microenvironment Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

414 genes co-occuring with the biological term microenvironment in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ACSL5 acyl-CoA synthetase long-chain family member 5
ACSS2 acyl-CoA synthetase short-chain family member 2
ADA adenosine deaminase
ADAM17 ADAM metallopeptidase domain 17
ADAM8 ADAM metallopeptidase domain 8
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADM adrenomedullin
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
AGER advanced glycosylation end product-specific receptor
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
AICDA activation-induced cytidine deaminase
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALPL alkaline phosphatase, liver/bone/kidney
ALPP alkaline phosphatase, placental
AMH anti-Mullerian hormone
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANGPTL2 angiopoietin-like 2
ANXA2 annexin A2
APOA1 apolipoprotein A-I
APP amyloid beta (A4) precursor protein
AQP4 aquaporin 4
AR androgen receptor
ARF6 ADP-ribosylation factor 6
ARG1 arginase 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARRB1 arrestin, beta 1
ASPN asporin
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
BCL2 B-cell CLL/lymphoma 2
BCR breakpoint cluster region
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BRCA1 breast cancer 1, early onset
BSG basigin (Ok blood group)
BTLA B and T lymphocyte associated
C5 complement component 5
CAMP cathelicidin antimicrobial peptide
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CBX3 chromobox homolog 3
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD24 CD24 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD80 CD80 molecule
CD81 CD81 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHGA chromogranin A
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COL7A1 collagen, type VII, alpha 1
CRBN cereblon
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRYAB crystallin, alpha B
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSPG4 chondroitin sulfate proteoglycan 4
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CTSB cathepsin B
CTSD cathepsin D
CTSK cathepsin K
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DACH1 dachshund family transcription factor 1
DCD dermcidin
DCN decorin
DEFB4A defensin, beta 4A
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DLK1 delta-like 1 homolog (Drosophila)
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DUT deoxyuridine triphosphatase
EBAG9 estrogen receptor binding site associated, antigen, 9
EDN1 endothelin 1
EDNRB endothelin receptor type B
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNA1 ephrin-A1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EMP2 epithelial membrane protein 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPAS1 endothelial PAS domain protein 1
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV5 ets variant 5
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAP fibroblast activation protein, alpha
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
FOXP3 forkhead box P3
FZD4 frizzled class receptor 4
FZD7 frizzled class receptor 7
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GC group-specific component (vitamin D binding protein)
GCSAM germinal center-associated, signaling and motility
GHRL ghrelin/obestatin prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR182 G protein-coupled receptor 182
GREM1 gremlin 1, DAN family BMP antagonist
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRM3 glutamate receptor, metabotropic 3
GSTP1 glutathione S-transferase pi 1
HAS2 hyaluronan synthase 2
HAVCR2 hepatitis A virus cellular receptor 2
HDAC6 histone deacetylase 6
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGFAC HGF activator
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HOXA9 homeobox A9
HOXB9 homeobox B9
HPN hepsin
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPG2 heparan sulfate proteoglycan 2
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
ICAM5 intercellular adhesion molecule 5, telencephalin
ICOSLG inducible T-cell co-stimulator ligand
IDO1 indoleamine 2,3-dioxygenase 1
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGFBP7 insulin-like growth factor binding protein 7
IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker)
IL10 interleukin 10
IL11 interleukin 11
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL21 interleukin 21
IL22 interleukin 22
IL27 interleukin 27
IL3 interleukin 3
IL32 interleukin 32
IL33 interleukin 33
IL4 interleukin 4
IL6 interleukin 6
IL7 interleukin 7
IL7R interleukin 7 receptor
IQGAP1 IQ motif containing GTPase activating protein 1
IRF4 interferon regulatory factor 4
IRF8 interferon regulatory factor 8
ISG15 ISG15 ubiquitin-like modifier
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAG1 jagged 1
JUN jun proto-oncogene
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KITLG KIT ligand
KLF10 Kruppel-like factor 10
