mhc class i peptide loading complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules. (Gene Ontology, GO_0042824)
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Genes

38 proteins co-occuring with the mhc class i peptide loading complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
HLA-B major histocompatibility complex, class I, B 2.01124
TAPBP TAP binding protein (tapasin) 1.9969
CALR calreticulin 1.12909
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.10919
HLA-A major histocompatibility complex, class I, A 1.08069
B2M beta-2-microglobulin 1.07765
HLA-E major histocompatibility complex, class I, E 1.02281
CLP1 cleavage and polyadenylation factor I subunit 1 0.782326
HLA-C major histocompatibility complex, class I, C 0.766804
TAPBPL TAP binding protein-like 0.716791
CANX calnexin 0.674196
PDIA3 protein disulfide isomerase family A, member 3 0.52716
PBX2 pre-B-cell leukemia homeobox 2 0.517348
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.515308
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.499853
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.464397
WRB tryptophan rich basic protein 0.461199
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.441708
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 0.421997
PURB purine-rich element binding protein B 0.386979
HEPH hephaestin 0.363949
CD4 CD4 molecule 0.357847
NXT1 nuclear transport factor 2-like export factor 1 0.344935
NPAS4 neuronal PAS domain protein 4 0.305515
SEC23B Sec23 homolog B (S. cerevisiae) 0.284769
TPP2 tripeptidyl peptidase II 0.274101
PCDH8 protocadherin 8 0.257289
KCNT1 potassium channel, sodium activated subfamily T, member 1 0.250026
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.24713
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 0.237042
IRF1 interferon regulatory factor 1 0.233101
IRF2 interferon regulatory factor 2 0.218212
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 0.217861
SFN stratifin 0.1921
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 0.187333
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.181823
C1R complement component 1, r subcomponent 0.173543
HYOU1 hypoxia up-regulated 1 0.157039
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