid oxidase |
| DAPK3 | death-associated protein kinase 3 |
| DICER1 | dicer 1, ribonuclease type III |
| DIO2 | deiodinase, iodothyronine, type II |
| DIXDC1 | DIX domain containing 1 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DSC2 | desmocollin 2 |
| DST | dystonin |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| EPB41L4A | erythrocyte membrane protein band 4.1 like 4A |
| ERCC2 | excision repair cross-complementation group 2 |
| ESR1 | estrogen receptor 1 |
| FAM120C | family with sequence similarity 120C |
| FKRP | fukutin related protein |
| FLOT1 | flotillin 1 |
| FN1 | fibronectin 1 |
| FOSL2 | FOS-like antigen 2 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR137 | G protein-coupled receptor 137 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSN | gelsolin |
| HFE | hemochromatosis |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HOXB5 | homeobox B5 |
| HTATSF1 | HIV-1 Tat specific factor 1 |
| IL17RC | interleukin 17 receptor C |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LMAN1 | lectin, mannose-binding, 1 |
| LOXL2 | lysyl oxidase-like 2 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MCL1 | myeloid cell leukemia 1 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| METTL7A | methyltransferase like 7A |
| MON2 | MON2 homolog (S. cerevisiae) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTMR8 | myotubularin related protein 8 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NOP16 | NOP16 nucleolar protein |
| PAPPA2 | pappalysin 2 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLCH1 | phospholipase C, eta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHH3 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 |
| PRKD1 | protein kinase D1 |
| PSAT1 | phosphoserine aminotransferase 1 |
| RB1 | retinoblastoma 1 |
| RCAN3 | RCAN family member 3 |
| RLN1 | relaxin 1 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RXRB | retinoid X receptor, beta |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIRT4 | sirtuin 4 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SP1 | Sp1 transcription factor |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TADA2A | transcriptional adaptor 2A |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TGM2 | transglutaminase 2 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM259 | transmembrane protein 259 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TYRO3 | TYRO3 protein tyrosine kinase |
| USP34 | ubiquitin specific peptidase 34 |
| WDR55 | WD repeat domain 55 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XCR1 | chemokine (C motif) receptor 1 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF324 | zinc finger protein 324 |
| ZNF384 | zinc finger protein 384 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADCY7 | adenylate cyclase 7 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AMH | anti-Mullerian hormone |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CCDC88C | coiled-coil domain containing 88C |
| CCDC9 | coiled-coil domain containing 9 |
| CD80 | CD80 molecule |
| CD8A | CD8a molecule |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLSPN | claspin |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CORO7 | coronin 7 |
| CRY2 | cryptochrome circadian clock 2 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CUL9 | cullin 9 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EFNA3 | ephrin-A3 |
| EMID1 | EMI domain containing 1 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| ERCC5 | excision repair cross-complementation group 5 |
| FAM76A | family with sequence similarity 76, member A |
| FGF4 | fibroblast growth factor 4 |
| FLJ22184 | |
| FOXN2 | forkhead box N2 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H1D | histone cluster 1, H1d |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IFNA14 | interferon, alpha 14 |
| IFT140 | intraflagellar transport 140 |
| IFT54 | intraflagellar transport 54 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KIAA1107 | KIAA1107 |
| LHX6 | LIM homeobox 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOXL3 | lysyl oxidase-like 3 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MFAP2 | microfibrillar-associated protein 2 |
| MTA2 | metastasis associated 1 family, member 2 |
| NEK11 | NIMA-related kinase 11 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPPA | natriuretic peptide A |
| NPTX1 | neuronal pentraxin I |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PITX1 | paired-like homeodomain 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLSCR4 | phospholipid scramblase 4 |
| PP14571 | uncharacterized LOC100130449 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB36 | RAB36, member RAS oncogene family |
| RAB40C | RAB40C, member RAS oncogene family |
| RGS19 | regulator of G-protein signaling 19 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF141 | ring finger protein 141 |
| RPL10L | ribosomal protein L10-like |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMIM14 | small integral membrane protein 14 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STON1 | stonin 1 |
| STRA6 | stimulated by retinoic acid 6 |
| TBC1D2 | TBC1 domain family, member 2 |
| TCP10 | t-complex 10 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRAIP | TRAF interacting protein |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSPYL2 | TSPY-like 2 |
| TUBA4B | tubulin, alpha 4b |
| TUBG2 | tubulin, gamma 2 |
| XAB2 | XPA binding protein 2 |
| YY2 | YY2 transcription factor |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF358 | zinc finger protein 358 |
| ZNF516 | zinc finger protein 516 |
| ZNF532 | zinc finger protein 532 |
| ZNF639 | zinc finger protein 639 |
| ZNF76 | zinc finger protein 76 |
