| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the mexiletine-4338 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AADAC | arylacetamide deacetylase |
| AIM1L | absent in melanoma 1-like |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALB | albumin |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANGPTL4 | angiopoietin-like 4 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| CA14 | carbonic anhydrase XIV |
| CCDC132 | coiled-coil domain containing 132 |
| CD22 | CD22 molecule |
| CD34 | CD34 molecule |
| CDC14A | cell division cycle 14A |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLDN17 | claudin 17 |
| CLEC4E | C-type lectin domain family 4, member E |
| CLPS | colipase, pancreatic |
| CNTNAP2 | contactin associated protein-like 2 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CST4 | cystatin S |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| ERP44 | endoplasmic reticulum protein 44 |
| FOXF2 | forkhead box F2 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GH1 | growth hormone 1 |
| GP6 | glycoprotein VI (platelet) |
| GPR19 | G protein-coupled receptor 19 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| HFE | hemochromatosis |
| IHH | indian hedgehog |
| IL36G | interleukin 36, gamma |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KIF25 | kinesin family member 25 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KRT2 | keratin 2, type II |
| LAT2 | linker for activation of T cells family, member 2 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRC75B | leucine rich repeat containing 75B |
| MAGEA8 | melanoma antigen family A8 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MMP25 | matrix metallopeptidase 25 |
| MTA2 | metastasis associated 1 family, member 2 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NFASC | neurofascin |
| NPTX2 | neuronal pentraxin II |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PASK | PAS domain containing serine/threonine kinase |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLAC4 | placenta-specific 4 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRKCE | protein kinase C, epsilon |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PYY | peptide YY |
| RAB6B | RAB6B, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RANBP1 | RAN binding protein 1 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| REEP2 | receptor accessory protein 2 |
| RET | ret proto-oncogene |
| RFPL2 | ret finger protein-like 2 |
| RND1 | Rho family GTPase 1 |
| RNF122 | ring finger protein 122 |
| SCLY | selenocysteine lyase |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SIRT4 | sirtuin 4 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
| SNCAIP | synuclein, alpha interacting protein |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPP1 | secreted phosphoprotein 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAS2R4 | taste receptor, type 2, member 4 |
| TGM3 | transglutaminase 3 |
| TRIM14 | tripartite motif containing 14 |
| TSC22D2 | TSC22 domain family, member 2 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| Symbol | Name |
|---|---|
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1S | complement component 1, s subcomponent |
| C3 | complement component 3 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CASKIN2 | CASK interacting protein 2 |
| CCDC186 | coiled-coil domain containing 186 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CFAP69 | cilia and flagella associated protein 69 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CREB5 | cAMP responsive element binding protein 5 |
| CRY2 | cryptochrome circadian clock 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DEAF1 | DEAF1 transcription factor |
| DLL3 | delta-like 3 (Drosophila) |
| DOK5 | docking protein 5 |
| EPHA7 | EPH receptor A7 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM102A | family with sequence similarity 102, member A |
| FAM53C | family with sequence similarity 53, member C |
| FGF23 | fibroblast growth factor 23 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GLB1L | galactosidase, beta 1-like |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOMER2 | homer scaffolding protein 2 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IPO8 | importin 8 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KDM4D | lysine (K)-specific demethylase 4D |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MED15 | mediator complex subunit 15 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MID1IP1 | MID1 interacting protein 1 |
| MUC3B | mucin 3B, cell surface associated |
| NABP1 | nucleic acid binding protein 1 |
| NID2 | nidogen 2 (osteonidogen) |
| NKX3-2 | NK3 homeobox 2 |
| NME5 | NME/NM23 family member 5 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OSMR | oncostatin M receptor |
| PENK | proenkephalin |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POLL | polymerase (DNA directed), lambda |
| POMT2 | protein-O-mannosyltransferase 2 |
| PTK6 | protein tyrosine kinase 6 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB5B | RAB5B, member RAS oncogene family |
| SCIN | scinderin |
| SETD1A | SET domain containing 1A |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SOD3 | superoxide dismutase 3, extracellular |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STAB2 | stabilin 2 |
| STON1 | stonin 1 |
| STRA6 | stimulated by retinoic acid 6 |
| STRN4 | striatin, calmodulin binding protein 4 |
| TEP1 | telomerase-associated protein 1 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TLN1 | talin 1 |
| TMEM209 | transmembrane protein 209 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TPCN1 | two pore segment channel 1 |
| TTN | titin |
| UNKL | unkempt family zinc finger-like |
| USP20 | ubiquitin specific peptidase 20 |
| WDR25 | WD repeat domain 25 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF219 | zinc finger protein 219 |
| ZNF492 | zinc finger protein 492 |
| ZNF652 | zinc finger protein 652 |
| ZNF711 | zinc finger protein 711 |
| ZNF76 | zinc finger protein 76 |
| ZNF768 | zinc finger protein 768 |
