| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the mexiletine-3973 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVRL1 | activin A receptor type II-like 1 |
| AIM1L | absent in melanoma 1-like |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATP11A | ATPase, class VI, type 11A |
| ATXN3 | ataxin 3 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BGN | biglycan |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C6 | complement component 6 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALCR | calcitonin receptor |
| CCKAR | cholecystokinin A receptor |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDCP1 | CUB domain containing protein 1 |
| CHD2 | chromodomain helicase DNA binding protein 2 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLEC3B | C-type lectin domain family 3, member B |
| COL1A1 | collagen, type I, alpha 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DFNB31 | deafness, autosomal recessive 31 |
| DNAH9 | dynein, axonemal, heavy chain 9 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DOCK9 | dedicator of cytokinesis 9 |
| DPEP1 | dipeptidase 1 (renal) |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| FAM153A | family with sequence similarity 153, member A |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FRMD8 | FERM domain containing 8 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GPX7 | glutathione peroxidase 7 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GYPB | glycophorin B (MNS blood group) |
| HDAC7 | histone deacetylase 7 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HOXA1 | homeobox A1 |
| HOXB5 | homeobox B5 |
| HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IRF8 | interferon regulatory factor 8 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDR | kinase insert domain receptor |
| KLF12 | Kruppel-like factor 12 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LCT | lactase |
| LHX2 | LIM homeobox 2 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| MAP3K19 | mitogen-activated protein kinase kinase kinase 19 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MMP11 | matrix metallopeptidase 11 |
| NEUROD2 | neuronal differentiation 2 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NOV | nephroblastoma overexpressed |
| OBSL1 | obscurin-like 1 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PAX5 | paired box 5 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDE8B | phosphodiesterase 8B |
| PDZD2 | PDZ domain containing 2 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PML | promyelocytic leukemia |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRM1 | protamine 1 |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PTGDR2 | prostaglandin D2 receptor 2 |
| RBBP4 | retinoblastoma binding protein 4 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RHO | rhodopsin |
| RHOH | ras homolog family member H |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SAFB | scaffold attachment factor B |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC38A7 | solute carrier family 38, member 7 |
| SLC43A3 | solute carrier family 43, member 3 |
| SLC6A12 | solute carrier family 6 (neurotransmitter transporter), member 12 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| STAB1 | stabilin 1 |
| TCF20 | transcription factor 20 (AR1) |
| TPP1 | tripeptidyl peptidase I |
| TRADD | TNFRSF1A-associated via death domain |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XCR1 | chemokine (C motif) receptor 1 |
| ZNF234 | zinc finger protein 234 |
| ZNF3 | zinc finger protein 3 |
| ZNF335 | zinc finger protein 335 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| AHSP | alpha hemoglobin stabilizing protein |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BMP10 | bone morphogenetic protein 10 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CARTPT | CART prepropeptide |
| CD34 | CD34 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDK3 | cyclin-dependent kinase 3 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHKB | choline kinase beta |
| CHM | choroideremia (Rab escort protein 1) |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLDN1 | claudin 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| CNTFR | ciliary neurotrophic factor receptor |
| CTGF | connective tissue growth factor |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EFNB3 | ephrin-B3 |
| FAM120C | family with sequence similarity 120C |
| FAM171A1 | family with sequence similarity 171, member A1 |
| FBXO2 | F-box protein 2 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FER | fer (fps/fes related) tyrosine kinase |
| FLJ22184 | |
| GAS2 | growth arrest-specific 2 |
| GAST | gastrin |
| GK3P | glycerol kinase 3 pseudogene |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPR39 | G protein-coupled receptor 39 |
| GRPR | gastrin-releasing peptide receptor |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HDAC11 | histone deacetylase 11 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H4D | histone cluster 1, H4d |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITM2C | integral membrane protein 2C |
| JAM3 | junctional adhesion molecule 3 |
| KRT83 | keratin 83, type II |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LIF | leukemia inhibitory factor |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP2 | matrix metallopeptidase 2 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| MYLK | myosin light chain kinase |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NLRX1 | NLR family member X1 |
| NME5 | NME/NM23 family member 5 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCD1 | phospholipase C, delta 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| RAB3A | RAB3A, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RLN1 | relaxin 1 |
| RNF208 | ring finger protein 208 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCARA3 | scavenger receptor class A, member 3 |
| SDC3 | syndecan 3 |
| SETBP1 | SET binding protein 1 |
| SETD1A | SET domain containing 1A |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPAG4 | sperm associated antigen 4 |
| STX1A | syntaxin 1A (brain) |
| TH | tyrosine hydroxylase |
| TLR1 | toll-like receptor 1 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM120B | transmembrane protein 120B |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TRAF2 | TNF receptor-associated factor 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| VPS9D1 | VPS9 domain containing 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF343 | zinc finger protein 343 |
| ZNF862 | zinc finger protein 862 |
