mianserin-5786 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the mianserin-5786 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADORA3 adenosine A3 receptor
ALOX5 arachidonate 5-lipoxygenase
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ARC activity-regulated cytoskeleton-associated protein
ASIC1 acid sensing (proton gated) ion channel 1
ATF3 activating transcription factor 3
BIRC3 baculoviral IAP repeat containing 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C8ORF60 chromosome 8 open reading frame 60
CCNO cyclin O
CDC14A cell division cycle 14A
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLDN1 claudin 1
CTBP2 C-terminal binding protein 2
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT3 DNA-damage-inducible transcript 3
DENND3 DENN/MADD domain containing 3
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUSP2 dual specificity phosphatase 2
EGR1 early growth response 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV6 ets variant 6
FGF5 fibroblast growth factor 5
GPRC5B G protein-coupled receptor, class C, group 5, member B
GSTM5 glutathione S-transferase mu 5
HDAC9 histone deacetylase 9
ICAM1 intercellular adhesion molecule 1
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
IFFO1 intermediate filament family orphan 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL6 interleukin 6
IL7R interleukin 7 receptor
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCTD17 potassium channel tetramerization domain containing 17
KIAA1644 KIAA1644
KRT34 keratin 34, type I
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LRRN3 leucine rich repeat neuronal 3
MAP3K7CL MAP3K7 C-terminal like
MFAP3 microfibrillar-associated protein 3
MPZ myelin protein zero
MYO9B myosin IXB
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NAV3 neuron navigator 3
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
OGFR opioid growth factor receptor
OPRL1 opiate receptor-like 1
ORC5 origin recognition complex, subunit 5
PCDH7 protocadherin 7
PCSK6 proprotein convertase subtilisin/kexin type 6
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX2 PBX/knotted 1 homeobox 2
PLBD1 phospholipase B domain containing 1
PRLH prolactin releasing hormone
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRR protein tyrosine phosphatase, receptor type, R
PVR poliovirus receptor
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RGS4 regulator of G-protein signaling 4
RNF185 ring finger protein 185
RPS14 ribosomal protein S14
RTEL1 regulator of telomere elongation helicase 1
S1PR1 sphingosine-1-phosphate receptor 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SYNDIG1 synapse differentiation inducing 1
TGFB2 transforming growth factor, beta 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMOD1 tropomodulin 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TYMS thymidylate synthetase
UGCG UDP-glucose ceramide glucosyltransferase
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
XYLB xylulokinase homolog (H. influenzae)
ZC2HC1C zinc finger, C2HC-type containing 1C
ZC3H13 zinc finger CCCH-type containing 13
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF224 zinc finger protein 224

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARHGAP24 Rho GTPase activating protein 24
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASB13 ankyrin repeat and SOCS box containing 13
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BEND5 BEN domain containing 5
BMP15 bone morphogenetic protein 15
C17ORF53 chromosome 17 open reading frame 53
C1RL complement component 1, r subcomponent-like
CDKL3 cyclin-dependent kinase-like 3
CEMIP cell migration inducing protein, hyaluronan binding
CFAP44 cilia and flagella associated protein 44
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLEC2B C-type lectin domain family 2, member B
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CSF1R colony stimulating factor 1 receptor
CTC1 CTS telomere maintenance complex component 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DNAH7 dynein, axonemal, heavy chain 7
DNAL4 dynein, axonemal, light chain 4
DPY19L2P2 DPY19L2 pseudogene 2
EN1 engrailed homeobox 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM222B family with sequence similarity 222, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FRS3 fibroblast growth factor receptor substrate 3
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLS2 glutaminase 2 (liver, mitochondrial)
GMIP GEM interacting protein
GPR19 G protein-coupled receptor 19
HDAC5 histone deacetylase 5
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HIST1H4D histone cluster 1, H4d
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IDI2-AS1 IDI2 antisense RNA 1
IL2 interleukin 2
IL4R interleukin 4 receptor
ISYNA1 inositol-3-phosphate synthase 1
ITGA10 integrin, alpha 10
JAM3 junctional adhesion molecule 3
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0513 KIAA0513
KRT75 keratin 75, type II
KRT86 keratin 86, type II
KRT9 keratin 9, type I
LINS lines homolog (Drosophila)
LMO7 LIM domain 7
LOC729164 hCG1732469
LRP3 low density lipoprotein receptor-related protein 3
LYPD3 LY6/PLAUR domain containing 3
MANBA mannosidase, beta A, lysosomal
MAST3 microtubule associated serine/threonine kinase 3
MVP major vault protein
MYO1F myosin IF
NKX3-2 NK3 homeobox 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PAQR6 progestin and adipoQ receptor family member VI
PCOLCE procollagen C-endopeptidase enhancer
PDE12 phosphodiesterase 12
PODXL2 podocalyxin-like 2
QSER1 glutamine and serine rich 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RNF2 ring finger protein 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SDC3 syndecan 3
SLC46A3 solute carrier family 46, member 3
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SPIDR scaffolding protein involved in DNA repair
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STARD3 StAR-related lipid transfer (START) domain containing 3
TENM4 teneurin transmembrane protein 4
TEX40 testis expressed 40
TMC7 transmembrane channel-like 7
TMEM104 transmembrane protein 104
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRIM66 tripartite motif containing 66
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UGT8 UDP glycosyltransferase 8
USB1 U6 snRNA biogenesis 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZMAT5 zinc finger, matrin-type 5
ZNF137P zinc finger protein 137, pseudogene
ZNF204P zinc finger protein 204, pseudogene
ZNF205 zinc finger protein 205
ZNF230 zinc finger protein 230
ZNF350 zinc finger protein 350