miconazole-1977 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the miconazole-1977 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADK adenosine kinase
AGGF1 angiogenic factor with G patch and FHA domains 1
AK1 adenylate kinase 1
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGAP4 Rho GTPase activating protein 4
ATAT1 alpha tubulin acetyltransferase 1
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BBX bobby sox homolog (Drosophila)
BRAP BRCA1 associated protein
C16ORF58 chromosome 16 open reading frame 58
C2ORF27A chromosome 2 open reading frame 27A
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEP170 centrosomal protein 170kDa
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLCN7 chloride channel, voltage-sensitive 7
CLIC4 chloride intracellular channel 4
CLIC5 chloride intracellular channel 5
CREBZF CREB/ATF bZIP transcription factor
CREM cAMP responsive element modulator
CS citrate synthase
DNASE1L1 deoxyribonuclease I-like 1
DPY19L1 dpy-19-like 1 (C. elegans)
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EPS15 epidermal growth factor receptor pathway substrate 15
ETV5 ets variant 5
FBXO31 F-box protein 31
FBXO42 F-box protein 42
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GK glycerol kinase
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
HBS1L HBS1-like translational GTPase
HIST1H4J histone cluster 1, H4j
HTT huntingtin
IL13RA1 interleukin 13 receptor, alpha 1
JAG1 jagged 1
KIFAP3 kinesin-associated protein 3
KLHL18 kelch-like family member 18
KLHL7 kelch-like family member 7
KPNA1 karyopherin alpha 1 (importin alpha 5)
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LZTFL1 leucine zipper transcription factor-like 1
MAP2K2 mitogen-activated protein kinase kinase 2
MBIP MAP3K12 binding inhibitory protein 1
MECP2 methyl CpG binding protein 2
METTL7A methyltransferase like 7A
MPDU1 mannose-P-dolichol utilization defect 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFYA nuclear transcription factor Y, alpha
NOP16 NOP16 nucleolar protein
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUP98 nucleoporin 98kDa
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OVGP1 oviductal glycoprotein 1, 120kDa
P4HB prolyl 4-hydroxylase, beta polypeptide
PARP16 poly (ADP-ribose) polymerase family, member 16
PFDN4 prefoldin subunit 4
PIBF1 progesterone immunomodulatory binding factor 1
PIDD1 p53-induced death domain protein 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLCD1 phospholipase C, delta 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POR P450 (cytochrome) oxidoreductase
PPAP2A phosphatidic acid phosphatase type 2A
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAD17 RAD17 homolog (S. pombe)
RAP1GAP RAP1 GTPase activating protein
RB1 retinoblastoma 1
RBM19 RNA binding motif protein 19
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RNF2 ring finger protein 2
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
SAFB2 scaffold attachment factor B2
SAG S-antigen; retina and pineal gland (arrestin)
SCAMP1 secretory carrier membrane protein 1
SEC31A SEC31 homolog A (S. cerevisiae)
SECISBP2L SECIS binding protein 2-like
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMO smoothened, frizzled class receptor
SPDEF SAM pointed domain containing ETS transcription factor
STK19 serine/threonine kinase 19
SUGP2 SURP and G patch domain containing 2
TBCE tubulin folding cofactor E
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMPO thymopoietin
TRD T cell receptor delta locus
TSFM Ts translation elongation factor, mitochondrial
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTLL4 tubulin tyrosine ligase-like family member 4
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
YIPF4 Yip1 domain family, member 4
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZNF335 zinc finger protein 335

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACSL5 acyl-CoA synthetase long-chain family member 5
ADGRE5 adhesion G protein-coupled receptor E5
ADM adrenomedullin
ANKRD11 ankyrin repeat domain 11
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APH1B APH1B gamma secretase subunit
ASB13 ankyrin repeat and SOCS box containing 13
ATF3 activating transcription factor 3
ATXN2 ataxin 2
BCL7B B-cell CLL/lymphoma 7B
C11ORF68 chromosome 11 open reading frame 68
C3 complement component 3
C6ORF47 chromosome 6 open reading frame 47
CBR1 carbonyl reductase 1
CD151 CD151 molecule (Raph blood group)
CD302 CD302 molecule
CD83 CD83 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COMMD10 COMM domain containing 10
COPS7B COP9 signalosome subunit 7B
COQ4 coenzyme Q4
CXCL8 chemokine (C-X-C motif) ligand 8
DAO D-amino-acid oxidase
DCPS decapping enzyme, scavenger
DDIT4 DNA-damage-inducible transcript 4
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DENND5A DENN/MADD domain containing 5A
DHDDS dehydrodolichyl diphosphate synthase
DPH2 DPH2 homolog (S. cerevisiae)
DRAM1 DNA-damage regulated autophagy modulator 1
ELP4 elongator acetyltransferase complex subunit 4
EXD2 exonuclease 3'-5' domain containing 2
EXOSC9 exosome component 9
FAM222B family with sequence similarity 222, member B
FANCE Fanconi anemia, complementation group E
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GOLGA3 golgin A3
GOLPH3L golgi phosphoprotein 3-like
GORASP1 golgi reassembly stacking protein 1, 65kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HP haptoglobin
IER3 immediate early response 3
IL2RG interleukin 2 receptor, gamma
ILK integrin-linked kinase
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INO80D INO80 complex subunit D
INPPL1 inositol polyphosphate phosphatase-like 1
KCTD20 potassium channel tetramerization domain containing 20
KIAA0753 KIAA0753
KLF10 Kruppel-like factor 10
KRI1 KRI1 homolog (S. cerevisiae)
LOC642236 FSHD region gene 1 pseudogene
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRP3 low density lipoprotein receptor-related protein 3
MAPK3 mitogen-activated protein kinase 3
MED15 mediator complex subunit 15
MED22 mediator complex subunit 22
MNAT1 MNAT CDK-activating kinase assembly factor 1
MX2 MX dynamin-like GTPase 2
MYLIP myosin regulatory light chain interacting protein
NCF1C neutrophil cytosolic factor 1C pseudogene
NOTCH1 notch 1
NUBP2 nucleotide binding protein 2
OCEL1 occludin/ELL domain containing 1
PAK1IP1 PAK1 interacting protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PMM1 phosphomannomutase 1
RAD54L RAD54-like (S. cerevisiae)
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RRAGA Ras-related GTP binding A
SCN10A sodium channel, voltage gated, type X alpha subunit
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SFMBT1 Scm-like with four mbt domains 1
SNX15 sorting nexin 15
SP140L SP140 nuclear body protein-like
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STEAP3 STEAP family member 3, metalloreductase
STRA13 stimulated by retinoic acid 13
TDP1 tyrosyl-DNA phosphodiesterase 1
TEX30 testis expressed 30
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM127 transmembrane protein 127
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
TRIM8 tripartite motif containing 8
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
VASP vasodilator-stimulated phosphoprotein
WNT10B wingless-type MMTV integration site family, member 10B
ZNF654 zinc finger protein 654