mianserin-1385 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the mianserin-1385 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKRD12 ankyrin repeat domain 12
ANXA11 annexin A11
ARID4A AT rich interactive domain 4A (RBP1-like)
BTN3A2 butyrophilin, subfamily 3, member A2
C12ORF29 chromosome 12 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CBX5 chromobox homolog 5
CBX6 chromobox homolog 6
CCNA1 cyclin A1
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDK3 cyclin-dependent kinase 3
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEP63 centrosomal protein 63kDa
CUL5 cullin 5
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DOLK dolichol kinase
DPYSL2 dihydropyrimidinase-like 2
DSCR3 Down syndrome critical region 3
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
E2F4 E2F transcription factor 4, p107/p130-binding
ECE1 endothelin converting enzyme 1
EGR2 early growth response 2
EGR3 early growth response 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHB3 EPH receptor B3
F11R F11 receptor
FASTK Fas-activated serine/threonine kinase
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FLJ10038 uncharacterized protein FLJ10038
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GPSM3 G-protein signaling modulator 3
GUSBP3 glucuronidase, beta pseudogene 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H4J histone cluster 1, H4j
HOMER1 homer scaffolding protein 1
ICAM1 intercellular adhesion molecule 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
INTS1 integrator complex subunit 1
KDM2A lysine (K)-specific demethylase 2A
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LMO4 LIM domain only 4
LPP LIM domain containing preferred translocation partner in lipoma
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGT1 magnesium transporter 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBD1 methyl-CpG binding domain protein 1
MBOAT7 membrane bound O-acyltransferase domain containing 7
MED18 mediator complex subunit 18
MMP19 matrix metallopeptidase 19
MPPE1 metallophosphoesterase 1
MSH3 mutS homolog 3
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFX1 nuclear transcription factor, X-box binding 1
NMT1 N-myristoyltransferase 1
ODF2 outer dense fiber of sperm tails 2
PAQR6 progestin and adipoQ receptor family member VI
PCM1 pericentriolar material 1
PCNX pecanex homolog (Drosophila)
PECAM1 platelet/endothelial cell adhesion molecule 1
PIAS4 protein inhibitor of activated STAT, 4
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLEKHO1 pleckstrin homology domain containing, family O member 1
PNOC prepronociceptin
PNPLA4 patatin-like phospholipase domain containing 4
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PRRC1 proline-rich coiled-coil 1
PRRC2C proline-rich coiled-coil 2C
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RANBP10 RAN binding protein 10
RNF31 ring finger protein 31
RPL37A ribosomal protein L37a
SCAMP1 secretory carrier membrane protein 1
SEC23IP SEC23 interacting protein
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SGK1 serum/glucocorticoid regulated kinase 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
STK19 serine/threonine kinase 19
TBL1X transducin (beta)-like 1X-linked
TCAF1 TRPM8 channel-associated factor 1
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TFCP2L1 transcription factor CP2-like 1
TGIF2 TGFB-induced factor homeobox 2
TMED1 transmembrane emp24 protein transport domain containing 1
TRA T cell receptor alpha locus
TULP3 tubby like protein 3
UBE2O ubiquitin-conjugating enzyme E2O
URI1 URI1, prefoldin-like chaperone
USF2 upstream transcription factor 2, c-fos interacting
YIPF6 Yip1 domain family, member 6
ZNF337 zinc finger protein 337
ZNF444 zinc finger protein 444
ZNF552 zinc finger protein 552
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACVR1 activin A receptor, type I
ACVR2A activin A receptor, type IIA
ADAM15 ADAM metallopeptidase domain 15
APOC4 apolipoprotein C-IV
B3GNT1
BTNL3 butyrophilin-like 3
CCDC176 coiled-coil domain containing 176
CD151 CD151 molecule (Raph blood group)
CD82 CD82 molecule
CENPQ centromere protein Q
CEP70 centrosomal protein 70kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLDN11 claudin 11
COQ4 coenzyme Q4
CTSG cathepsin G
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DENND4A DENN/MADD domain containing 4A
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DIXDC1 DIX domain containing 1
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
ERCC6 excision repair cross-complementation group 6
ERO1L ERO1-like (S. cerevisiae)
FAF1 Fas (TNFRSF6) associated factor 1
FAM172A family with sequence similarity 172, member A
GDF9 growth differentiation factor 9
GIMAP6 GTPase, IMAP family member 6
GMEB1 glucocorticoid modulatory element binding protein 1
GPKOW G patch domain and KOW motifs
GPR27 G protein-coupled receptor 27
GRM6 glutamate receptor, metabotropic 6
GSTA4 glutathione S-transferase alpha 4
GTF2IRD1 GTF2I repeat domain containing 1
HDAC4 histone deacetylase 4
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HYAL2 hyaluronoglucosaminidase 2
IL2RB interleukin 2 receptor, beta
ILK integrin-linked kinase
IMPAD1 inositol monophosphatase domain containing 1
IRAK4 interleukin-1 receptor-associated kinase 4
IRF9 interferon regulatory factor 9
KCTD20 potassium channel tetramerization domain containing 20
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAGOHB mago-nashi homolog B (Drosophila)
METRN meteorin, glial cell differentiation regulator
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MLYCD malonyl-CoA decarboxylase
MNS1 meiosis-specific nuclear structural 1
MTERF4 mitochondrial transcription termination factor 4
MX2 MX dynamin-like GTPase 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1H2 nuclear receptor subfamily 1, group H, member 2
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX26 peroxisomal biogenesis factor 26
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PSRC1 proline/serine-rich coiled-coil 1
PTGES2 prostaglandin E synthase 2
RBM15B RNA binding motif protein 15B
RBM38 RNA binding motif protein 38
RBM47 RNA binding motif protein 47
RBMS3 RNA binding motif, single stranded interacting protein 3
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPAP1 RNA polymerase II associated protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RWDD3 RWD domain containing 3
SARS2 seryl-tRNA synthetase 2, mitochondrial
SETMAR SET domain and mariner transposase fusion gene
SIRT6 sirtuin 6
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SNAP29 synaptosomal-associated protein, 29kDa
SPC25 SPC25, NDC80 kinetochore complex component
SPI1 Spi-1 proto-oncogene
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPX spexin hormone
STAC SH3 and cysteine rich domain
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTN2 tectonic family member 2
TEX40 testis expressed 40
TGFB3 transforming growth factor, beta 3
TMEM243 transmembrane protein 243, mitochondrial
TRAPPC11 trafficking protein particle complex 11
TTC13 tetratricopeptide repeat domain 13
TUBA3D tubulin, alpha 3d
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBIAD1 UbiA prenyltransferase domain containing 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
ZIM2 zinc finger, imprinted 2
ZNF189 zinc finger protein 189
ZNF226 zinc finger protein 226
ZNF408 zinc finger protein 408
ZNF8 zinc finger protein 8