mianserin-2068 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the mianserin-2068 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARSB arylsulfatase B
BCL2L1 BCL2-like 1
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BTG2 BTG family, member 2
BTN3A1 butyrophilin, subfamily 3, member A1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CCNG2 cyclin G2
CENPO centromere protein O
CHM choroideremia (Rab escort protein 1)
CLTB clathrin, light chain B
COL6A1 collagen, type VI, alpha 1
COPA coatomer protein complex, subunit alpha
CREB1 cAMP responsive element binding protein 1
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DENND4A DENN/MADD domain containing 4A
EHD1 EH-domain containing 1
EIF5A eukaryotic translation initiation factor 5A
EN1 engrailed homeobox 1
ENDOD1 endonuclease domain containing 1
FCF1 FCF1 rRNA-processing protein
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GSK3A glycogen synthase kinase 3 alpha
GULP1 GULP, engulfment adaptor PTB domain containing 1
HOXC8 homeobox C8
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ING4 inhibitor of growth family, member 4
KRT17 keratin 17, type I
LIMD1 LIM domains containing 1
LINC00094 long intergenic non-protein coding RNA 94
LMAN1 lectin, mannose-binding, 1
MAP4 microtubule-associated protein 4
MBNL2 muscleblind-like splicing regulator 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCL1 myeloid cell leukemia 1
MED28 mediator complex subunit 28
MEF2C myocyte enhancer factor 2C
MET MET proto-oncogene, receptor tyrosine kinase
MTAP methylthioadenosine phosphorylase
MTMR2 myotubularin related protein 2
MTUS1 microtubule associated tumor suppressor 1
MYH14 myosin, heavy chain 14, non-muscle
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OLFML2A olfactomedin-like 2A
OSMR oncostatin M receptor
PAPOLA poly(A) polymerase alpha
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PGAP1 post-GPI attachment to proteins 1
PICALM phosphatidylinositol binding clathrin assembly protein
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP5C protein phosphatase 5, catalytic subunit
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PSD3 pleckstrin and Sec7 domain containing 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
QKI QKI, KH domain containing, RNA binding
RANBP1 RAN binding protein 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RNASEH2B ribonuclease H2, subunit B
RNF6 ring finger protein (C3H2C3 type) 6
SCAMP1 secretory carrier membrane protein 1
SCARB2 scavenger receptor class B, member 2
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SENP7 SUMO1/sentrin specific peptidase 7
SLC25A44 solute carrier family 25, member 44
SMAD5 SMAD family member 5
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC5 structural maintenance of chromosomes 5
SNAP23 synaptosomal-associated protein, 23kDa
SOS2 son of sevenless homolog 2 (Drosophila)
SP110 SP110 nuclear body protein
SS18 synovial sarcoma translocation, chromosome 18
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STX16 syntaxin 16
SUGP1 SURP and G patch domain containing 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAOK3 TAO kinase 3
TM2D1 TM2 domain containing 1
TMEM159 transmembrane protein 159
TRAF4 TNF receptor-associated factor 4
TXNIP thioredoxin interacting protein
UGT8 UDP glycosyltransferase 8
ULBP2 UL16 binding protein 2
VGLL3 vestigial-like family member 3
WDFY3 WD repeat and FYVE domain containing 3
WDR1 WD repeat domain 1

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASB13 ankyrin repeat and SOCS box containing 13
ATP10D ATPase, class V, type 10D
AVEN apoptosis, caspase activation inhibitor
AXIN1 axin 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BDNF brain-derived neurotrophic factor
BMP15 bone morphogenetic protein 15
C1ORF115 chromosome 1 open reading frame 115
CAMK1 calcium/calmodulin-dependent protein kinase I
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCNF cyclin F
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPQ centromere protein Q
CEP131 centrosomal protein 131kDa
CEP85 centrosomal protein 85kDa
CLCN5 chloride channel, voltage-sensitive 5
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFCAB2 EF-hand calcium binding domain 2
ELOVL4 ELOVL fatty acid elongase 4
FAM127B family with sequence similarity 127, member B
FAM155A family with sequence similarity 155, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FURIN furin (paired basic amino acid cleaving enzyme)
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GLDC glycine dehydrogenase (decarboxylating)
GNL1 guanine nucleotide binding protein-like 1
GRWD1 glutamate-rich WD repeat containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HDAC5 histone deacetylase 5
HPS6 Hermansky-Pudlak syndrome 6
IGFLR1 IGF-like family receptor 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF9 interferon regulatory factor 9
KDM5C lysine (K)-specific demethylase 5C
KPTN kaptin (actin binding protein)
KRT15 keratin 15, type I
KRT86 keratin 86, type II
L2HGDH L-2-hydroxyglutarate dehydrogenase
MAP9 microtubule-associated protein 9
MATN3 matrilin 3
MBD5 methyl-CpG binding domain protein 5
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MED22 mediator complex subunit 22
MFGE8 milk fat globule-EGF factor 8 protein
MMP13 matrix metallopeptidase 13
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDRG4 NDRG family member 4
NOL12 nucleolar protein 12
NRGN neurogranin (protein kinase C substrate, RC3)
NUBP2 nucleotide binding protein 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
PAQR4 progestin and adipoQ receptor family member IV
PARP16 poly (ADP-ribose) polymerase family, member 16
PC pyruvate carboxylase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
POMT1 protein-O-mannosyltransferase 1
POMT2 protein-O-mannosyltransferase 2
POTEKP POTE ankyrin domain family, member K, pseudogene
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SDC3 syndecan 3
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SECISBP2 SECIS binding protein 2
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPEG SPEG complex locus
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST5 suppression of tumorigenicity 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCTN1 tectonic family member 1
TDRD3 tudor domain containing 3
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TOR3A torsin family 3, member A
TRMT61A tRNA methyltransferase 61A
TSKU tsukushi, small leucine rich proteoglycan
USP18 ubiquitin specific peptidase 18
WNT7A wingless-type MMTV integration site family, member 7A
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB48 zinc finger and BTB domain containing 48
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF574 zinc finger protein 574
ZNF767P zinc finger family member 767, pseudogene
ZNF862 zinc finger protein 862