microcephaly Gene Set

Dataset IMPC Knockout Mouse Phenotypes
Category disease or phenotype associations
Type phenotype
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_10907)
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Genes

34 gene knockouts causing the microcephaly phenotype in mic from the IMPC Knockout Mouse Phenotypes dataset.

Symbol Name
ACTG1 actin gamma 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
CEP97 centrosomal protein 97kDa
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CWC22 CWC22 spliceosome-associated protein
DBN1 drebrin 1
DLG5 discs, large homolog 5 (Drosophila)
DNM1 dynamin 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GJB3 gap junction protein, beta 3, 31kDa
KRT14 keratin 14, type I
LGI4 leucine-rich repeat LGI family, member 4
MBD6 methyl-CpG binding domain protein 6
MYB v-myb avian myeloblastosis viral oncogene homolog
NALCN sodium leak channel, non selective
NXN nucleoredoxin
PCCB propionyl CoA carboxylase, beta polypeptide
RBBP4 retinoblastoma binding protein 4
RBM22 RNA binding motif protein 22
RNF10 ring finger protein 10
SCX scleraxis basic helix-loop-helix transcription factor
SMG5 SMG5 nonsense mediated mRNA decay factor
SNAI2 snail family zinc finger 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
TBR1 T-box, brain, 1
TCTN1 tectonic family member 1
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UFSP2 UFM1-specific peptidase 2
XPO1 exportin 1
XPO5 exportin 5
ZC3H11B zinc finger CCCH-type containing 11B pseudogene
ZC3H4 zinc finger CCCH-type containing 4
ZNF414 zinc finger protein 414
ZNF503 zinc finger protein 503