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
L1CAM L1 cell adhesion molecule
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LHCGR luteinizing hormone/choriogonadotropin receptor
LMO2 LIM domain only 2 (rhombotin-like 1)
LOX lysyl oxidase
LRP1 low density lipoprotein receptor-related protein 1
LRRC26 leucine rich repeat containing 26
LTA lymphotoxin alpha
MAML1 mastermind-like 1 (Drosophila)
MAPK14 mitogen-activated protein kinase 14
MCAM melanoma cell adhesion molecule
MFGE8 milk fat globule-EGF factor 8 protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR126 microRNA 126
MIR140 microRNA 140
MIR17HG miR-17-92 cluster host gene
MIR195 microRNA 195
MIR20A microRNA 20a
MIR21 microRNA 21
MIR328 microRNA 328
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MST1 macrophage stimulating 1
MTDH metadherin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NDRG1 N-myc downstream regulated 1
NF1 neurofibromin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGFR nerve growth factor receptor
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NOV nephroblastoma overexpressed
OCIAD2 OCIA domain containing 2
OLFM1 olfactomedin 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PADI2 peptidyl arginine deiminase, type II
PALLD palladin, cytoskeletal associated protein
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAX7 paired box 7
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDCD1 programmed cell death 1
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM2 PDZ and LIM domain 2 (mystique)
PEA15 phosphoprotein enriched in astrocytes 15
PGF placental growth factor
PGK1 phosphoglycerate kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
POSTN periostin, osteoblast specific factor
POU5F1 POU class 5 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRF1 perforin 1 (pore forming protein)
PRKD1 protein kinase D1
PRL prolactin
PRMT5 protein arginine methyltransferase 5
PROKR1 prokineticin receptor 1
PROKR2 prokineticin receptor 2
PROM1 prominin 1
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PTAFR platelet-activating factor receptor
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
PTK2 protein tyrosine kinase 2
PTN pleiotrophin
PTPRC protein tyrosine phosphatase, receptor type, C
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAP1B RAP1B, member of RAS oncogene family
RBM3 RNA binding motif (RNP1, RRM) protein 3
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHBDD2 rhomboid domain containing 2
RHOA ras homolog family member A
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
S100A4 S100 calcium binding protein A4
S1PR1 sphingosine-1-phosphate receptor 1
SAA1 serum amyloid A1
SDC4 syndecan 4
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SELPLG selectin P ligand
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SHH sonic hedgehog
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLIT3 slit homolog 3 (Drosophila)
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOST sclerostin
SOX17 SRY (sex determining region Y)-box 17
SOX2 SRY (sex determining region Y)-box 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPP1 secreted phosphoprotein 1
SPRR3 small proline-rich protein 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRY sex determining region Y
SS18 synovial sarcoma translocation, chromosome 18
SSX1 synovial sarcoma, X breakpoint 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STK11 serine/threonine kinase 11
SULF1 sulfatase 1
SULF2 sulfatase 2
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYP synaptophysin
TAC1 tachykinin, precursor 1
TBXA2R thromboxane A2 receptor
TCL1A T-cell leukemia/lymphoma 1A
TEK TEK tyrosine kinase, endothelial
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TMPRSS4 transmembrane protease, serine 4
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNRC6A trinucleotide repeat containing 6A
TP53 tumor protein p53
TPSAB1 tryptase alpha/beta 1
TREM1 triggering receptor expressed on myeloid cells 1
TRIM28 tripartite motif containing 28
TRIM62 tripartite motif containing 62
TSPY1 testis specific protein, Y-linked 1
TWIST1 twist family bHLH transcription factor 1
TWIST2 twist family bHLH transcription factor 2
UCA1 urothelial cancer associated 1 (non-protein coding)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
ULBP2 UL16 binding protein 2
VASP vasodilator-stimulated phosphoprotein
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VTCN1 V-set domain containing T cell activation inhibitor 1
WEE1 WEE1 G2 checkpoint kinase
WNT16 wingless-type MMTV integration site family, member 16
WNT5A wingless-type MMTV integration site family, member 5A
WWTR1 WW domain containing transcription regulator 1
XPA xeroderma pigmentosum, complementation group A
YAP1 Yes-associated protein 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB16 zinc finger and BTB domain containing 16
ZBTB33 zinc finger and BTB domain containing 33
ZEB2 zinc finger E-box binding homeobox 2
ZNF274 zinc finger protein 274