mianserin-2231 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the mianserin-2231 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRB2 adhesion G protein-coupled receptor B2
AHNAK AHNAK nucleoprotein
AIF1 allograft inflammatory factor 1
AK2 adenylate kinase 2
ALMS1 Alstrom syndrome protein 1
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C19ORF66 chromosome 19 open reading frame 66
C21ORF2 chromosome 21 open reading frame 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD48 CD48 molecule
CDC42 cell division cycle 42
CFAP70 cilia and flagella associated protein 70
CFDP1 craniofacial development protein 1
CFLAR CASP8 and FADD-like apoptosis regulator
CFP complement factor properdin
COL13A1 collagen, type XIII, alpha 1
CTBP2 C-terminal binding protein 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLC1 DLC1 Rho GTPase activating protein
DMPK dystrophia myotonica-protein kinase
DOCK5 dedicator of cytokinesis 5
ECE1 endothelin converting enzyme 1
EFNB3 ephrin-B3
ELOVL5 ELOVL fatty acid elongase 5
ERCC4 excision repair cross-complementation group 4
ETV6 ets variant 6
FAM186A family with sequence similarity 186, member A
FN1 fibronectin 1
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GUSBP3 glucuronidase, beta pseudogene 3
HBEGF heparin-binding EGF-like growth factor
HFE hemochromatosis
HOXA10 homeobox A10
IL6ST interleukin 6 signal transducer
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
ITM2C integral membrane protein 2C
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF25-AS1 KIF25 antisense RNA 1
LOXL2 lysyl oxidase-like 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBD2 methyl-CpG binding domain protein 2
MED18 mediator complex subunit 18
MEX3D mex-3 RNA binding family member D
MFSD6 major facilitator superfamily domain containing 6
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NF2 neurofibromin 2 (merlin)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NGLY1 N-glycanase 1
NME5 NME/NM23 family member 5
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A3 nuclear receptor subfamily 4, group A, member 3
PALM paralemmin
PAQR5 progestin and adipoQ receptor family member V
PARD6B par-6 family cell polarity regulator beta
PAX5 paired box 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
POFUT2 protein O-fucosyltransferase 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSCA prostate stem cell antigen
PSG6 pregnancy specific beta-1-glycoprotein 6
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTAFR platelet-activating factor receptor
RABGAP1 RAB GTPase activating protein 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RB1 retinoblastoma 1
RBM12B RNA binding motif protein 12B
RBM5 RNA binding motif protein 5
RHOBTB2 Rho-related BTB domain containing 2
RNGTT RNA guanylyltransferase and 5'-phosphatase
SH2D3A SH2 domain containing 3A
SIGLEC6 sialic acid binding Ig-like lectin 6
SKIL SKI-like proto-oncogene
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SPRR1B small proline-rich protein 1B
SRSF5 serine/arginine-rich splicing factor 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TAS2R1 taste receptor, type 2, member 1
TBKBP1 TBK1 binding protein 1
TGFB2 transforming growth factor, beta 2
TGFBR3 transforming growth factor, beta receptor III
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
WIPI2 WD repeat domain, phosphoinositide interacting 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZMYND8 zinc finger, MYND-type containing 8
ZNF235 zinc finger protein 235
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMPD1 adenosine monophosphate deaminase 1
APOLD1 apolipoprotein L domain containing 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARMCX2 armadillo repeat containing, X-linked 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C14ORF93 chromosome 14 open reading frame 93
C17ORF53 chromosome 17 open reading frame 53
C2ORF27A chromosome 2 open reading frame 27A
C5 complement component 5
CA11 carbonic anhydrase XI
CA5BP1 carbonic anhydrase VB pseudogene 1
CD3D CD3d molecule, delta (CD3-TCR complex)
CDH10 cadherin 10, type 2 (T2-cadherin)
CDON cell adhesion associated, oncogene regulated
CEL carboxyl ester lipase
CEP85 centrosomal protein 85kDa
CHST10 carbohydrate sulfotransferase 10
CIC capicua transcriptional repressor
CORT cortistatin
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DGAT1 diacylglycerol O-acyltransferase 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DPY19L1P1 DPY19L1 pseudogene 1
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELSPBP1 epididymal sperm binding protein 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETAA1 Ewing tumor-associated antigen 1
ETNK2 ethanolamine kinase 2
FBXL8 F-box and leucine-rich repeat protein 8
FLJ11710 uncharacterized protein FLJ11710
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GJA9 gap junction protein, alpha 9, 59kDa
GLRA1 glycine receptor, alpha 1
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSTM5 glutathione S-transferase mu 5
HIST1H3B histone cluster 1, H3b
IFT54 intraflagellar transport 54
KLHL36 kelch-like family member 36
KLK5 kallikrein-related peptidase 5
KREMEN2 kringle containing transmembrane protein 2
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCOLN1 mucolipin 1
MGC12488
MON1B MON1 secretory trafficking family member B
MORC3 MORC family CW-type zinc finger 3
MSI1 musashi RNA-binding protein 1
MVP major vault protein
NEUROD4 neuronal differentiation 4
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NPM3 nucleophosmin/nucleoplasmin 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAIP2B poly(A) binding protein interacting protein 2B
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITX2 paired-like homeodomain 2
PLAC1 placenta-specific 1
POLL polymerase (DNA directed), lambda
POLM polymerase (DNA directed), mu
PTPRS protein tyrosine phosphatase, receptor type, S
RAB5C RAB5C, member RAS oncogene family
RCAN3 RCAN family member 3
RECQL4 RecQ protein-like 4
SAYSD1 SAYSVFN motif domain containing 1
SEC14L5 SEC14-like 5 (S. cerevisiae)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH2D4A SH2 domain containing 4A
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC44A1 solute carrier family 44 (choline transporter), member 1
SOX3 SRY (sex determining region Y)-box 3
STAB2 stabilin 2
STIM1 stromal interaction molecule 1
SYNC syncoilin, intermediate filament protein
TBC1D17 TBC1 domain family, member 17
TBX19 T-box 19
TESC tescalcin
TICAM1 toll-like receptor adaptor molecule 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM45A transmembrane protein 45A
TPCN1 two pore segment channel 1
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN2 tetraspanin 2
UNC119 unc-119 homolog (C. elegans)
ZNF204P zinc finger protein 204, pseudogene
ZNF205 zinc finger protein 205
ZNF37BP zinc finger protein 37B, pseudogene
ZNF747 zinc finger protein 747
ZNF804A zinc finger protein 804A